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Personalized Medicine in the Making

Author: Chiara Beneduce

Publisher: Springer Nature

Published: 2022-03-07

Total Pages: 334

ISBN-13: 3030748049

This book offers a multidisciplinary look at the much-debated concept of “personalized medicine”. By combining a humanistic and a scientific approach, the book builds up a multidimensional way to understand the limits and potentialities of a personalized approach in medicine and healthcare. The book reflects on personalized medicine and complex diseases, the relationship between personalized medicine and the new bio-technologies, personalized medicine and personalized nutrition, and on some ethical, political, economic, and social implications of personalized medicine. This volume is of interest to researchers from several disciplines including philosophy, bio-medicine, and the social sciences. Chapter 16, “The Impact of Fantasy” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Textbook of Personalized Medicine

Author: Kewal K. Jain

Publisher: Humana Press

Published: 2015-03-17

Total Pages: 762

ISBN-13: 1493925539

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Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.

Can Precision Medicine Be Personal; Can Personalized Medicine Be Precise?

Author: Yechiel Michael Barilan

Publisher: Oxford University Press

Published: 2022

Total Pages: 353

ISBN-13: 0198863462

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The book provides a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision / personal medicine, involving scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science.

Can precision medicine be personal; Can personalized medicine be precise?

Author: Y. Michael Barilan

Publisher: Oxford University Press

Published: 2022-02-10

Total Pages: 353

ISBN-13: 0192608681

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People have always sought medical care that is tailored to every individual patient. Alongside with the historical development of institutions of care, the vision of personal and 'holistic' care persisted. Patient-centred medicine, interpersonal communication and shared decision making have become central to medical practice and services. This evolving vision of 'personalized medicine' is in the forefront of medicine, creating debates among ethicists, philosophers and sociologists of medicine about the nature of disease and the definition of wellness, the impact on the daily life of patients, as well as its implications on low-income countries. Is increased 'precision' also an improvement on the personal aspects of care or erosion of privacy? Do 'precise' and 'personalized' approach marginalize public health, and can this care be personalized without attention to culture, economy and society? The book provides a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision/personal medicine, involving scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science. The contributing scholars come from all over the world and from different cultural backgrounds providing reflective perspectives of history of ideas, critical theory and technology assessment, together with the actual work done by pioneers in the field. It explores issues such as global justice, gender, public health, pharmaceutical industry, international law and religion, and explores themes discussed in relation to personalized medicine such as new-born screening and disorders of consciousness. This book will be of interest to academicians in bioethics, history of medicine, social sciences of medicine as well as general educated readers.

Progress and Challenges in Precision Medicine

Author: Mukesh Verma

Publisher: Academic Press

Published: 2016-12-22

Total Pages: 344

ISBN-13: 0128095024

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Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

P5 eHealth: An Agenda for the Health Technologies of the Future

Author: Gabriella Pravettoni

Publisher: Springer Nature

Published: 2019-11-29

Total Pages: 191

ISBN-13: 3030279944

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This open access volume focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design. It provides practical guidelines and evidence based examples on how to design, implement, use and elevate new technologies for healthcare to support the management of incurable, chronic conditions. The volume further discusses the criticalities of eHealth, why it is difficult to employ eHealth from an organizational point of view or why patients do not always accept the technology, and how eHealth interventions can be improved in the future. By dealing with the state-of-the-art in eHealth technologies, this volume is of great interest to researchers in the field of physical and mental healthcare, psychologists, stakeholders and policymakers as well as technology developers working in the healthcare sector.

An Immense New Power to Heal

Author: Lee Gutkind

Publisher: Underland Press

Published: 2012-03-23

Total Pages: 242

ISBN-13: 1937163075

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Is personalized medicine—what some scientists call genetic medicine—a pipe dream or a panacea? Francis Collins, current director of the National Institutes of Health and director of the Human Genome Project, considers this new era “the greatest revolution since Leonardo,” while Nobel Laureate Leland Hartwell compares personalized medicine to a train that has not yet left the station—“a very slow train with a very long way to go . . . before we arrive at our destination.” There is no denying that new technology, which has triggered an explosion of scientific information, is ushering in a revolution in medicine—for specialists, general practitioners and the public. Anyone can spit in a cup and, for a small fee, learn about his or her individual genetic make-up. But how useful is this information, really, to us or to our doctors? What’s more, how much do we truly want to know—and have others know—about our possible destiny? There is more than we can imagine at stake. In An Immense New Power to Heal, authors Lee Gutkind and Pagan Kennedy delve into the personal side of personalized medicine and offer the physician’s perspective and the patient’s experience through intimate narratives and case studies. They also offer an intriguing background of the personalized medicine movement including the fascinating personalities of the key scientists involved as well as a glimpse into the in-fighting that accompanies any race for a scientific breakthrough. The result is a highly engaging, lively, and provocative discussion about this revolution in health care, and most importantly, what it really means for patients now and in the future.

Personalised Cancer Medicine

Author: Anne Kerr

Publisher:

Published: 2021-02-23

Total Pages: 280

ISBN-13: 9781526141026

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Economic Dimensions of Personalized and Precision Medicine

Author: Ernst R. Berndt

Publisher: University of Chicago Press

Published: 2019-04-22

Total Pages: 361

ISBN-13: 022661106X

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Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.

Realizing the Promise of Precision Medicine

Author: Paul Cerrato

Publisher: Academic Press

Published: 2017-08-24

Total Pages: 218

ISBN-13: 0128116366

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Realizing the Promise of Precision Medicine: The Role of Patient Data, Mobile Technology, and Consumer Engagement explains the potential of personalized medicine and the value of those approaches in making that potential a reality. The book helps transform one-size-fits-all healthcare into a system that focuses on individual needs and the unique needs of each family member, discussing topics such as U.S. sponsored precision medicine initiative, genomics, the role of electronic health records and mobile medicine, patient engagement and empowerment, health information exchange and patient data protection. In addition, the book discusses the barriers and limitations of precision medicine and how to overcome them. Readers will find valuable insights into how big data, patient engagement, mobile technology, and genomics help individualize medical care and offer a pathway to help detect many undiscovered causes of diseases. Provides drawings and flow charts to help readers visualize the breadth and depth of precision medicine Includes sidebars with more details on specific topics for a complementary, deeper understanding of the main text Uses case studies to turn abstract concepts into flesh and blood examples of how personalized medicine benefits patients