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Translational Research in Traumatic Brain Injury

Author: Daniel Laskowitz

Publisher: CRC Press

Published: 2016-04-21

Total Pages: 388

ISBN-13: 1498766579

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Post-traumatic Epilepsy

Author: Marco Mula

Publisher: Cambridge University Press

Published: 2021-08-26

Total Pages: 201

ISBN-13: 1108494226

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A comprehensive overview of post-traumatic epilepsy and its management, long-term consequences, and the rehabilitation needs of patients. Covering the neurobiology, epidemiology, and the neuropsychiatric aspects of traumatic brain injuries, special populations such as paediatric patients and athletes with concussive injuries are also discussed.

Jasper's Basic Mechanisms of the Epilepsies

Author: Jeffrey Noebels

Publisher: OUP USA

Published: 2012-06-29

Total Pages: 1258

ISBN-13: 0199746540

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Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Post-traumatic Epilepsy, Part 1

Author: Marco Mula

Publisher: Cambridge University Press

Published: 2021-08-26

Total Pages: 201

ISBN-13: 1108645623

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Epilepsy is one of the most common neurological conditions, affecting up to seventy million people worldwide, with post-traumatic epilepsy (PTE) accounting for up to 20% of symptomatic cases. Despite this, there is a dearth of information about PTE available for clinicians. This book will guide readers through the neurobiology of PTE and the long-term consequences and rehabilitation needs of patients. Emerging topics such as concussive convulsions in sports are examined and a chapter dedicated to PTE in children ensures readers have the latest knowledge for treating this high-risk subpopulation. Managing PTE in medium and low-income countries where access to appropriate treatment, and even diagnostic equipment, is often poor, is covered in depth. This book is an up-to-date, comprehensive overview of PTE by active international authorities in the field of epilepsy and traumatic brain injury, with an emphasis on epidemiology, neurobiology, clinical problems as well as management issues.

Epilepsy After Non-missile Head Injuries

Author: Bryan Jennett

Publisher:

Published: 1975

Total Pages: 200

ISBN-13:

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The Causes of Epilepsy

Author: Simon Shorvon

Publisher: Cambridge University Press

Published: 2019-05-02

Total Pages: 1013

ISBN-13: 1108420753

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Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.

Animal Models of Acute Neurological Injuries

Author: Jun Chen

Publisher: Springer Science & Business Media

Published: 2008-12-16

Total Pages: 490

ISBN-13: 1603271856

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Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.

Posttraumatic Epilepsy

Author: Carrie R. Jonak

Publisher: Elsevier

Published: 2022-10-21

Total Pages: 202

ISBN-13: 0323886345

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Posttraumatic Epilepsy: Basic and Clinical Aspects provides a synthesized resource on the recent basic and clinical science developments in the field of posttraumatic epilepsy. This book provides a clear understanding of the history of studies and epidemiology of posttraumatic epilepsy after head injury. The book also considers the neuropathology of posttraumatic epilepsy and clinical trials of antiepileptogenic agents evaluated after traumatic brain injury. The book covers the basic science of animal models of traumatic brain injury and the necessary and sufficient changes that must occur to generate epilepsy after head trauma. The authors explore potential mechanisms and novel therapeutic approaches to prevent posttraumatic epilepsy. The book is written for basic and clinical researchers in neuroscience as well as for clinicians treating patients with epilepsy. Reviews the history and epidemiology of posttraumatic epilepsy Considers the neuropathology of posttraumatic epilepsy Synthesizes studies demonstrating risk factors for susceptibility to epilepsy after head trauma Reviews animal models of traumatic brain injury Addresses our current understanding of mechanisms of posttraumatic epilepsy Explores novel therapeutic approaches to prevent posttraumatic epilepsy

Models of Seizures and Epilepsy

Author: Asla Pitkänen

Publisher: Academic Press

Published: 2017-06-14

Total Pages: 1180

ISBN-13: 012804067X

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Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Neurology and Trauma

Author: Randolph W. Evans M.D.

Publisher: Oxford University Press

Published: 2006-03-16

Total Pages: 823

ISBN-13: 0199744912

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Disorders due to trauma to the head, spine, and peripheral nerves are among the most common seen by neurologists and neurosurgeons. This 42 chapter book is the comprehensive, definitive work on the subject, offering coverage on a wide range of clinical issues. The second edition features completely new sections on sports and neurologic trauma and iatrogenic trauma to complement existing comprehensive sections on head trauma, spinal trauma, plexus and peripheral nerve injuries, post-traumatic pain syndromes, environmental trauma, and posttraumatic sequelae and medicolegal aspects. Twenty-two of the first edition's chapters have been revised and updated, eight with new coauthors, and 20 new chapters have been added.