Pharmaceutical Strategies to Prevent, Treat, and Recover: Advances and Challenges in Ischemic Stroke and Hemorrhagic Stroke

Pharmaceutical Strategies to Prevent, Treat, and Recover: Advances and Challenges in Ischemic Stroke and Hemorrhagic Stroke PDF

Author: Yuwen Li

Publisher: Frontiers Media SA

Published: 2024-03-01

Total Pages: 218

ISBN-13: 2832545432

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Stroke is one of the leading causes of death and disability worldwide. Among them, ischemic stroke is attributed to an abrupt blockage of blood flow to brain, while hemorrhagic stroke is caused by bleeding into brain. The principal aim of stroke therapy is to decrease mortality and reduce persistent neurologic injury and long-term disability. It also targets to prevent complications and recurrence after stroke as well as minimize the brain function loss caused by the cerebral damage. Fortunately, many strokes could be prevented through healthy lifestyle changes and controlling stroke risk factors, such as cigarette or tobacco smoking, high blood pressure, diabetes, and heart disease. Carotid endarterectomy and stenting of the cervical and intracranial vessels may help reduce recurrent stroke in some cases. Advanced treatments and rehabilitation are helping many stroke patients return to society and their families.

Ischemic Stroke Therapeutics

Ischemic Stroke Therapeutics PDF

Author: Bruce Ovbiagele

Publisher: Springer

Published: 2015-11-24

Total Pages: 321

ISBN-13: 3319177508

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This complete resource captures state-of-the-art strategies and the accelerated pace of discovery that is revolutionizing what is known about ischemic stroke and its treatment. Therapeutics for acute management, secondary prevention, recovery, rehabilitation, asymptomatic cerebral ischemia, and implementation of stroke systems of care are all discussed in this comprehensive yet practical guide. Chapters are authored by leading academicians with extensive clinical practice experience from all over the world and feature the scientific evidence behind prevailing therapeutic strategies for managing ischemic cerebrovascular disease. The specialist or general practitioner will gain critical knowledge in stroke management, current clinical challenges and promising new therapies under investigation.

Acute Ischemic Stroke

Acute Ischemic Stroke PDF

Author: R. Gilberto González

Publisher: Springer Science & Business Media

Published: 2010-10-05

Total Pages: 299

ISBN-13: 3642127517

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This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.

Disease Control Priorities, Third Edition (Volume 5)

Disease Control Priorities, Third Edition (Volume 5) PDF

Author: Dorairaj Prabhakaran

Publisher: World Bank Publications

Published: 2017-11-17

Total Pages: 466

ISBN-13: 1464805202

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Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Stroke Therapy

Stroke Therapy PDF

Author: Marc Fisher

Publisher: Butterworth-Heinemann

Published: 2001

Total Pages: 432

ISBN-13:

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This new edition keeps you up to date with the exciting new developments in treating cerebrovascular disorders. Comprehensive and practical, it surveys methods for accurate stroke diagnosis necessary for you to make appropriate therapeutic decisions.

Precision Medicine in Stroke

Precision Medicine in Stroke PDF

Author: Ana Catarina Fonseca

Publisher: Springer Nature

Published: 2021-05-04

Total Pages: 339

ISBN-13: 303070761X

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This book provides a comprehensive coverage of the state of the art in precision medicine in stroke. It starts by explaining and giving general information about precision medicine. Current applications in different strokes types (ischemic, haemorrhagic) are presented from diagnosis to treatment. In addition, ongoing research in the field (early stroke diagnosis and estimation of prognosis) is extensively discussed. The final part provides an in-depth discussion of how different interdisciplinary areas like artificial intelligence, molecular biology and genetics are contributing to this area. Precision Medicine in Stroke provides a practical approach to each chapter, reinforcing clinical applications and presenting clinical cases. This book is intended for all clinicians that interact with stroke patients (neurologists, internal medicine doctors, general practitioners, neurosurgeons), students and basic researchers.

Cerebral Small Vessel Disease

Cerebral Small Vessel Disease PDF

Author: Leonardo Pantoni

Publisher: Cambridge University Press

Published: 2014-05

Total Pages: 375

ISBN-13: 1107031664

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Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.

Management of Subarachnoid Hemorrhage

Management of Subarachnoid Hemorrhage PDF

Author: Adel E. Ahmed Ganaw

Publisher: Springer Nature

Published: 2021-11-26

Total Pages: 227

ISBN-13: 3030813339

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This book focuses on subarachnoid hemorrhage (SAH), describing in detail the neurophysiology, anatomy, epidemiology, grading, anesthesia management, coiling and interventional treatment of this dangerous disease. Written by leading international experts, it highlights the state-of-the-art techniques for the diagnosis and treatment (non-surgical and surgical) of SAH and the clinical variations. It also examines the reliability of the new techniques versus the standard clinical methods to predict problems related to SAH and its recent diagnosis and management. The book starts with a brief discussion of the epidemiology of SAH, cerebral circulation, anatomy of brain blood vessels and neurophysiology related to this fatal disease. Then, in the following chapters it covers grading of subarachnoid hemorrhage, anesthesia management of SAH, treatment, subarachnoid hemorrhage coiling and radiological intervention. Lastly, it explores surgical treatment of intracranial aneurysms in more detail, and addresses complications, critical care management and headache in SAH, traumatic SAH and prognosis. Featuring numerous images, tables, schema, illustrations and videos, the book is intended for junior and senior anesthesiologists, neuroscientists, intervention radiologists, intensivists and neurosurgeons.

Translational Research in Stroke

Translational Research in Stroke PDF

Author: Paul A. Lapchak

Publisher: Springer

Published: 2017-12-20

Total Pages: 581

ISBN-13: 9811058040

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This book mainly discusses the current status of stroke transnational research and allows the reader to understand the interplay of common comorbidities in the stroke population such as diabetes and hypertension, and provides insight into stroke targets to promote cell survival, angiogenesis, neurogenesis, and most importantly, functional recovery after stroke. Throughout the world, stroke is still a leading cause of mortality and morbidity; each year approximately 15 million people worldwide suffer from stroke. Stroke is now the leading cause of death and disability in China. Large communities of stroke survivors are eagerly awaiting scientific advances in transnational stroke research that would offer neuroprotective therapeutics for acute stroke management, or rehabilitation and regenerative strategies utilizing novel stem cell-based approaches. While research is ongoing, the Editors have compiled this volume to help the further understanding of the pathophysiology of stroke and to review and identify future potential biomarkers. The book is written for students, researchers and physicians in neurosciences, neurology and neuroradiology.

Neurological, Psychiatric, and Developmental Disorders

Neurological, Psychiatric, and Developmental Disorders PDF

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-01-01

Total Pages: 458

ISBN-13: 0309170931

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Brain disordersâ€"neurological, psychiatric, and developmentalâ€"now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.