Quality Control of Chinese Medicines
Author: Shaoping Li
Publisher: Springer Nature
Published:
Total Pages: 879
ISBN-13: 9819998719
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Pharmacological Activity-based Quality Control of Chinese Herbs
Author:
Publisher:
Published: 2008
Total Pages: 0
ISBN-13: 9781604568233
DOWNLOAD EBOOK →Natural products are the most successful source of drugs. Of the 877 small-molecule new chemical entities introduced between 1981 and 2002, roughly half were natural products, semi-synthetic natural product analogues or natural mimics. Chinese herbs (traditional Chinese medicines, TCMs) have been used for prevention and treatment of diseases for thousands years. It has been attracting intensive attention in the trends of back to nature. As herbal medicines, the conditions of growth, harvest time, process and storage etc. will undoubtedly affect the presence and concentration of the bioactive constituents, thus affecting their quality and efficacy. Up to date, there are few books focussing on the relationship, which is the bridge between TCM and modern medical science, of traditional clinic uses, pharmacological activities and quality control of Chinese herbs. Unfortunately, bioactive compounds in Chinese herbs are usually not or only partially known. Actually, the active compounds considered in Chinese herbs may be different according to their clinical indication. In addition, it is considered that the curative effect of Chinese herbs is an integrative result of a number of bioactive compounds. Therefore, how to control the quality is a big problem. We would like to discuss the quality control based on their traditional clinical uses and pharmacological activities in this book, which is the fundamental step towards developing and modernising such products into evidence based medicines. It will also help the peoples to understand TCMs in modern scientific angles. This book is designed primarily as a textbook for or adjunct to course in herbal remedies, food safety or quality control of herbs. It is also a professional reference whom is in the area of drug discovery, pharmaceutical analysis and food chemistry.
Current Review of Chinese Medicine
Author: Ping-Chung Leung
Publisher: World Scientific
Published: 2006
Total Pages: 310
ISBN-13: 9812567070
DOWNLOAD EBOOK →Annotation The second volume of this book series on the modern practice of Chinese medicine continues with the focus on evidence-based TCM research. It is even more focused than the preceding one ? providing detailed information about the best sources of herbal supply required for research and drug development purposes. Herbal supply has always been a major concern for TCM researchers because it is difficult to ensure that the supply is of the best quality. Another highlight of the book are the special reviews on the state of Good Agricultural Practice
Current Review Of Chinese Medicine: Quality Control Of Herbs And Herbal Material
Author: Ping-chung Leung
Publisher: World Scientific
Published: 2006-05-02
Total Pages: 310
ISBN-13: 9814478377
DOWNLOAD EBOOK →The second volume of this book series on the modern practice of Chinese medicine continues with the focus on evidence-based TCM research. It is focused on detailed information about the best sources of herbal supply and its quality control required for research and drug development purposes. Herbal quality has always been a major concern for TCM researchers because it is difficult to know which is of the best quality. Some other popular topics are also entertained.
Chinese Materia Medica
Author: You-Ping Zhu
Publisher: CRC Press
Published: 1998-05-28
Total Pages: 718
ISBN-13: 9789057022852
DOWNLOAD EBOOK →Chinese Materia Medica - Chemistry, Pharmacology and Applications provides comprehensive and up-to-date information on the chemistry and pharmacology of commonly-used Chinese herbs. It gives an in-depth profile of the traditional experience of Chinese materia medica with modern scientific explanations. It also features the theories and concepts of Chinese materia medica from the Western medical perspectives, and the sources, production and quality control of Chinese materia medica. This book can be used both as a reference book and a textbook for specialized university and on-the-job training courses. It is essential reading for all students and practitioners of traditional Chinese medicine. It should also be of interest to those in education and research in natural products, pharmaceutical sciences and medicine.
Monographs for Quality Evaluation of Chinese Crude Drugs
Author: Zhengtao Wang
Publisher: Scpg Publishing Corporation
Published: 2015-03-10
Total Pages: 0
ISBN-13: 9781938368196
DOWNLOAD EBOOK →Traditional Chinese Medicine (TCM) has been used for medication in China over thousands of years, and now become more and more accepted as a source of alternative and complementary medicine in western country.Today the chemical analysis is the dominant direction of the quality control system of TCM and natural medicines. But it is difficult to measure the quality for TCM herbs by detecting solely the presence / absence of a single or small number of marker components at very low concentration, especially for the herbs derived from mutliorigins and produced from wide localities, as well as those with unknown principle bioactive components.From this standpoint, it is necessary to use multidisciplinary technologies, integrating the morphological authentication and chemical analysis, qualitative detection and quantitative determination, and physic-chemical analysis and bioassay, in order to distinguish the authentic herb from the adulterant, the superior from the inferior, and to improve the standards of TCM herbs.This book includes 60 commonly used TCM herbs, each involving the following items: definition, location, action and indication, description, microscopic identification, TLC identification, HPLC/GC fingerprint identification (optional), assay, discussion and references.It is a valuable reference of quality evaluation for TCM herbs.Published by SCPG Publishing Corporation and distributed by World Scientific for all markets except China
Liquid Chromatography
Author: Y. Shen
Publisher: Elsevier Inc. Chapters
Published: 2013-01-08
Total Pages: 688
ISBN-13: 0128071249
DOWNLOAD EBOOK →A characteristic of traditional medicinal practices, such as traditional Chinese medicines (TCMs) and Indian ayurveda, is the abundant use of plants as drugs. However, the bottleneck in the use of herbal drugs is the control of their safety, effectiveness, and quality. Good quality control (QC) is necessary to achieve the standards of modern medicines. Liquid chromatography, being a powerful universal separation technique, is widely available in laboratories and easily hyphenated with other spectroscopic and biochemical techniques. A number of LC-based strategies—such as multicomponent quantitation, fingerprinting, bioaffinity chromatography, and on-flow assays for screening—have been used for the comprehensive QC of TCMs, lead finding, and identification of active constituents. In this chapter, the applications and development of such LC-based methods for TCMs and other herbal drugs are presented and discussed. Some future trends are given.
High Performance Liquid Chromatography Fingerprinting Technology of the Commonly-used Traditional Chinese Medicine Herbs
Author: Baochang Cai
Publisher: World Scientific
Published: 2012
Total Pages: 385
ISBN-13: 9814291099
DOWNLOAD EBOOK →This book provides a comprehensive and up-to-date account of the HPLC technology and fingerprints of commonly-used Chinese herbs. It contains HPLC fingerprints of over 40 traditional Chinese medicinal herbs and details of their sources, production and quality control. The book provides a practical review of the techniques, relevant materials, and the particular demands for using HPLC in traditional Chinese medicinal herb applications. It also covers HPLC methods used to analyze the herbs.High-performance liquid chromatography (HPLC) is increasingly used in the field of traditional Chinese medicine for obtaining fingerprints of Chinese medicinal herbs. Advantages such as high speed, high resolution, high sensitivity, stability, accuracy, and automation make it one of the leading techniques used for quality control, standardization of planting, and new drug development in traditional Chinese medicine.To date, no other books on HPLC fingerprints of traditional Chinese medicinal herbs have been published in English. This is the first book in English devoted to providing readers with state-of-the-art information on HPLC applied in the analysis of traditional Chinese medicinal herbs.
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Author: H.Gerhard Vogel
Publisher: Springer Science & Business Media
Published: 2010-12-15
Total Pages: 576
ISBN-13: 3540898905
DOWNLOAD EBOOK →Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Chinese Medicine - Modern Practice
Author: Ping-chung Leung
Publisher: World Scientific
Published: 2005-02-18
Total Pages: 253
ISBN-13: 9814481955
DOWNLOAD EBOOK →Annals of Traditional Chinese Medicine is a new book series dedicated to the promotion of evidence-based TCM research. It features quality reports focusing on curriculum design, research methodology, original investigations of the quality, efficacy and safety of TCM, and evidence-based trials for the management of various clinical conditions.The inaugural volume of this series, Chinese Medicine — Modern Practice, contains chapters on Chinese Herbal Medicine (for AIDS, cancer, cardiovascular disease, cerebral haemorrhage and Alzheimer disease), Acupuncture (for drug withdrawal, anaesthesia and analgesia), Research Methodology and Chinese Medicine Education.The book will be of interest to clinicians in western medicine, mainstream medical researchers, other healthcare professionals, Chinese medicine educators, clinical and basic Chinese medicine researchers, and health science students, particularly Chinese medicine students. It will also be an important resource for TCM regulators to obtain reliable and critical information concerning the evaluation of quality, efficacy and safety of clinical modalities of Chinese medicine.
