Play 1.b3!

Play 1.b3! PDF

Author: Ilya Odessky

Publisher: New In Chess,Csi

Published: 2008-09-18

Total Pages: 0

ISBN-13: 9789056912567

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The popularity of the Nimzo-Larsen Attack is largely based on its surprise value, but in fact 1.b3 is one of White's more logical first moves, since by immediately developing his queen's bishop, White aims at undermining the black centre. Odessky, an International Master from Russia, a well-known chess coach and an outstanding chess writer, will amuse and surprise you, but also teach you all the ins and outs of this offbeat system, which has been used by top players like Bobby Fischer and Bent Larsen. A good choice for players who want to avoid the many theoretical landmines of mainline openings and prefer to steer towards an open battle, right from the start.

Oral Bioavailability Assessment

Oral Bioavailability Assessment PDF

Author: Ayman F. El-Kattan

Publisher: John Wiley & Sons

Published: 2017-05-15

Total Pages: 448

ISBN-13: 111891693X

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Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development. • Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability • Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development • Explains how preclinical animal models – used in preclinical testing – and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development • Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS) • Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development

Winning Quickly with 1.b3 and 1...b6

Winning Quickly with 1.b3 and 1...b6 PDF

Author: Ilya Odessky

Publisher: New In Chess

Published: 2020-07-03

Total Pages: 735

ISBN-13: 9056918915

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“I left chess in 2012. I did not touch it for several years. Then I decided to test my strength in Internet blitz. I started from scratch. The board floated before my eyes, and my knee twitched. Less than two months later, I crossed the grandmaster rating mark. My opponents, among them lots of players with a big name, played chess better than me. Surprisingly though, I knew more. On a small island of chess theory, onto which I lured them, I was better equipped. Much better! About 30% of the games ended in wins around the 20th move. A quarter of the games simply ended in mate. In all games, I opened with the moves 1.b3 and 1…b6.” International Master Ilya Odessky is the world’s leading expert on the 1.b3 and 1…b6 chess opening systems. Despite their apparent calm, these openings can get extremely sharp. Now Odessky presents his findings and achievements of recent years. His baffling traps will help you crush your opponents in the opening, with both White and Black. Odessky admits that some of his lines may objectively be somewhat dubious. But in blitz and rapid games they will lead to spectacular play and many surprising wins. Ilya Odessky will entertain, amuse and surprise you in this highly unusual chess opening book full of ultra-romantic chess.

Circadian Pharmacokinetics

Circadian Pharmacokinetics PDF

Author: Baojian Wu

Publisher: Springer Nature

Published: 2020-10-28

Total Pages: 254

ISBN-13: 9811588074

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This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.

Jon Speelman's Best Games

Jon Speelman's Best Games PDF

Author: Jon Speelman

Publisher: Batsford Books

Published: 2014-11-12

Total Pages: 279

ISBN-13: 1849942331

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Mind-bending analysis and instructive comment from a man who has participated in world chess at the very highest levels. World championship candidate and three-times British Champion Jon Speelman annotates the best of his games. He is renowned as a great fighter and analyst, and a highly original player. This book provides entertainment and instruction in abudance.

Progressive Complete Learn To Play Jazz Guitar Manual

Progressive Complete Learn To Play Jazz Guitar Manual PDF

Author: Muzician.com

Publisher: LearnToPlayMusic.com

Published: 2023-03-24

Total Pages: 226

ISBN-13: 9825325364

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For beginner jazz guitarists. Covers all the chords, scales, rhythms and techniques used by great jazz musicians along with an in-depth analysis of improvisation. Also covers comping, chord substitution, harmony and ear training. Contains lots of great licks and solos in a variety of Jazz styles.

Progressive Complete Learn To Play Guitar Chords Manual

Progressive Complete Learn To Play Guitar Chords Manual PDF

Author: Muzician.com

Publisher: LearnToPlayMusic.com

Published: 2023-03-24

Total Pages: 210

ISBN-13: 9825325240

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For beginner guitarists. Everything you wanted to know about Guitar chords, contained within one book. Contains multiple fingering for all types of chords along with a complete system for playing chords and arpeggios along the whole fretboard. An essential guide for guitarists at any level.

Timman's Triumphs

Timman's Triumphs PDF

Author: Jan Timman

Publisher: New In Chess

Published: 2020-09-05

Total Pages: 650

ISBN-13: 9056919180

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Jan Timman is one of the greatest chess players never to win the world title. For many years ‘the Best of the West’ belonged to the chess elite, collecting quite a few super tournament victories. Three times Timman was a Candidate for the World Championship and his peak in the world rankings was second place, in 1982. For this definitive collection, Timman has revisited his career and subjected his finest efforts to fresh analysis supported by modern technology. The result is startling and fascinating. From the games that he chose for his Timman’s Selected Games (1994, also published as Chess the Adventurous Way), only 10(!) made the cut. Some games that he had been proud of turned out to be flawed, others that he remembered as messy were actually well played. Timman’s Triumphs includes wins against great players such as Karpov, Kasparov, Kortchnoi, Smyslov, Tal, Spassky, Bronstein, Larsen and Topalov. The annotations are in the author’s trademark lucid style, a happy mix of colourful background information and sharp, crystal-clear explanations. Once again Jan Timman shows that he is not only one of the best players the game has seen, but also as one of the best chess analysts and writers.

Winning the Won Game

Winning the Won Game PDF

Author: Dr. Danny Kopec

Publisher: Batsford Books

Published: 2015-07-30

Total Pages: 318

ISBN-13: 1849943389

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Every chessplayer who aspires to achieve chess mastery must learn the techniques for winning a won game. It is the perennial problem which confronts players at all levels of play. This book will enable chessplayers to better recognize their positional advantages and the ways in which these can be used in order to bring them closer to victory. It also provides many instructive examples of using this knowledge to reach a faster and more spectacular victory. Mr. Paul M. Albert, Jr. has been donating over $2000 per year to the most brilliantly played at both the Women's and Men's United States Championships for over 20 years. This book presents, describes and illustrates the most significant examples, with emphasis on what can be learned from them in terms of winning a won game.