Author:
Publisher:
Published: 1966
Total Pages: 322
ISBN-13:
DOWNLOAD EBOOK →This report is a complete compilation of the papers presented and the Proceedings of the 2nd Annual Conference on Atmospheric Contamination in Confined Spaces, sponsored by the Aerospace Medical Research Laboratories and held in Dayton, Ohio on 4 and 5 May 1966. Major technical areas discussed by the invited speakers, members of the Open Forum, and Conference attendees included toxicology of space cabin materials, comparative toxicology and pathology of oxygen, and the effects of oxygen on contaminant toxicity.
Author: Elliott S. Harris
Publisher:
Published: 1966
Total Pages: 322
ISBN-13:
DOWNLOAD EBOOK →This report is a complete compilation of the papers presented and the Proceedings of the 2nd Annual Conference on Atmospheric Contamination in Confined Spaces, sponsored by the Aerospace Medical Research Laboratories and held in Dayton, Ohio on 4 and 5 May 1966. Major technical areas discussed by the invited speakers, members of the Open Forum, and Conference attendees included toxicology of space cabin materials, comparative toxicology and pathology of oxygen, and the effects of oxygen on contaminant toxicity.
Author:
Publisher:
Published: 1967
Total Pages: 468
ISBN-13:
DOWNLOAD EBOOK →The report is a complete compilation of the papers presented and the Proceedings of the 3rd Annual Conference on Atmospheric Contamination in Confined Spaces, sponsored by the Aerospace Medical Research Laboratories and held in Dayton, Ohio on 9, 10, and 11 May 1967. Major technical areas discussed by the invited speakers, members of the Open Forum and Conference attendees included toxicological evaluation of atmospheres and contaminants, histopathological evidences of toxicity, evaluation of cabin materials, instruments and detection techniques, measurement of behavioral responses, and life support systems. Included as an Appendix, but not presented at the Conference, is a status report on oxygen toxicity prepared by Dr. Harold Kaplan.
Author: J. D. MacEwen
Publisher:
Published: 1968
Total Pages: 36
ISBN-13:
DOWNLOAD EBOOK →As extensions of previous short-term experiments on the toxicity of oxygen at reduced pressure in animals, long-term continuous exposures of beagle dogs, rhesus monkeys and albino rats and mice were undertaken. The exposures were for 230 days to 100% oxygen at 5 psia. No mortality occurred in the exposed dogs or monkeys. More rats and mice died in the control groups than in the experimental groups, indicating no effects on mortality due to the experimental conditions. The growth rates of control and experimental rats were almost identical, further indicating lack of deleterious effects. Histopathologic examination of tissues was conducted on all four animal species. No differences were observed between exposed animals and their controls in monkeys, rats or mice. Minimal differences consisting of mild bronchitis and mild congestion were seen in the dogs exposed to 100% oxygen at reduced pressure. One exposed dog exhibited severe pulmonary changes associated with acute interstitial bronchial pneumonia. Periodic measurements of blood constituents showed no significant differences attributable to prolonged oxygen exposure at reduced pressure.