Author: Chris H. De Bruyn
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 533
ISBN-13: 1468445537
DOWNLOAD EBOOK →These two volumes, entitled "Purine Metabolism in Man IV" con tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimidine Metabolism," held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting much new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Author: Chris H. De Bruyn
Publisher: Springer
Published: 2012-12-22
Total Pages: 555
ISBN-13: 9781468445558
DOWNLOAD EBOOK →These two volumes, entitled "Purine Metabolism in Man IV" con tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimidine Metabolism," held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting much new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Author: Chris H De Bruyn
Publisher: Springer
Published: 2014-01-15
Total Pages: 578
ISBN-13: 9781468445541
DOWNLOAD EBOOK →Author: Chris H. De Bruyn
Publisher: Springer
Published: 1984-01-01
Total Pages: 0
ISBN-13: 9780306413636
DOWNLOAD EBOOK →These two volumes, entitled "Purine Metabolism in Man IV" con tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimidine Metabolism," held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting much new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Author: A. Rapado
Publisher: Springer
Published: 2012-11-25
Total Pages: 444
ISBN-13: 9781461591429
DOWNLOAD EBOOK →These volumes contain the papers which were presented at the Third International Symposium on Purine Metabolism in Man held in Madrid (Spain) in June, 1979. The previous meetings in the series were held in Tel Aviv (Israel) and in Baden (Austria) in 1973 and 1976, respective1y. The proceedings were also published by Plenum. Knowledge of the pathophysio1ogy of the purines has developed greatly since the 1950's when it was main1y re1ated to c1inica1 gout, and it is now relevant to many fie1ds of Medicine and Biology. These volumes include papers reporting new work on clinical gout and uro1ithiasis as we11 as on some of the subjects which have featured prominently in the previous volumes, including: regulatory aspects of the intermediary metabolism of purines and re1ated com pounds, enzymology, methodology, and the resu1ts of mutations which affect purine metabolism. However, there have been many new develop ments during the last three years and the scope of the communications reflects not only increasing depth of know1edge, but also a widening of the field. This publication has clinical and fundamental imp1i cations for internal medicine, pediatrics, uro1ogy, biochemistry, immunology, genetics, and oncology.
Author: Chris H. M. M. de Bruyn
Publisher: Plenum Publishing Corporation
Published: 1984
Total Pages: 555
ISBN-13: 9780306413636
DOWNLOAD EBOOK →Author: A Rapado
Publisher: Springer
Published: 2014-01-15
Total Pages: 468
ISBN-13: 9781461591412
DOWNLOAD EBOOK →