Author: Hang Fai (Henry) Kwok
Publisher: MDPI
Published: 2019-10-01
Total Pages: 178
ISBN-13: 3039211897
DOWNLOAD EBOOK →Targeted therapy has developed significantly in the last one and half decades, prescribing specific medications for treatment of particular diseases, such as cancer, diabetes, and heart disease. One of the most exciting recent developments in targeted therapies was the isolation of disease-specific molecules from natural resources, such as animal venoms and plant metabolites/toxins, for use as templates for new drug motif designs. In addition, the study of venom proteins/peptides and toxins naturally targeted mammalian receptors and demonstrated high specificity and selectivity towards defined ion channels of cell membranes. Research has also focsed intensely on receptors. The focus of this Special Issue of Toxins addressed the most recent advances using animal venoms, such as frog secretions, bee/ant venoms and plant/fungi toxins, as medicinal therapy. Recent advances in venom/toxin/immunotoxins for targeted cancer therapy and immunotherapy, along with using novel disease-specific venom-based protein/peptide/toxin and currently available FDA-approved drugs for combinationtreatments will be discussed. Finally, we included an overview of select promising toad/snake venom-based peptides/toxins potentially able to address the forthcoming challenges in this field. Both research and review articles proposing novelties or overviews, respectively, were published in this Special Issue after rigorous evaluation and revision by expert peer reviewers.
Author:
Publisher: ScholarlyEditions
Published: 2013-06-21
Total Pages: 71
ISBN-13: 1481681141
DOWNLOAD EBOOK →Venoms—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Snake Venoms in a concise format. The editors have built Venoms—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Snake Venoms in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Venoms—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Dianne Watters
Publisher: Taylor & Francis
Published: 1992
Total Pages: 228
ISBN-13: 9783718651948
DOWNLOAD EBOOK →First published in 1992
Author: Donald M. Miller
Publisher: CRC Press
Published: 1990-10-24
Total Pages: 192
ISBN-13: 9780849360732
DOWNLOAD EBOOK →Ciguatera poisoning is a worldwide problem whose impact has serious health and economic ramifications. Ciguatera Seafood Toxins provides an introduction and technical reference for this syndrome, covering topics such as medical approaches to treatment, legal avenues for those who become poisoned, and an overview of the areas where ciguatera is common. Other chapters in the text discuss research issues, such as assay systems for ciguatera, neurological effects of the disease, and light and electron microscopy studies of tissue exposed to ciguatera-type toxins. The book provides comprehensive coverage of the laboratory techniques used in the purification and molecular characterization of the toxins implicated in the disease, as well as a discussion of the genetic variability of one of the causative organisms (Gambierdiscus toxicus) in culture. This is a "must have" book for anyone concerned with ciguatera poisoning and its legal, scientific, and medical consequences.
Author: Steven I. Baskin
Publisher: CRC Press
Published: 1991-09-23
Total Pages: 714
ISBN-13: 9781439805367
DOWNLOAD EBOOK →What chemicals are poisonous to the heart and why are they toxic? Find out by reading Principles of Cardiac Toxicology. Certain chemicals can produce toxicity by interacting with elements of the cardiovascular system. This book presents the anatomical, physiological, biochemical, and pathological basis for this interaction and describes the
Author: Milton Fingerman
Publisher: CRC Press
Published: 2002-01-01
Total Pages: 272
ISBN-13: 1482279835
DOWNLOAD EBOOK →The marine environment has been, and continues to be, a fruitful source of novel chemical compounds that are not found in terrestrial and freshwater organisms. Many of these substances show potential biomedical applications, which could lead to development of new pharmaceutical products. Research on the utilization of natural products from marine organisms is growing by leaps and bounds; one important reason why being that, investigators, through new diving technologies, are becoming able to explore at greater depths. Studies of these marine natural products include investigations of neuronal membrane-active toxins, ion channel blockers, antitumor and antiviral agents, and anti-inflammatory molecules. This volume is the sixth in the ongoing series.