Perspective of tumor heterogeneity for treatments of intrahepatic cholangiocarcinoma with intrahepatic lithiasis

Perspective of tumor heterogeneity for treatments of intrahepatic cholangiocarcinoma with intrahepatic lithiasis PDF

Author: Wenjie Hou

Publisher: OAE Publishing Inc.

Published: 2023-07-31

Total Pages: 5

ISBN-13:

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The heterogeneity of tumors results in significantly distinct biological characteristics of intrahepatic cholangiocarcinoma (ICC) caused by different etiologies. Among them, ICC caused by intrahepatic lithiasis (IHL-ICC) presents challenges in early detection, tumor staging, and surgical treatment, and has the poorest prognosis among all etiologies of ICC patients. Thus, it is essential to focus on early assessment of the possibility of developing ICC, prompt intervention of intrahepatic lithiasis, anatomical resection of hepatic parenchyma corresponding to the branch of the intrahepatic bile duct undergoing cancerous transformation, and enhanced postoperative follow-up of hepatolithiasis and ICC for IHL-ICC patients. These interventions are crucial to improve the clinical outcomes and overall survival of IHL-ICC patients.

Hepatobiliary Surgery

Hepatobiliary Surgery PDF

Author: Ronald S. Chamberlain

Publisher: CRC Press

Published: 2003-01-01

Total Pages: 286

ISBN-13: 1498712940

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This book is written as a reference and guidebook for practicing surgeons, gastroenterologists, and interventional radiologists with an interest in hepatobiliary diseases. It presents a strategy to enhance surgeons practice and the care of patients.

Gastrointestinal Malignancies

Gastrointestinal Malignancies PDF

Author: David Bentrem

Publisher: Springer

Published: 2024-08-15

Total Pages: 0

ISBN-13: 9783031612374

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This book now published in its fully updated second edition comprehensively summarizes the current state of knowledge on malignancies of the gastrointestinal tract and highlights the latest efforts in multimodality treatment options before and after surgery, important ongoing trials as well as future areas of investigation. Dedicated organ-based chapters evaluate current treatments and management and provide information on incidence, etiology and biological characteristics. The state of the art in the radiologic and endoscopic staging of gastrointestinal malignancies is described, and guidance is offered on the role of interventional radiology and interventional gastroenterology in the treatment of these challenging tumors. In addition, the book explores novel and evolving treatments, including Immunotherapy, personalized systemic therapy and minimally invasive surgical and radiology techniques, and addresses patient-reported outcomes and survivorship challenges. It will be of benefit to all surgeons, oncologists and other specialists who treat these malignancies, as well as to trainees looking to increase their understanding of the field.

IgG4-Related Sclerosing Cholangitis

IgG4-Related Sclerosing Cholangitis PDF

Author: Terumi Kamisawa

Publisher: Springer

Published: 2018-07-31

Total Pages: 142

ISBN-13: 9811045488

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This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.

Diagnosis and Management of Cholangiocarcinoma

Diagnosis and Management of Cholangiocarcinoma PDF

Author: James H. Tabibian

Publisher: Springer Nature

Published: 2021-05-28

Total Pages: 589

ISBN-13: 3030709361

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This book provides a comprehensive, state-of-the-art overview of cholangiocarcinoma (CCA). The text is structured to effectively present a broad yet concise overview of bile duct cancer, its relevant definitions, classification schemata, clinical management tenets, translational (including molecular and cellular) facets, and future directions. The book features numerous high-yield illustrations and is authored by an eclectic range of renowned experts in various areas of CCA, reflecting the multidisciplinary nature of the field. Filling a critical gap in the field, Diagnosis and Management of Cholangiocarcinoma: A Multidisciplinary Approach is a valuable resource for clinicians and practitioners who treat patients with bile duct cancer.

Biliary Tract and Gallbladder Cancer

Biliary Tract and Gallbladder Cancer PDF

Author: Joseph M. Herman

Publisher: Springer Science & Business Media

Published: 2014-03-21

Total Pages: 345

ISBN-13: 3642405584

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The second edition of this book is intended as a definitive text on biliary tract and gallbladder cancers. Specifically, it will serve as a single-source reference on the current knowledge base for the multidisciplinary management of such cancers and thus covers epidemiological, surgical, radiotherapy, and chemotherapy approaches. A key feature is the demonstration of the impact of cutting-edge technical knowledge on treatment; for example, interventional radiology techniques, novel surgical approaches, and image-guided radiation therapy are all extensively discussed. Diagnosis is also considered in detail, with coverage of novel serum biomarkers, pathologic staging, molecular profiling, and the full range of current and emerging imaging strategies. This book will be an invaluable source of information on new techniques for experienced practitioners, yet is sufficiently concise to offer an introduction to the field for students and community practitioners.

Liver Disease in Children

Liver Disease in Children PDF

Author: Frederick J. Suchy

Publisher: Cambridge University Press

Published: 2021-03-18

Total Pages: 875

ISBN-13: 1108911374

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Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.

Abdominal-Pelvic MRI

Abdominal-Pelvic MRI PDF

Author: Richard C. Semelka

Publisher: John Wiley & Sons

Published: 2011-09-26

Total Pages: 2734

ISBN-13: 1118211383

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This landmark reference provides the most complete coverage of magnetic resonance imaging of the abdomen and pelvis, with particular emphasis on illustrating benign, malignant, and inflammatory lesions. Organized by anatomic region, the text presents brief descriptions of pathophysiology followed by detailed discussion of characteristics of the relevant organ or system. Extensively updated and revised throughout, the new third edition includes over 2,500 figures, of which more than 500 are all-new, including over 200 3T images presented throughout the organ systems. Two all-new chapters are also included, one discussing MRI in pregnancy, and another on MRI of the Breast.

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