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The Multi-Organ Donor: A Guide to Selection, Preservation and Procurement

Author: Robert S.D. Higgins

Publisher: Bentham Science Publishers

Published: 2018-11-30

Total Pages: 216

ISBN-13: 1681087561

Advances in the science of immunology have improved the success rate of organ transplantations since the mid twentieth century. Organ transplantation is now a lifesaving medical procedure for thousands of patients around the world with end-organ diseases. The lifesaving potential of transplantation has been limited by the number and quality of appropriate organ donors. The evolution of brain death criteria by the Harvard Ad-Hoc Committee Report has opened the door to understanding the importance of medical, legal and ethical challenges of organ donation in support of the growth of the transplant science. The possibility of organ donation from living donors has enhanced organ availability for patients with kidney failure. Modern inotropes and immunosuppression regimens have been critical to the success of other organ transplant procedures. However, the cornerstone of successful transplantation continues to be the appropriate selection, evaluation, preservation of organ tissues and the successful surgical procurement process to mitigate the impact of tissue ischemia and reperfusion. In this textbook, the art and science of organ donation and tissue preservation is examined. Through this authoritative text by leaders in the field, the editors provide a state of the art review of modern preservation techniques, patient selection and screening criteria, as well as best practices for multi-organ procurement. Information presented in the book will familiarize readers with the initial steps of determining organ availability which ultimately enables health care professionals to realize the extraordinary potential of successful multi-organ transplant procedures. This guide is intended to be a fundamental resource for students, residents, faculty and staff for all disciplines allied to health care delivery and organ donation.

Procurement, Preservation and Allocation of Vascularized Organs

Author: G.M. Collins

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 373

ISBN-13: 9401154228

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At the brink of the third millennium organ transplanta mati on how, in the case of shortage, a fair allocation of tion will become routine and the results will be so ex the scarce organs can be achieved. This is a very cellent that every patient in need of a transplant timely subject that continues to be discussed between deserves to be transplanted. How to provide every doctors and between laymen. patient with his or her organ and how to guarantee This book serves the needs of several groups of that the organ is in a superb condition? That is the specialists working with transplant patients. Firstly, the challenge for all of us privileged to work in this doctors who are directly involved in the care of the magnificent field of medicine. multi-organ donor, and who have to collaborate to do In this book, an international team of experts has the best for their recipients. Heart surgeons might like laid down their intellectual knowledge on the process to learn from liver surgeons and vice versa. Secondly, that precedes successful transplantation: Procurement, the paramedical specialist who is involved in the treat Preservation and Allocation. In four sections important ment of transplant patients and their families will find aspects of this preamble of the actual transplantation in this book many answers to questions. Students can are dealt with. also use it as a source for general information.

Organ Preservation for Transplantation

Author: Luis Horacio Toledo-Pereyra

Publisher: CRC Press

Published: 2010-01-18

Total Pages: 264

ISBN-13: 1498713831

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Organ Procurement and Preservation for Transplantation

Author: Luis H. Toledo-Pereyra

Publisher: Springer Verlag

Published: 1997-01-01

Total Pages: 227

ISBN-13: 9783540630760

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Discusses issues involved with organ procurement and preservation for transplantation including donor procurement criteria, perfusion and storage techniques, cryopreservation, ischemia/reperfusion injury and metabolic regulation. This book covers the kidney, liver, pancreas, small bowel, heart and lung, and informs the reader about preservation and procurement developments in the field of transplantation.

Non-Heart-Beating Organ Transplantation

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1998-01-18

Total Pages: 103

ISBN-13: 0309064244

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Non-heart-beating donors (individuals whose deaths are determined by cessation of heart and respiratory function rather than loss of whole brain function) could potentially be of major importance in reducing the gap between the demand for and available supply of organs for transplantation. Prompted by questions concerning the medical management of such donorsâ€"specifically, whether interventions undertaken to enhance the supply and quality of potentially transplantable organs (i.e. the use of anticoagulants and vasodilators) were in the best interests of the donor patientâ€"the U.S. Department of Health and Human Services asked the Institute of Medicine to examine from scientific and ethical points of view "alternative medical approaches that can be used to maximize the availability of organs from [a] donor [in an end-of-life situation] without violating prevailing ethical norms...." This book examines transplantation supply and demand, historical and modern conceptions of non-heart-beating donors, and organ procurement organizations and transplant program policies, and contains recommendations concerning the principles and ethical issues surrounding the topic.

Organ Procurement and Preservation for Transplantation

Author: Luis H. Toledo-Pereyra

Publisher: R G Landes Company

Published: 1997-01-01

Total Pages: 227

ISBN-13: 9781570594502

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Organ Procurement and Preservation

Author: Goran B. Klintmalm

Publisher: CRC Press

Published: 1999-01-01

Total Pages: 174

ISBN-13: 1498713262

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This handbook is a ready reference guide for organ procurement and preservation. Procurement coordinators, surgeons, residents and other health care professionals involved in organ retrieval will find most questions answered that will arise during their participation with these difficult and complex issues. This handbook will prove an invaluable re

Multiorgan Procurement for Transplantation

Author: Paolo Aseni

Publisher: Springer

Published: 2016-02-25

Total Pages: 266

ISBN-13: 3319284169

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This well-illustrated handbook provides answers to important questions that may arise during the retrieval of multiple organs for transplantation and offers step-by-step descriptions of current surgical techniques for procurement of the various thoracic and abdominal organs, including heart, lung, liver, intestine, pancreas, and kidney. The coverage includes detailed instruction on liver splitting techniques and on living donor liver hepatectomies and laparoscopic and robot-assisted nephrectomy for transplantation. In addition, guidance is provided on preoperative evaluation for multiorgan donation, contraindications, management for organ retrieval in deceased donors, and organ preservation. The advice offered and the questions addressed will be of relevance not only to transplant surgeons, trainees, and fellows but also to all other professionals involved in organ transplantation, including nursing staff in intensive care units and emergency rooms.

Contemporary Heart Transplantation

Author: Linda Bogar

Publisher: Springer

Published: 2020-09-10

Total Pages: 0

ISBN-13: 9783319580531

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This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.

Organ Preservation for TransplantationThird Edition

Author: Luis Horacio Toledo-Pereyra

Publisher: CRC Press

Published: 2010-01-18

Total Pages: 264

ISBN-13: 9781587063374

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The first edition of this book, Basic Concepts in Organ Procurement, Perfusion and Preservation for Transplantation, was published 27 years ago, in 1982 when organ procurement and preservation began to advance in the study of the best ways to preserve organs for transplantation. The second edition, Organ Procurement and Preservation for Transplantation, 2nd Edition, followed 15 years later, in 1997, with the goal of finding common denominators in the best preservation techniques for transplantation. In this current third edition, 11 years after the second edition, similar goals are still pursued of defining the best preservation methods, but there is now more evidence, including results, and new advances have reached publication and are being incorporated into ischemia and reperfusion techniques and organ preservation studies. Many preservation solutions have been introduced, important preservation solution components have been better defined, and improved perfusion methods are being considered, especially for the increasing number of organ donors with non-beating hearts who are being sought for transplantation. This edition (2009) engaged experts in the field of organ preservation to review, update, and rewrite each of the chapters. Crafted in collaboration with Luis H. Toledo-Pereyra, the text is eminently informative and easily understandable. Each solid organ that can be transplanted has an entire chapter devoted to the particular methods of its preservation. One chapter apiece, in other words, features insights on the preservation of the kidney, the liver, the pancreas, the small bowel, the heart, and the heart-lung. The title of the present book has been shortened to better represent its content. Thus, Organ Preservation for Transplantation, 3rd Edition, demonstrates a more accurate depiction of its current status. Nevertheless, the goal of this book remains exactly the same as in the first edition, that is “to analyze the most important aspects of organ procurement, perfusion and preservation for transplantation”.