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Author: F. Albert Cotton
Publisher: Springer Science & Business Media
Published: 2006-07-31
Total Pages: 840
ISBN-13: 0387258299
DOWNLOAD EBOOK →Provides historical perspective as well as current data Abundantly illustrated with figures redrawn from literature data Covers all pertinent theory and physical chemistry Catalytic and chemotherapeutic applications are included
Author: William Deverell
Publisher: ECW Press
Published: 2003-10-03
Total Pages: 221
ISBN-13: 1770905480
DOWNLOAD EBOOK →In this “fast-paced, wickedly funny” legal thriller, a small-town lawyer’s case against a Los Angeles record label turns into a deadly media circus (Publishers Weekly). Living in the Northern California town of Foolsgold, widowed lawyer Oliver Gulliver is headed for a midlife crisis. It doesn’t help that his eighteen-year-old daughter Elora has fallen in love with alcoholic former rock star C.C. Gilley. But then C.C. quits drinking and gets to work on a comeback album. Things actually seem to be looking up—until C.C.’s car is stolen, with his priceless demo tape inside. In no time at all, another band is all over the radio with C.C.’s song, and Oliver finds himself in Los Angeles working the biggest case of his life—suing a billion-dollar record company for plagiarism. But even as Oliver discovers his talent for charming the public, he finds out how nasty the music industry can get. When the stakes skyrocket from plagiarism to murder, Oliver will have to try C.C.’s case like his life depends on it—because it does. “Reeling off witty turns of phrase and uncanny plot twists, Deverell offers wonderfully sardonic takes on the worlds of music, law, Hollywood, Southern California and fatherhood--just for starters.” —Publishers Weekly
Author: Stephen B. Howell
Publisher: Springer Science & Business Media
Published: 2013-11-11
Total Pages: 535
ISBN-13: 1489907386
DOWNLOAD EBOOK →Taken together the data presented in this review, and work by many other investigators, support the notion that DNA excision repair is important in a tumor cell's resistance to platinum compounds. Inhibition of this repair system by combination chemotherapy with the excision repair inhibitors HU and Ara-C produces synergistic cell kills and increased levels and persistance of DNA interstrand crosslinks. The studies with cis-DDP and ~-DDP in combination with UV induced thymine dimers suggest that there may be competition for DNA repair enzymes between the dimer and the platinum lesion. Whether the competing lesion is an intrastrand crosslink, interstrand crosslink, or platinum monoadduct (or all of these lesions) cannot be determined. The similarity between an intrastrand crosslink and a cyclobutane dimer suggests that these lesions may compete for repair. However, the increased peak levels of interstrand crosslinks, and increased persistence of these lesions at later time points suggest that this lesion may also be a substrate for the repair system. These observations may be of clinical relevance. Recently Dr. Kathy Albain of our institution has completed a Phase III I study using a 12 hour pretreatment with HU and Ara-C in patients prior to their cis-DDP therapy. She observed a significant number of responders in this trial (54). She is currently completing a second Phase IIII study substituting IV HU for the oral formulation. We anticipate initiating other clinical trials based upon these observations.
Author: N. Farrell
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 304
ISBN-13: 9401175683
DOWNLOAD EBOOK →When this book was first conceived as a project the expanding interest in the clinical use of platinum and gold complexes made a survey of the relevant biological properties of metal complexes timely and appropriate. This timeliness has not diminished during the gestation and final publica tion of the manuscript. The introduction contains an explanation of the layout and approach to the book, which I wrote as an overall survey of the wide variety of biological properties of metal complexes. Hopefully, the reader will see the parallels in mechanisms and behavior, even in different organisms. The writing was considerably helped by the enthusiasm and confidence (totally unearned on my part) in the project of Professor Brian James and lowe him my special thanks. I also owe a great debt of gratitude to my colleagues, and especially to Eucler Paniago, of the Universidade Federal de Minas Gerais, for their comprehension and for the initial leave of absence which allowed me to begin the project. To those who read some or all of the manuscript and made suggestions, Bernhard Lippert, Kirsten Skov, and Tom Tritton, as well as the editor's reviewer I am also grateful. As usual, the final responsibility for errors or otherwise rests with the author.
Author: Gary J.K. Acres
Publisher: Springer Science & Business Media
Published: 2013-06-29
Total Pages: 356
ISBN-13: 3662102781
DOWNLOAD EBOOK →Like most supplement volumes of the platinum-group metal series,Platinum Suppl. Vol. A 1 has been written by an international team of specialists. It comprises technological data of all six platinum-group metals and their technically relevant alloys and compounds. The volume starts with a review on the recovery of the platinum-group metals (23 pages); the next 42 pages are devoted to processes for separating and refining the PGM in order to obtain metals of high purity. The electrodeposition of the PGM and their alloys is treated on 26 pages.The by far most extensive section deals with PGMand their alloys and compounds in catalysis. After a historicalsurvey and alist of important reviewson PGMcatalysis,the catalytic properties of the metals are treated in a general way, followed by unsupported metals and alloys including preparation of catalysts and their reactions in various industrial processes. The role of supported metals and alloys is described in asimilar manner. This isfollowed byan extensive description of the preparation and the reactions of PGM compounds with various nonmetals and their catalytically active role in a number of industrial processes (226 pages). The last chapter (21 pages) is a compilation of data on the medical use of cytostatic platinum compounds. Gelnhausen, December 1985 Kurt Swars IX Table of Contents Page Technology ofthe Platinum-Group Metals. ............................... 1 1 Review on the Recovery ofthe Platinum-Group Metals . 1.1 Historical Perspective , , , . Period of Discovery, 1750 to 1820 , , . First Industrial Period 1820 to 1900 , , , .
Author: E. Rizzarelli
Publisher: Springer Science & Business Media
Published: 2013-04-17
Total Pages: 231
ISBN-13: 9401136203
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Publisher: Elsevier
Published: 1999-11-11
Total Pages: 444
ISBN-13: 9780080524481
DOWNLOAD EBOOK →Advances in Inorganic Chemistry presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state. This acclaimed serial features reviews written by experts in the area and is an indispensable reference for advanced researchers. Each volume of Advances in Inorganic Chemistry contains an index, and each chapter is fully referenced.
Author: Alaa S. Abd-El-Aziz
Publisher: John Wiley & Sons
Published: 2009-11-02
Total Pages: 565
ISBN-13: 0470251441
DOWNLOAD EBOOK →Volume 9 in a scientific research series, covering macromolecules This book, Macromolecules Containing Metal and Metal-like Elements, presents research developments in the study of: supramolecular chemistry, supramolecular architecture and supramolecular self-assemblies. The topics addressed involve materials containing metals and metal-like elements as well as the possible applications of hybrid materials. The volume offers a broad series of coverage with conclusions and perspectives for the various areas covered.
