Optimal Mixture Experiments

Optimal Mixture Experiments PDF

Author: B.K. Sinha

Publisher: Springer

Published: 2014-05-24

Total Pages: 213

ISBN-13: 8132217861

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​The book dwells mainly on the optimality aspects of mixture designs. As mixture models are a special case of regression models, a general discussion on regression designs has been presented, which includes topics like continuous designs, de la Garza phenomenon, Loewner order domination, Equivalence theorems for different optimality criteria and standard optimality results for single variable polynomial regression and multivariate linear and quadratic regression models. This is followed by a review of the available literature on estimation of parameters in mixture models. Based on recent research findings, the volume also introduces optimal mixture designs for estimation of optimum mixing proportions in different mixture models, which include Scheffé’s quadratic model, Darroch-Waller model, log- contrast model, mixture-amount models, random coefficient models and multi-response model. Robust mixture designs and mixture designs in blocks have been also reviewed. Moreover, some applications of mixture designs in areas like agriculture, pharmaceutics and food and beverages have been presented. Familiarity with the basic concepts of design and analysis of experiments, along with the concept of optimality criteria are desirable prerequisites for a clear understanding of the book. It is likely to be helpful to both theoreticians and practitioners working in the area of mixture experiments.

Optimal Design of Experiments

Optimal Design of Experiments PDF

Author: Peter Goos

Publisher: John Wiley & Sons

Published: 2011-06-28

Total Pages: 249

ISBN-13: 1119976162

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"This is an engaging and informative book on the modern practice of experimental design. The authors' writing style is entertaining, the consulting dialogs are extremely enjoyable, and the technical material is presented brilliantly but not overwhelmingly. The book is a joy to read. Everyone who practices or teaches DOE should read this book." - Douglas C. Montgomery, Regents Professor, Department of Industrial Engineering, Arizona State University "It's been said: 'Design for the experiment, don't experiment for the design.' This book ably demonstrates this notion by showing how tailor-made, optimal designs can be effectively employed to meet a client's actual needs. It should be required reading for anyone interested in using the design of experiments in industrial settings." —Christopher J. Nachtsheim, Frank A Donaldson Chair in Operations Management, Carlson School of Management, University of Minnesota This book demonstrates the utility of the computer-aided optimal design approach using real industrial examples. These examples address questions such as the following: How can I do screening inexpensively if I have dozens of factors to investigate? What can I do if I have day-to-day variability and I can only perform 3 runs a day? How can I do RSM cost effectively if I have categorical factors? How can I design and analyze experiments when there is a factor that can only be changed a few times over the study? How can I include both ingredients in a mixture and processing factors in the same study? How can I design an experiment if there are many factor combinations that are impossible to run? How can I make sure that a time trend due to warming up of equipment does not affect the conclusions from a study? How can I take into account batch information in when designing experiments involving multiple batches? How can I add runs to a botched experiment to resolve ambiguities? While answering these questions the book also shows how to evaluate and compare designs. This allows researchers to make sensible trade-offs between the cost of experimentation and the amount of information they obtain.

Experiments with Mixtures

Experiments with Mixtures PDF

Author: John A. Cornell

Publisher: John Wiley & Sons

Published: 2011-09-20

Total Pages: 682

ISBN-13: 111815049X

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The most comprehensive, single-volume guide to conductingexperiments with mixtures "If one is involved, or heavily interested, in experiments onmixtures of ingredients, one must obtain this book. It is, as wasthe first edition, the definitive work." -Short Book Reviews (Publication of the International StatisticalInstitute) "The text contains many examples with worked solutions and with itsextensive coverage of the subject matter will prove invaluable tothose in the industrial and educational sectors whose work involvesthe design and analysis of mixture experiments." -Journal of the Royal Statistical Society "The author has done a great job in presenting the vitalinformation on experiments with mixtures in a lucid and readablestyle. . . . A very informative, interesting, and useful book on animportant statistical topic." -Zentralblatt fur Mathematik und Ihre Grenzgebiete Experiments with Mixtures shows researchers and students how todesign and set up mixture experiments, then analyze the data anddraw inferences from the results. Virtually every technique thathas appeared in the literature of mixtures can be found here, andcomputing formulas for each method are provided with completelyworked examples. Almost all of the numerical examples are takenfrom real experiments. Coverage begins with Scheffe latticedesigns, introducing the use of independent variables, and endswith the most current methods. New material includes: * Multiple response cases * Residuals and least-squares estimates * Categories of components: Mixtures of mixtures * Fixed as well as variable values for the major componentproportions * Leverage and the Hat Matrix * Fitting a slack-variable model * Estimating components of variances in a mixed model using ANOVAtable entries * Clarification of blocking mates and choice of mates * Optimizing several responses simultaneously * Biplots for multiple responses

Optimal Design of Experiments

Optimal Design of Experiments PDF

Author: Friedrich Pukelsheim

Publisher: SIAM

Published: 2006-04-01

Total Pages: 527

ISBN-13: 0898716047

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Optimal Design of Experiments offers a rare blend of linear algebra, convex analysis, and statistics. The optimal design for statistical experiments is first formulated as a concave matrix optimization problem. Using tools from convex analysis, the problem is solved generally for a wide class of optimality criteria such as D-, A-, or E-optimality. The book then offers a complementary approach that calls for the study of the symmetry properties of the design problem, exploiting such notions as matrix majorization and the Kiefer matrix ordering. The results are illustrated with optimal designs for polynomial fit models, Bayes designs, balanced incomplete block designs, exchangeable designs on the cube, rotatable designs on the sphere, and many other examples.

Experiments with Mixtures

Experiments with Mixtures PDF

Author: John A. Cornell

Publisher: Wiley-Interscience

Published: 1843

Total Pages: 428

ISBN-13:

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This guide shows how to design and set up mixture experiments, then analyze the data and draw inferences from the results. Virtually every technique that has appeared in the literature of mixtures can be found here and, for each method, computing formulas are provided with completely worked examples. Coverage begins with Scheffe lattice designs, introducing the use of independent variables and ends with the most current methods. Almost all of the numerical examples are taken from real experiments. It should serve as a supplementary text for courses on experimental design and statistical methods as well as a ready reference to important techniques for research workers in such fields as engineering, the physical sciences, agriculture and medicine.

Mathematical and Statistical Applications in Food Engineering

Mathematical and Statistical Applications in Food Engineering PDF

Author: Surajbhan Sevda

Publisher: CRC Press

Published: 2020-01-30

Total Pages: 443

ISBN-13: 0429792549

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Written by experts from all over the world, the book comprises the latest applications of mathematical and models in food engineering and fermentation. It provides the fundamentals on statistical methods to solve standard problems associated with food engineering and fermentation technology. Combining theory with a practical, hands-on approach, this book covers key aspects of food engineering. Presenting cuttingedge information, the book is an essential reference on the fundamental concepts associated with food engineering.

Optimum Experimental Designs, With SAS

Optimum Experimental Designs, With SAS PDF

Author: Anthony Atkinson

Publisher: OUP Oxford

Published: 2007-05-24

Total Pages: 528

ISBN-13: 0191537942

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Experiments on patients, processes or plants all have random error, making statistical methods essential for their efficient design and analysis. This book presents the theory and methods of optimum experimental design, making them available through the use of SAS programs. Little previous statistical knowledge is assumed. The first part of the book stresses the importance of models in the analysis of data and introduces least squares fitting and simple optimum experimental designs. The second part presents a more detailed discussion of the general theory and of a wide variety of experiments. The book stresses the use of SAS to provide hands-on solutions for the construction of designs in both standard and non-standard situations. The mathematical theory of the designs is developed in parallel with their construction in SAS, so providing motivation for the development of the subject. Many chapters cover self-contained topics drawn from science, engineering and pharmaceutical investigations, such as response surface designs, blocking of experiments, designs for mixture experiments and for nonlinear and generalized linear models. Understanding is aided by the provision of "SAS tasks" after most chapters as well as by more traditional exercises and a fully supported website. The authors are leading experts in key fields and this book is ideal for statisticians and scientists in academia, research and the process and pharmaceutical industries.

Response Surface Methodology

Response Surface Methodology PDF

Author: Raymond H. Myers

Publisher: John Wiley & Sons

Published: 2016-01-04

Total Pages: 854

ISBN-13: 1118916034

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Praise for the Third Edition: “This new third edition has been substantially rewritten and updated with new topics and material, new examples and exercises, and to more fully illustrate modern applications of RSM.” - Zentralblatt Math Featuring a substantial revision, the Fourth Edition of Response Surface Methodology: Process and Product Optimization Using Designed Experiments presents updated coverage on the underlying theory and applications of response surface methodology (RSM). Providing the assumptions and conditions necessary to successfully apply RSM in modern applications, the new edition covers classical and modern response surface designs in order to present a clear connection between the designs and analyses in RSM. With multiple revised sections with new topics and expanded coverage, Response Surface Methodology: Process and Product Optimization Using Designed Experiments, Fourth Edition includes: Many updates on topics such as optimal designs, optimization techniques, robust parameter design, methods for design evaluation, computer-generated designs, multiple response optimization, and non-normal responses Additional coverage on topics such as experiments with computer models, definitive screening designs, and data measured with error Expanded integration of examples and experiments, which present up-to-date software applications, such as JMP®, SAS, and Design-Expert®, throughout An extensive references section to help readers stay up-to-date with leading research in the field of RSM An ideal textbook for upper-undergraduate and graduate-level courses in statistics, engineering, and chemical/physical sciences, Response Surface Methodology: Process and Product Optimization Using Designed Experiments, Fourth Edition is also a useful reference for applied statisticians and engineers in disciplines such as quality, process, and chemistry.

An Agglomeration Of Experiments With Mixture Methodology Volume – I

An Agglomeration Of Experiments With Mixture Methodology Volume – I PDF

Author: Chetan Verma

Publisher: Authors' Ink Publications

Published:

Total Pages: 305

ISBN-13: 9385137999

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The book contains selected published research papers present in the literature since late fifties. The authors of the papers are eminent academicians, planners and scientists of repute in their respective areas. In the section on Introduction to Design of Experiments, the short overview is given on design of experiment, its optimality & efficiency criteria. Introduction to Mixture Problem: Design and its Construction, this section contains the basic concept and models for mixture problem, and also contains the construction of designs and its test criteria for mixture problems. Mixture experiments are generally conducted in different branches of agricultural and industrial research where it is not feasible to have the components of the mixture in full range but in some restricted space. Papers giving exhaustive reviews of such situation have been included in Constraints on the Component Proportions and Process Variable in Mixture Experiments. In the section on Optimal Mixture Design contains the papers related with optimality criteria of mixture experiments. In the section on Mixture Model Forms and Additional Topics contain the papers based on the different studies related with the mixture experiments. This is perhaps one of the few attempts to bring together papers on Mixture Experiments with emphasis on agricultural and industrial sectors for promoting mixture methodology.