Principles of Neural Science

Principles of Neural Science PDF

Author: Eric R. Kandel

Publisher:

Published: 2021

Total Pages: 1646

ISBN-13: 9781264267682

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The goal of this sixth edition of Principles of Neural Science is to provide readers with insight into how genes, molecules, neurons, and the circuits they form give rise to behavior. With the exponential growth in neuroscience research over the 40 years since the first edition of this book, an increasing challenge is to provide a comprehensive overview of the field while remaining true to the original goal of the first edition, which is to elevate imparting basic principles over detailed encyclopedic knowledge.

Principles of Neurobiology

Principles of Neurobiology PDF

Author: Liqun Luo

Publisher: Garland Science

Published: 2020-09-05

Total Pages: 761

ISBN-13: 1000096807

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Principles of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors.

Principles of Neural Science, Sixth Edition

Principles of Neural Science, Sixth Edition PDF

Author: Eric R. Kandel

Publisher: McGraw Hill Professional

Published: 2021-04-05

Total Pages: 1698

ISBN-13: 1259642240

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The gold standard of neuroscience texts―updated with hundreds of brand-new images and fully revised content in every chapter Doody's Core Titles for 2023! For more than 40 years, Principles of Neural Science has helped readers understand the link between the human brain and behavior. As the renowned text has shown, all behavior is an expression of neural activity and the future of both clinical neurology and psychiatry is dependent on the progress of neural science. Fully updated, this sixth edition of the landmark reference reflects the latest research, clinical perspectives, and advances in the field. It offers an unparalleled perspective on the the current state and future of neural science. This new edition features: Unmatched coverage of how the nerves, brain, and mind function NEW chapters on: - The Computational Bases of Neural Circuits that Mediate Behavior - Brain-Machine Interfaces - Decision-Making and Consciousness NEW section on the neuroscientific principles underlying the disorders of the nervous system Expanded coverage of the different forms of human memory Highly detailed chapters on stroke, Parkinson’s disease, and multiple sclerosis 2,200 images, including 300 new color illustrations, diagrams, radiology studies, and PET scans Principles of Neural Science, Sixth Edition benefits from a cohesive organization, beginning with an insightful overview of the interrelationships between the brain, nervous system, genes, and behavior. The text is divided into nine sections: Part I: Overall Perspective provides an overview of the broad themes of neural science, including the basic anatomical organization of the nervous system and the genetic bases of nervous system function and behavior. Part II: Cell and Molecular Biology of Cells of the Nervous System examines the basic properties of nerve cells, including the generation and conduction of propagated signaling. Part III: Synaptic Transmission focuses on the electrophysiological and molecular mechanism of synaptic transmission with chapters on neuronal excitability, neurotransmitters, and transmitter release. Part IV: Perception discusses the various aspects of sensory perception, including how information from the primary organs of sensation is transmitted to and processed by the central nervous system. Part V: Movement considers the neural mechanisms underlying movement and examines a new treatment that addresses how the basal ganglia regulate the selection of motor actions and instantiate reinforcement learning. Part VI: The Biology of Emotion, Motivation and Homeostasis examines the neural mechanisms by which subcortical areas mediate homeostatic control mechanisms, emotions, and motivation. Part VII: Development and the Emergence of Behavior looks at the nervous system from early embryonic differentiation to the formation and elimination of synapses. Part VIII: Learning, Memory, Language and Cognition expands on the previous section, examining the cellular mechanisms of implicit and explicit memory storage, as well as decision-making and consciousness. Part IX: explores the neural mechanisms underlying diseases and disorders of the nervous system, including autism spectrum disorder, epilepsy, schizophrenia, and anxiety.

Principles of Neural Design

Principles of Neural Design PDF

Author: Peter Sterling

Publisher: MIT Press

Published: 2017-06-09

Total Pages: 567

ISBN-13: 0262534681

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Two distinguished neuroscientists distil general principles from more than a century of scientific study, “reverse engineering” the brain to understand its design. Neuroscience research has exploded, with more than fifty thousand neuroscientists applying increasingly advanced methods. A mountain of new facts and mechanisms has emerged. And yet a principled framework to organize this knowledge has been missing. In this book, Peter Sterling and Simon Laughlin, two leading neuroscientists, strive to fill this gap, outlining a set of organizing principles to explain the whys of neural design that allow the brain to compute so efficiently. Setting out to “reverse engineer” the brain—disassembling it to understand it—Sterling and Laughlin first consider why an animal should need a brain, tracing computational abilities from bacterium to protozoan to worm. They examine bigger brains and the advantages of “anticipatory regulation”; identify constraints on neural design and the need to “nanofy”; and demonstrate the routes to efficiency in an integrated molecular system, phototransduction. They show that the principles of neural design at finer scales and lower levels apply at larger scales and higher levels; describe neural wiring efficiency; and discuss learning as a principle of biological design that includes “save only what is needed.” Sterling and Laughlin avoid speculation about how the brain might work and endeavor to make sense of what is already known. Their distinctive contribution is to gather a coherent set of basic rules and exemplify them across spatial and functional scales.

Guide to Research Techniques in Neuroscience

Guide to Research Techniques in Neuroscience PDF

Author: Matt Carter

Publisher: Academic Press

Published: 2022-03-26

Total Pages: 416

ISBN-13: 0323915612

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Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step

Essentials of Neural Science and Behavior

Essentials of Neural Science and Behavior PDF

Author: Eric R. Kandel

Publisher: McGraw Hill Professional

Published: 1995

Total Pages: 358

ISBN-13: 9780838522455

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This textbook presents the fundamental principles of neuroscience and its effect on behavior. Neuroscience is the scientific study of the nervous system. Topics will include: principles of brain organization; structure and ultrastructure of neurons; neurophysiology and biophysics of excitable cells; synaptic transmission; neurotransmitter systems and neurochemistry; molecular biology of neurons; development and plasticity of the brain; aging and diseases of the nervous system; organization of sensory and motor systems; structure and function of cerebral cortex; modeling of neural systems. It also examines such topics as mammalian sensory, motor, regulatory, and motivational mechanisms involved in the control of behavior, and higher mental processes such as those involved in language and memory.

Neuroradiology Signs

Neuroradiology Signs PDF

Author: Mai-Lan Ho

Publisher: McGraw Hill Professional

Published: 2014-04-22

Total Pages: 493

ISBN-13: 0071804331

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A COMPREHENSIVE, FULL-COLOR GUIDE TO NEURORADIOLOGY SIGNS ACROSS ALL IMAGING MODALITIES The first book of its kind, Neuroradiology Signs provides a multimodality review of more than 440 neuroradiologic signs in CT, MR, angiography, radiography, ultrasound, and nuclear medicine. It is designed to enhance your recognition of specific imaging patterns, enabling you to arrive at an accurate diagnosis. Neuroradiology Signs consists of 7 chapters: Adult and General Brain Pediatric Brain Head, Neck, and Orbits Vascular Skull and Facial Bones Vertebrae Spinal Cord and Nerves All cases have been reviewed by subspecialty experts and include: Imaging Findings Modalities Differential Diagnosis Discussion References Full-color photographs illustrate sign etymology and enhance your learning experience. The index is conveniently organized by sign, diagnosis, and modality. Neuroradiology Signs is a valuable review for trainees preparing for board examinations and a trusted daily reference for practicing clinicians.

Volpe's Neurology of the Newborn E-Book

Volpe's Neurology of the Newborn E-Book PDF

Author: Joseph J. Volpe

Publisher: Elsevier Health Sciences

Published: 2017-09-13

Total Pages: 1526

ISBN-13: 0323508650

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A clear, engaging writing style, hundreds of full-color images, and new information throughout make Volpe’s Neurology of the Newborn, 6th Edition, an indispensable resource for those who provide care for neonates with neurological conditions. World authority Dr. Joseph Volpe, along with Dr. Terrie E. Inder and other distinguished editors, continue the unparalleled clarity and guidance you’ve come to expect from the leading reference in the field – keeping you up to date with today’s latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology. Features a brand new, full-color design with hundreds of new figures, tables, algorithms, and micrographs. Includes two entirely new chapters: Neurodevelopmental Follow-Up and Stroke in the Newborn; a new section on Neonatal Seizures; and an extensively expanded section on Hypoxic-Ischemia and Other Disorders. Showcases the experience and knowledge of a new editorial team, led by Dr. Joseph Volpe and Dr. Terrie E. Inder, Chair of the Department of Pediatric Newborn Medicine at Brigham and Women’s Hospital, all of whom bring a wealth of insight to this classic text. Offers comprehensive updates from cover to cover to reflect all of the latest information regarding the development of the neural tube; prosencephalic development; congenital hydrocephalus; cerebellar hemorrhage; neuromuscular disorders and genetic testing; and much more. Uses an improved organization to enhance navigation.