Precision Psychiatry

Precision Psychiatry PDF

Author: Leanne M. Williams, Ph.D.

Publisher: American Psychiatric Pub

Published: 2021-10-15

Total Pages: 302

ISBN-13: 1615371583

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Precision psychiatry, as outlined in this groundbreaking book, presents a new path forward. By integrating findings from basic and clinical neuroscience, clinical practice, and population-level data, the field seeks to develop therapeutic approaches tailored for specific individuals with a specific constellation of health issues, characteristics, strengths, and symptoms.

Frontiers in Psychiatry

Frontiers in Psychiatry PDF

Author: Yong-Ku Kim

Publisher: Springer Nature

Published: 2019-11-09

Total Pages: 641

ISBN-13: 9813297212

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This book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new discoveries and treatments. Emerging research methods for precision medicine are discussed, as are a variety of novel theoretical frameworks for research, such as theoretical psychiatry, the developmental approach to the definition of psychopathology, and the theory of constructed emotion. The concluding section considers novel interventions and treatment avenues, including psychobiotics, the use of neuromodulation to augment cognitive control of emotion, and the role of the telomere-telomerase system in psychopharmacological interventions.

Personalized Psychiatry

Personalized Psychiatry PDF

Author: Bernhard Baune

Publisher: Academic Press

Published: 2019-10-16

Total Pages: 604

ISBN-13: 0128131772

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Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Precision Medicine for Investigators, Practitioners and Providers

Precision Medicine for Investigators, Practitioners and Providers PDF

Author: Joel Faintuch

Publisher: Academic Press

Published: 2019-11-16

Total Pages: 640

ISBN-13: 0128191791

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Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked

Major Depressive Disorder

Major Depressive Disorder PDF

Author: Yong-Ku Kim

Publisher: Springer Nature

Published: 2021-04-08

Total Pages: 555

ISBN-13: 9813360445

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This book reviews all aspects of major depressive disorder (MDD), casting light on its neurobiological underpinnings and describing the most recent advances in management. The book is divided into four sections, the first of which discusses MDD from a network science perspective, highlighting the alterations in functional and structural connectivity and presenting insights achieved through resting state functional MRI and the development of neuroimaging-based biomarkers. The second section examines important diagnostic and neurobiological issues, while the third considers the currently available specific treatments for MDD, including biofeedback, neurofeedback, cognitive behavioral therapy, acceptance and commitment therapy, neuromodulation therapy, psychodynamic therapy, and complementary and alternative medicine. A concluding section is devoted to promising emerging treatments, from novel psychopharmacological therapies through to virtual reality treatment, immunotherapy, biomarker-guided tailored therapy, and more. Written by leading experts from across the world, the book will be an excellent source of information for both researchers and practitioners.

The American Psychiatric Association Publishing Textbook of Psychiatry

The American Psychiatric Association Publishing Textbook of Psychiatry PDF

Author: Laura Weiss Roberts

Publisher: American Psychiatric Pub

Published: 2019-05-02

Total Pages: 1378

ISBN-13: 1615372563

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The American Psychiatric Association Publishing Textbook of Psychiatry, first published more than 30 years ago, is a landmark text with a legacy of sound scholarship, expert knowledge, and effective pedagogy. Thoroughly revised and featuring new authors and content, the seventh edition raises the bar, adding age-related, cultural, societal, and population considerations in the practice of psychiatry to the authoritative text that generations of students, residents, and clinicians have heretofore relied upon. The book first focuses on foundational knowledge, with chapters on psychiatric interviewing, diagnostic formulation, developmental assessment, laboratory testing and neuroimaging, and ethical and legal aspects of clinical psychiatry, and then proceeds to a full presentation of psychiatric disorders in alignment with DSM-5. The third section offers an overview of treatment strategies and methods in present-day psychiatry, a combination of evidence-based biological interventions and psychotherapies, and gives a clear sense of exciting new directions in psychiatric therapeutics. The final section of the textbook is focused on the care of special patient populations, including women; children and adolescents; lesbian, gay, bisexual, and transgender individuals; older adults; and culturally diverse individuals. Many topics are new to this volume, including the following: Suicide risk assessment, a critically important subject, is addressed in a new chapter that provides the reader with up-to-date knowledge needed to conduct a thorough, attuned, and accurate psychiatric interview in line with best practices. A new chapter on the social determinants of mental health has been added, reflecting an increased emphasis on populations whose specific concerns have been historically underappreciated in American psychiatry, and illuminating factors that influence mental health needs and barriers to care in specific patient populations. Precision psychiatry, an integrative approach that pulls together the scientific foundation of the discipline and recent technological advances and directs them toward closing the gap between discovery and clinical translation, is explored in a new chapter. E-health strategies in mental health have become increasingly available to psychiatrists and other health professionals, especially in the mobile and monitoring spheres. A new chapter offers insights into these intriguing new options for delivering treatment. A chapter on complementary and integrative therapies explores the integration of conventional medicine with alternative treatments for which there is an evidence base, providing an overview of nutrients, phytomedicines, hormones, mind--body practices, and electromagnetic treatments. With features such as key clinical points and recommended readings for further study, The American Psychiatric Association Publishing Textbook of Psychiatry is a comprehensive course book, an indispensable reference, and the ultimate resource for clinical care.

Precision Medicine in Clinical Practice

Precision Medicine in Clinical Practice PDF

Author: Mandana Hasanzad

Publisher: Springer Nature

Published: 2022-09-30

Total Pages: 259

ISBN-13: 9811950822

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The book provides complete information on the cornerstones of precision medicine through the omics approach. Clinical applications of genomics and precision medicine have progressed from a theoretical wish list to an impactful force in medical practice.Step-by-step descriptions are provided from basics to the future application and its benefit in clinical practice. Precision medicine aims to personalize health care by tailoring decisions and treatments to each individual in every possible way. Precision medicine includes pharmacogenomics. Essential information is provided on the role of precision medicine and pharmacogenomics in the clinical practice of cancer, cardiovascular disease, diabetes, psychiatric disease, and also the importance for healthcare professionals. This book will assist the practitioners how to integrate precision medicine and pharmacogenomics data into their clinical practice. It is hoped that physicians, pharmacists, and scientists with basic scientific knowledge of precision medicine will findthis book useful.

Healing

Healing PDF

Author: Thomas Insel, MD

Publisher: Penguin

Published: 2022-02-22

Total Pages: 337

ISBN-13: 0593298047

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A bold, expert, and actionable map for the re-invention of America’s broken mental health care system. “Healing is truly one of the best books ever written about mental illness, and I think I’ve read them all." —Pete Earley, author of Crazy As director of the National Institute of Mental Health, Dr. Thomas Insel was giving a presentation when the father of a boy with schizophrenia yelled from the back of the room, “Our house is on fire and you’re telling me about the chemistry of the paint! What are you doing to put out the fire?” Dr. Insel knew in his heart that the answer was not nearly enough. The gargantuan American mental health industry was not healing millions who were desperately in need. He left his position atop the mental health research world to investigate all that was broken—and what a better path to mental health might look like. In the United States, we have treatments that work, but our system fails at every stage to deliver care well. Even before COVID, mental illness was claiming a life every eleven minutes by suicide. Quality of care varies widely, and much of the field lacks accountability. We focus on drug therapies for symptom reduction rather than on plans for long-term recovery. Care is often unaffordable and unavailable, particularly for those who need it most and are homeless or incarcerated. Where was the justice for the millions of Americans suffering from mental illness? Who was helping their families? But Dr. Insel also found that we do have approaches that work, both in the U.S. and globally. Mental illnesses are medical problems, but he discovers that the cures for the crisis are not just medical, but social. This path to healing, built upon what he calls the three Ps (people, place, and purpose), is more straightforward than we might imagine. Dr. Insel offers a comprehensive plan for our failing system and for families trying to discern the way forward. The fruit of a lifetime of expertise and a global quest for answers, Healing is a hopeful, actionable account and achievable vision for us all in this time of mental health crisis.