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Probabilistic Modeling in Bioinformatics and Medical Informatics

Author: Dirk Husmeier

Publisher: Springer Science & Business Media

Published: 2006-05-06

Total Pages: 511

ISBN-13: 1846281199

Probabilistic Modelling in Bioinformatics and Medical Informatics has been written for researchers and students in statistics, machine learning, and the biological sciences. The first part of this book provides a self-contained introduction to the methodology of Bayesian networks. The following parts demonstrate how these methods are applied in bioinformatics and medical informatics. All three fields - the methodology of probabilistic modeling, bioinformatics, and medical informatics - are evolving very quickly. The text should therefore be seen as an introduction, offering both elementary tutorials as well as more advanced applications and case studies.

Biological Sequence Analysis

Author: Richard Durbin

Publisher: Cambridge University Press

Published: 1998-04-23

Total Pages: 372

ISBN-13: 113945739X

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Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.

Handbook of Statistical Bioinformatics

Author: Henry Horng-Shing Lu

Publisher: Springer Nature

Published: 2022-12-08

Total Pages: 406

ISBN-13: 3662659026

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Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.

Machine Learning, Big Data, and IoT for Medical Informatics

Author: Pardeep Kumar

Publisher: Academic Press

Published: 2021-06-13

Total Pages: 458

ISBN-13: 0128217812

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Machine Learning, Big Data, and IoT for Medical Informatics focuses on the latest techniques adopted in the field of medical informatics. In medical informatics, machine learning, big data, and IOT-based techniques play a significant role in disease diagnosis and its prediction. In the medical field, the structure of data is equally important for accurate predictive analytics due to heterogeneity of data such as ECG data, X-ray data, and image data. Thus, this book focuses on the usability of machine learning, big data, and IOT-based techniques in handling structured and unstructured data. It also emphasizes on the privacy preservation techniques of medical data. This volume can be used as a reference book for scientists, researchers, practitioners, and academicians working in the field of intelligent medical informatics. In addition, it can also be used as a reference book for both undergraduate and graduate courses such as medical informatics, machine learning, big data, and IoT. Explains the uses of CNN, Deep Learning and extreme machine learning concepts for the design and development of predictive diagnostic systems. Includes several privacy preservation techniques for medical data. Presents the integration of Internet of Things with predictive diagnostic systems for disease diagnosis. Offers case studies and applications relating to machine learning, big data, and health care analysis.

Artificial Intelligence in Medicine

Author: David Riaño

Publisher: Springer

Published: 2019-06-19

Total Pages: 431

ISBN-13: 303021642X

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This book constitutes the refereed proceedings of the 17th Conference on Artificial Intelligence in Medicine, AIME 2019, held in Poznan, Poland, in June 2019. The 22 revised full and 31 short papers presented were carefully reviewed and selected from 134 submissions. The papers are organized in the following topical sections: deep learning; simulation; knowledge representation; probabilistic models; behavior monitoring; clustering, natural language processing, and decision support; feature selection; image processing; general machine learning; and unsupervised learning.

Handbook of Statistical Systems Biology

Author: Michael Stumpf

Publisher: John Wiley & Sons

Published: 2011-09-09

Total Pages: 624

ISBN-13: 1119952042

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Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book: Provides a comprehensive account of inference techniques in systems biology. Introduces classical and Bayesian statistical methods for complex systems. Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems. Discusses various applications for statistical systems biology, such as gene regulation and signal transduction. Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies. Presents an in-depth presentation of reverse engineering approaches. Provides colour illustrations to explain key concepts. This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.

Supply Chain Management: Concepts, Methodologies, Tools, and Applications

Author: Management Association, Information Resources

Publisher: IGI Global

Published: 2012-12-31

Total Pages: 1880

ISBN-13: 1466626755

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In order to keep up with the constant changes in technology, business have adopted supply chain management to improve competitive strategies on a strategic and operational level. Supply Chain Management: Concepts, Methodologies, Tools, and Applications is a reference collection which highlights the major concepts and issues in the application and advancement of supply chain management. Including research from leading scholars, this resource will be useful for academics, students, and practitioners interested in the continuous study of supply chain management and its influences.

Hybrid Artificial Intelligent Systems

Author: Francisco Javier de Cos Juez

Publisher: Springer

Published: 2018-06-09

Total Pages: 765

ISBN-13: 331992639X

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This volume constitutes the refereed proceedings of the 13th International Conference on Hybrid Artificial Intelligent Systems, HAIS 2018, held in Oviedo, Spain, in June 2018. The 62 full papers published in this volume were carefully reviewed and selected from 104 submissions. They are organized in the following topical sections: Neurocomputing, fuzzy systems, rough sets, evolutionary algorithms, Agents andMultiagent Systems, and alike.

Pattern Recognition in Computational Molecular Biology

Author: Mourad Elloumi

Publisher: John Wiley & Sons

Published: 2015-12-24

Total Pages: 656

ISBN-13: 1119078865

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A comprehensive overview of high-performance pattern recognition techniques and approaches to Computational Molecular Biology This book surveys the developments of techniques and approaches on pattern recognition related to Computational Molecular Biology. Providing a broad coverage of the field, the authors cover fundamental and technical information on these techniques and approaches, as well as discussing their related problems. The text consists of twenty nine chapters, organized into seven parts: Pattern Recognition in Sequences, Pattern Recognition in Secondary Structures, Pattern Recognition in Tertiary Structures, Pattern Recognition in Quaternary Structures, Pattern Recognition in Microarrays, Pattern Recognition in Phylogenetic Trees, and Pattern Recognition in Biological Networks. Surveys the development of techniques and approaches on pattern recognition in biomolecular data Discusses pattern recognition in primary, secondary, tertiary and quaternary structures, as well as microarrays, phylogenetic trees and biological networks Includes case studies and examples to further illustrate the concepts discussed in the book Pattern Recognition in Computational Molecular Biology: Techniques and Approaches is a reference for practitioners and professional researches in Computer Science, Life Science, and Mathematics. This book also serves as a supplementary reading for graduate students and young researches interested in Computational Molecular Biology.

Hidden Markov Models for Bioinformatics

Author: T. Koski

Publisher: Springer Science & Business Media

Published: 2001-11-30

Total Pages: 422

ISBN-13: 9781402001352

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The purpose of this book is to give a thorough and systematic introduction to probabilistic modeling in bioinformatics. The book contains a mathematically strict and extensive presentation of the kind of probabilistic models that have turned out to be useful in genome analysis. Questions of parametric inference, selection between model families, and various architectures are treated. Several examples are given of known architectures (e.g., profile HMM) used in genome analysis.