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Photothermal Therapy

Author: Paresh Chandra Ray

Publisher:

Published: 2017

Total Pages: 159

ISBN-13: 9781536105759

Editor Biography: Dr. Paresh C Ray, Professor of Chemistry at Jackson State University. His research group is heavily involved in cancer nanotechnology research that include development of new assay for CTCs detection from blood, exploring new chemical strategies for the multi-photon imaging and multimodal therapy of cancer cell, designing multifunctional nanomaterial for developing nanomedicine, and enhancing our understanding of biomolecular interaction with nanosurface. He has been author/co-author for over 160 peer-reviewed publications in international and national renowned journals. His group's work has been widely cited with h-index 49. He holds several US pending patent. His research has been funded by National Science Foundation, National Institute of Health, Army Research Office, Army Research Lab, Universal Technology Corporation. Book Description: Cancer metastasis is one of the greatest challenges for our society and is responsible for over 90% of cancer-related deaths. Even in the 21st century, currently available therapies have very limited curative effects for metastatic cancers patients, where the five-year survival rate is only about 20%. Our society needs rapid, sensitive, and reliable cancer therapy which will help save millions of lives every year worldwide. There is no doubt that the development of nano-material based targeted therapy techniques are fast growing research areas for oncology, nanomedicine, chemistry, biology, biomedical engineering and other disciplines. Photo-thermal therapy is a minimally-invasive targeted therapy using bio-conjugated nanoparticles, in which photon energy is converted into heat to kill cancer. Over the last ten years, society has experienced a tremendous growth in the development and implementation of photothermal therapy for cancer. To summarize the recent growth, the first volume in the Photothermal Therapy: Mechanisms, Efficiency and Future Directions series discusses the development of different nanomaterial based photothermal therapy, which have the capability for targeted therapy using near infrared (NIR) light. It contains six chapters written by renowned experts in this area, covering from basic science to possible device design which can have immense applications in our society. This book is unique in its design and content, providing an in depth analysis of this scientific field to elucidate molecular mechanisms of photothermal therapy, engineering design for targeted therapy and the latest research on evolving therapeutic technology to tackle the challenges society is facing now due to cancer and other diseases. The readers will be very pleased to read the wide range of state-of-the-art targeted therapeutic techniques, which have been developed for targeted photo-therapy of cancer, drug resistance bacteria and viruses. Target Audience: The best audience will be students and faculties from academic institute. Doctors and medical students from medical schools also will be the buyer for this book. Employers from medical industry will be interested to find the latest technology for cancer therapy.

Mechanisms of Cell Death

Author: Zahra Zakeri

Publisher:

Published: 1999

Total Pages: 236

ISBN-13:

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Contains papers from a July 1998 conference held at the Queens College Campus of the City University of New York. Papers are arranged in sections on mechanisms and general considerations, programmed (developmental) cell death, and cell death and pathological and clinical situations. Specific topics

Gold Nanoparticles in Biomedical Applications

Author: Lev Dykman

Publisher: CRC Press

Published: 2017-12-12

Total Pages: 430

ISBN-13: 1351360477

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This book discusses fabrication of functionalized gold nanoparticles (GNPs) and multifunctional nanocomposites, their optical properties, and applications in biological studies. This is the very first book of its kind to comprehensively discuss published data on in vitro and in vivo biodistribution, toxicity, and uptake of GNP by mammalian cells providing a systematization of data over the GNP types and parameters, their surface functionalization, animal and cell models. As distinct from other related books, Gold Nanoparticles in Biomedical Applications discusses the immunological properties of GNPs and summarizes their applications as an antigen carrier and adjuvant in immunization for the preparation of antibodies in vivo. Although the potential of GNPs in nanobiotechnology has been recognized for the past decade, new insights into the unique properties of multifunctional nanostructures have recently emerged. With these developments in mind, this book unites ground breaking experimental data with a discussion of hybrid nanoparticle systems that combine different nanomaterials to create multifunctional structures. These novel hybrids constitute the material basis of theranostics, bringing together the advanced properties of functionalized GNPs and composites into a single multifunctional nanostructure with simultaneous diagnostic and therapeutic functions. Such nanohybrids can be physically and chemically tailored for a particular organ, disease, and patient thus making personalized medicine available.

Recent Trends in Cancer Therapeutics

Author: Divya Khurana

Publisher: Springer Nature

Published: 2024

Total Pages: 185

ISBN-13: 9819998794

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Zusammenfassung: This book describes the plasmonic photothermal-assisted multimodal cancer therapeutics in the area of cancer nanotechnology or cancer nanomedicine. This book covers the fundamentals of plasmonic photothermal cancer therapy as well as plasmonic photothermal mediated multimodal cancer therapy. The various steps involved in developing such therapeutic modality, viz. (a) the selection of suitable nanoparticles, (b) synthesis of multifunctional nanocomposite, (c) optimization of the photosensitizer and chemotherapeutic drug loadings, (d) characterization of the synthesized nanocomposite, and (e) therapeutic evaluations through novel tumor-tissue mimicking phantoms and the cancer cell lines are discussed in detail. Apart from the detailed description of therapeutic outcome, this book provides a step-by-step approach to develop a multifunctional nanocomposite for such therapeutics. Overall, this book provides simplified and in-depth information about cancer nanobiotechnology to the researchers and graduate students in subject areas of nanotechnology, biotechnology and pharmaceutics to develop and contribute to such multimodal cancer therapeutics

Nano Drug Delivery Strategies for the Treatment of Cancers

Author: Awesh K. Yadav

Publisher: Academic Press

Published: 2020-09-03

Total Pages: 374

ISBN-13: 0128197943

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Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field. Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies Provides foundational information on different types of cancer and their biology to help the reader choose the best nano drug delivery system for patients Presents novel drug delivery systems based on nanoparticles, microparticles, liposomes, self-assembling Micelles and block copolymer micelles

Nanostructures for Oral Medicine

Author: Ecaterina Andronescu

Publisher: Elsevier

Published: 2017-04-11

Total Pages: 1036

ISBN-13: 0323477216

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Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices

Nanoscience in Dermatology

Author: Michael R. Hamblin

Publisher: Academic Press

Published: 2016-08-13

Total Pages: 404

ISBN-13: 0128029455

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Nanoscience in Dermatology covers one of the two fastest growing areas within dermatological science, nanoscience and nanotechnology in dermatology. Recently, great progress has been made in the research and development of nanotechnologies and nanomaterials related to various applications in medicine and, in general, the life sciences. There is increasing enthusiasm for nanotechnology applications in dermatology (drug delivery, diagnostics, therapeutics, imaging, sensors, etc.) for understanding skin biology, improving early detection and treatment of skin diseases, and in the design and optimization of cosmetics. Light sensitive nanoparticles have recently been explored, opening a new era for the combined applications of light with nanotechnology, also called photonanodermatology. However, concerns have been raised regarding the adverse effects of intentional and unintentional nanoparticle exposure and their toxicity. Written by experts working in these exciting fields, this book extensively covers nanotechnology applications, together with the fundamentals and toxicity aspects. It not only addresses current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing scientists and dermatologists with a clear understanding of the advantages and challenges of nanotechnology in skin medicine. Provides knowledge of current and future applications of nanoscience and nanotechnology in dermatology Outlines the fundamentals, methods, toxicity aspects, and other relevant aspects for nanotechnology based applications in dermatology Coherently structured book written by experts working in the fields covered

Photothermal Nanomaterials

Author: Enyi Ye

Publisher: Royal Society of Chemistry

Published: 2022-01-18

Total Pages: 359

ISBN-13: 1839165189

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The exploration of photothermal nanomaterials with high light-to-heat conversion efficiency has paved the way for practical applications, including in cancer therapy, environmental remediation, catalysis, imaging and biomedicine. Covering the photothermal effect of different categories of light-absorbing nanomaterials, and focusing on metallic nanomaterials, 2D materials, semiconductors, carbon-based nanomaterials, polymeric nanomaterials and their composites, chapters in this book provide a systematic summary of recent advances in the fabrication and application of photothermal nanomaterials, discussing advantages, challenges and potential opportunities. This text will be a valuable resource for scientists working on photothermal nanomaterials, as well as those interested in the applications across chemistry, biomedicine, nanotechnology and materials science.

Gold Nanostars

Author: Giuseppe Chirico

Publisher: Springer

Published: 2015-08-03

Total Pages: 93

ISBN-13: 3319207687

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This Brief focuses on the synthesis, functionalization techniques, optical properties and biomedical application of gold nanostars (GNS). Various facilities of gold nanostars synthesis as well as functionalization of GNS with PEG, organic dyes, bioactive compounds are discussed. The authors discuss physical origin of the Localized Surface Plasmon Resonances and the way the nano-environment affects them. The implication of the LSPR of gold nanostars surface enhanced Raman scattering is also discussed. The emphasis has been done on the application of GNS for current and emerge needs of medicine, biology and pharmacy. Moreover, properties of gold nanostars as contrast agents for in vivo imaging and interaction of GNS with cells are also discussed in this Brief.

Near Infrared-Emitting Nanoparticles for Biomedical Applications

Author: Antonio Benayas

Publisher: Springer Nature

Published: 2020-04-13

Total Pages: 391

ISBN-13: 3030320367

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This book analyzes and evaluates the growing field of light-emitting nanoprobes as contrast agents for in vivo imaging and sensing. It is a comprehensive resource that critically analyzes the state of the art in an interdisciplinary manner, with a special focus on the shift of emission wavelengths into the near-infrared (NIR) spectral region (ranging from 0.7 to 2 microns), which has greatly contributed to the latest advances in biomedical imaging and sensing. This book discusses merits of different contrast agents at nanoscale, and how their unique chemical and structural properties lead to the emission and interaction of light within the NIR window. Both the NIR-emitting materials and various surface modification strategies governing their interactions with the biological system at the “nano” level are discussed. Furthermore, different experimental techniques and protocols for NIR-light-based in vivo imaging and sensing are addressed to shed light on further understanding of the advantages and limitations of each category of these nanoprobes. Assembles the state of the art heretofore appearing in scientific literature into a comprehensive, multi-perspective guidebook on near infrared-emitting nanomaterials in an assortment of biomedical applications; Explains the physical, chemical, and biological phenomena underlying near infrared-emitting nanomaterials for biomedical applications; Presents conceptual and experimental approaches surrounding a unique spectral range of light emission from nanosized contrast agents, while offering a clear explanation of basic and general phenomena regarding the interaction between light and biological tissues, such as absorption, scattering and autofluorescence.