Systematics and the Exploration of Life

Systematics and the Exploration of Life PDF

Author: Philippe Grandcolas

Publisher: John Wiley & Sons

Published: 2021-03-31

Total Pages: 242

ISBN-13: 1119489172

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This book's aim is to obtain and organize knowledge about the diversity of living things. Their epistomological and methodological fundamentals are explained in the framework of the biology of evolution. The methods of construction and use of phylogenetic trees are presented as well as the classification and description of taxa with the nomenclature rules.

Holland-Frei Cancer Medicine

Holland-Frei Cancer Medicine PDF

Author: Robert C. Bast, Jr.

Publisher: John Wiley & Sons

Published: 2017-03-10

Total Pages: 2008

ISBN-13: 111900084X

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Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Point Mutation

Point Mutation PDF

Author: Colin Logie

Publisher: BoD – Books on Demand

Published: 2012-03-21

Total Pages: 356

ISBN-13: 9535103318

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This book concerns the signatures left behind in chromosomes by the forces that drive DNA code evolution in the form of DNA nucleotide substitutions. Since the genetic code predetermines the molecular basis of life, it could have been about any aspect of biology. As it happens, it is largely about recent adaptation of pathogens and their human host. Nine chapters are medically oriented, two are bioinformatics-oriented and one is technological, describing the state of the art in synthetic point mutagenesis. What stands out in this book is the increasing rate at which DNA data has been amassed in the course of the past decade and how knowledge in this vibrant research field is currently being translated in the medical world.

Mutation-Driven Evolution

Mutation-Driven Evolution PDF

Author: Masatoshi Nei

Publisher: OUP Oxford

Published: 2013-05-02

Total Pages: 261

ISBN-13: 0199661731

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The purpose of this book is to present a new theory of mutation-driven evolution, which is based on recent advances in genomics and evolutionary developmental biology. This theory asserts that the driving force of evolution is mutation and natural selection is of secondary importance.

Genetics for Surgeons

Genetics for Surgeons PDF

Author: Patrick John Morrison

Publisher: Remedica

Published: 2005

Total Pages: 237

ISBN-13: 1901346692

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Morrison (human genetics, University of Ulster, UK) and Spence (biomedical science, University of Ulster, UK) offer an accessible reference on the genetic disorders that surgeons can expect to meet in general surgical practice. Written in non-technical language, with a glossary, list of abbreviations, and color and b&w photos and medical images, the book supplies an introduction to the nomenclature and technology of molecular biology, and will be a useful starting point for those who wish to extend their knowledge. Annotation :2005 Book News, Inc., Portland, OR (booknews.com).

Genetic Transformation Systems in Fungi, Volume 2

Genetic Transformation Systems in Fungi, Volume 2 PDF

Author: Marco A. van den Berg

Publisher: Springer

Published: 2014-10-31

Total Pages: 275

ISBN-13: 3319105035

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Fungi are an economic very important class of microbes. Not only do they host a range of versatile enzymes used in industrial applications (biofuels, laundry, food processing), as well do they produce several very important pharmaceutical drugs (statins and penicillins). Moreover, fungal pathogens can cause great damage in agricultural production (Phytophthora and Botrytis) and during mammalian infections (Penicillium marneffei and Candida). Transformation of DNA is used to understand the genetic basis behind these traits. Several different techniques have been developed over the years and readily shown to be decisive methods to improve fungal biotechnology. This book will cover the basics behind the most commonly used transformation methods, as well as associated tools and techniques. Each chapter will provide protocols along with examples to be used in laboratories worldwide.

Novel Approach to Point Mutation

Novel Approach to Point Mutation PDF

Author: David Norman

Publisher:

Published: 2015-03-20

Total Pages: 0

ISBN-13: 9781632390097

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A mutation resulting in a single base nucleotide being replaced by a genetic nucleotide is referred to as point mutation. This text sheds light on the marks left behind in chromosomes by the influencers that propel the DNA code evolution in the form of DNA nucleotide replacements. Since the genetic code is crucial in prior determination of the molecular foundation of existence, it can affect any facet of biology. Incidentally, it is concerned primarily with the evolution of germs and their human hosts. The unique distinction of this text is the rapid pace at which DNA information has been gathered over the past few years and how advancements in this exciting field of study are currently being applied in the medical world.

Handbook of Epigenetics

Handbook of Epigenetics PDF

Author: Trygve Tollefsbol

Publisher: Academic Press

Published: 2017-07-10

Total Pages: 682

ISBN-13: 0128054778

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Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders. Timely and comprehensive collection of fully up-to-date reviews on epigenetics that are organized into one volume and written by leading figures in the field Covers the latest advances in many different areas of epigenetics, ranging from basic aspects, to technologies, to clinical medicine Written at a verbal and technical level that can be understood by scientists and college students Updated to include new epigenetic discoveries, newly approved therapeutics, and clinical trials

Genetic Instabilities and Neurological Diseases

Genetic Instabilities and Neurological Diseases PDF

Author: Robert D. Wells

Publisher: Elsevier

Published: 2011-10-13

Total Pages: 783

ISBN-13: 0080463770

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Genetic Instabilities and Neurological Diseases covers DNA repeat instability and neurological disorders, covering molecular mechanisms of repeat expansion, pathogenic mechanisms, clinical phenotype, parental gender effects, genotype-phenotype correlation, and diagnostic applications of the molecular data. This updated edition provides updates of these repeat expansion mutations, including the addition of many new chapters, and old chapters rewritten as extensions of the previous edition. This book is an invaluable reference source for neuroscientists, geneticists, neurologists, molecular biologists, genetic counsellors and students. Contributions by most of the principal research teams in the area, edited by world-renowned leaders Lays the background for future investigations on related diseases