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Practical Process Research and Development

Author: Neal G. Anderson

Publisher: Academic Press

Published: 2012-05-23

Total Pages: 489

ISBN-13: 0123865387

Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights:• Reflects the current thinking in chemical process R&D for small molecules• Retains similar structure and orientation to the first edition. • Contains approx. 85% new material• Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up)• Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes)• Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more Presents guidelines for implementing and troubleshooting processes

Practical Process Research and Development

Author: Neal G. Anderson

Publisher: Academic Press

Published: 2012-04-09

Total Pages: 489

ISBN-13: 0123865379

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Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights: . Reflects the current thinking in chemical process R&D for small molecules . Retains similar structure and orientation to the first edition. . Contains approx. 85% new material . Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up) . Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes) . Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more Presents guidelines for implementing and troubleshooting processes

Practical Process Research & Development

Author: Neal G. Anderson

Publisher: Academic Press

Published: 2000-03

Total Pages: 354

ISBN-13: 9781483299778

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This book provides a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries. Process R&D describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R&D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students. * Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" * Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more * Includes over 100 tips for rapid process development * Presents guidelines for implementing and troubleshooting processes

Medical Writing in Drug Development

Author: Robert J Bonk

Publisher: Routledge

Published: 2014-01-02

Total Pages: 193

ISBN-13: 1317971418

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A guide through the maze of the pharmaceutical research and development process, Medical Writing in Drug Development fills a gap in the libraries of technical writers, college instructors, and corporate professionals associated with the pharmaceutical process. As it discusses critical information, such as strategies and techniques pivotal to crafting documents for drug development, it also overviews drug research, document types, the roles of professional writers, and information technology. In no time at all, you will be creating persuasive technical documents, building complex facts into coherent messages, and contributing to the effective marketing of new products with promotional pieces that meet legal and ethical standards. Medical Writing in Drug Development helps medical writers and scientific, regulatory, and marketing professionals develop a working knowledge of the technical documents crucial to successful drug research. New and seasoned professional writers alike will benefit from the book's detailed discussions of: using abstracts, slides, and posters to present up-to-the-minute research how patient-education materials, health-economic assessments, and electronic journals provide ongoing challenges in medical writing a dossier approach that expedites regulatory submissions for international drug development structural constraints and rhetorical approaches toward regulatory documents presenting intricate information in scientifically unbiased, yet technically convincing language the effects of electronic publishing, computer graphics, and related technology on the practice of medical writing within pharmaceutical research Practical as a foundation text for undergraduate, graduate, and certificate programs in pharmaceutical or medical technical writing, Medical Writing in Drug Development will help you develop practical strategies for handling journal manuscripts, conference materials, and promotional pieces. No other text will clarify the main aspects of the pharmaceutical research and development process while offering you insight on the key issues dominating the healthcare arena.

Practical Synthetic Organic Chemistry

Author: Stéphane Caron

Publisher: John Wiley & Sons

Published: 2020-02-05

Total Pages: 850

ISBN-13: 1119448859

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This book is a hands-on guide for the organic chemist. Focusing on the most reliable and useful reactions, the chapter authors provide the information necessary for a chemist to strategically plan a synthesis, as well as repeat the procedures in the laboratory. Consolidates all the key advances/concepts in one book, covering the most important reactions in organic chemistry, including substitutions, additions, eliminations, rearrangements, oxidations, reductions Highlights the most important reactions, addressing basic principles, advantages/disadvantages of the methodology, mechanism, and techniques for achieving laboratory success Features new content on recent advances in CH activation, photoredox and electrochemistry, continuous chemistry, and application of biocatalysis in synthesis Revamps chapters to include new and additional examples of chemistry that have been demonstrated at a practical scale

Collaborative Research and Development Projects

Author: Tom Harris

Publisher: Springer Science & Business Media

Published: 2007-04-18

Total Pages: 175

ISBN-13: 3540460535

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This volume will help individuals and organizations, from both academia and industry, to effectively work together on R&D projects. This inspiring and highly readable book covers winning grant support, the legal arrangements, working with academics and practitioners, managing project progress, and exploiting the project results. Step-by-step coverage guides a project team though a challenging venture, helping them avoid potential pitfalls.

Software Process Improvement and Management: Approaches and Tools for Practical Development

Author: Fauzi, Shukor Sanim Mohd

Publisher: IGI Global

Published: 2011-11-30

Total Pages: 284

ISBN-13: 1613501420

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Over the past decade, there has been an increase in attention and focus on the discipline of software engineering. Software engineering tools and techniques have been developed to gain more predictable quality improvement results. Process standards such as Capability Maturity Model Integration (CMMI), ISO 9000, Software Process Improvement and Capability dEtermination (SPICE), Agile Methodologies, and others have been proposed to assist organizations to achieve more predictable results by incorporating these proven standards and procedures into their software process. Software Process Improvement and Management: Approaches and Tools for Practical Development offers the latest research and case studies on software engineering and development. The production of new process standards assist organizations and software engineers in adding a measure of predictability to the software process. Companies can gain a decisive competitive advantage by applying these new and theoretical methodologies in real-world scenarios. Researchers, scholars, practitioners, students, and anyone interested in the field of software development and design should access this book as a major compendium of the latest research in the field.

Research for Development

Author: Sophie Laws

Publisher: SAGE

Published: 2003-06-25

Total Pages: 500

ISBN-13: 9780761973270

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`[Research for Development] is well-written and, at every stage, is well-documented with practical examples. The simplicity with which it is written adds to its value in that non-professional persons get well-aquainted with the research process. Every chapter in the book ends with highlighting of the main points made in that chapter... A further strength of the book is the inclusion of an appendix with a list of websites that deal with issues in the area of development research... the simplicity of its organization and message should appeal to people/researchers across disciplines' - Pakistan Development Review `Research for Development achieves the near impossible: it provides vast quantities of useful guidance for almost anyone involved in research for development regardless of the size of your research project or your role within that project' - Arvac Bulletin `Written by professional researchers, this immensely practical book provides development workers with a more research-oriented point of view, so that they can avoid mistakes in the design of programmes. It will also help them to understand people's needs and respond accordingly' - The Asian Age `It is a beautiful and comprehensive compilation giving scores of instances that prove the essentiality if carrying out a survey of a particular locality for bringing about a change there' - Rafique Jalal, DAWN This book provides a comprehensive introduction and handbook for undertaking and managing research in development. It is designed to provide both a quick reference manual and an indispensable learning tool for all students, researchers and practitioners engaged in development work. The text is divided into two parts: Managing research for development, and Doing research for development. Together the two parts review the complete research process from outlining the essential role and purpose of research, highlighting specific issues to development research, to demonstrating how to evaluate and secure the best results from subsequent research projects. The book includes: an overview of different types of research in development work; practical steps to writing a brief and managing research; practical steps to evaluating and promoting research findings; step by step guides to getting started and choosing a research method; detailed guidelines to seven key research techniques; examples, exercises, summaries and checklists; and glossary and guides to additional resources and packages Drawing on considerable hands-on experience, Research for Development will be an essential companion and invaluable tool for anyone engaged in contemporary development research, development work and development studies.

Doing Developmental Research

Author: Tricia Striano

Publisher: Guilford Publications

Published: 2016-02-10

Total Pages: 192

ISBN-13: 1462524435

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Addressing practical issues rarely covered in methods texts, this user-friendly, jargon-free book helps students and beginning researchers plan infant and child development studies and get them done. The author provides step-by-step guidance for getting involved in a developmental laboratory and crafting effective research questions and proposals. Tips on recruiting study participants cover access issues--such as how to overcome language and cultural barriers--and include helpful sample scripts. The book offers time management strategies, pointers for organizing and communicating data, and a roadmap of the journal publication process, complete with an annotated sample article. Numerous concrete examples, checklists, worksheets, and exercises are featured. Reproducible forms can be downloaded and printed in a convenient 8 1/2" x 11" size. Pedagogical Features: *Chapter subheadings written as questions to help students quickly find the answers they need. *Boxed key tips and checklists for managing each phase of a study. *Exercises that build core research skills. *Annotated sample journal article with commentary on the writing and publication process.

Applied Research Design

Author: Terry Elizabeth Hedrick

Publisher: SAGE Publications

Published: 1993-01-11

Total Pages: 193

ISBN-13: 1506319440

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"The Terry E. Hedrick, Leonard Bickman, and Debra J. Rog text provides a framework for designing research that is adaptable to almost any applied setting and constantly reiterates the need for establishing and maintaining credibility with the client at each level of the research process. Although the applied research book is a practical guide, suitable to accompany any thorough applied design textbook, it does a comprehensive job of presenting the distinction between basic and applied research. It introduces many topics found in the general methodology textbooks. This overlap will help students to feel comfortable in using the general skills in a more specific and complex manner." --Contemporary Psychology "For researchers needing to know how to plan and design applied research projects, Applied Research Design will be a most welcome publication. . . . The writing is clear and concise, graphics are utilized helpfully, and this book will be much appreciated by beginning social scientists who are serious but uncertain about the methodologies possible for doing applied research." --Academic Library Book Review Aimed at helping researchers and students make the transition from the classroom and the laboratory to the "real" world, the authors reveal pitfalls to avoid and strategies to undertake in order to overcome obstacles in the design and planning of applied research. Applied Research Design focuses on refining research questions when actual events force deviations from the original analysis. To accomplish this, the authors discuss how to study and monitor program implementation, statistical power analysis, and how to assess the human and material resources needed to conduct an applied research design to facilitate the management of data collection, analysis, and interpretation. Appropriate for professionals and researchers who have had some previous exposure to research methods, this book will enable the development of research strategies that are credible, useful, and--more important--feasible.