Open Source Software in Life Science Research

Open Source Software in Life Science Research PDF

Author: Lee Harland

Publisher: Elsevier

Published: 2012-10-31

Total Pages: 583

ISBN-13: 1908818247

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The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems. The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an ‘omics’ platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. Discusses a broad range of applications from a variety of sectors Provides a unique perspective on work normally performed behind closed doors Highlights the criteria used to compare and assess different approaches to solving problems

Biobazaar

Biobazaar PDF

Author: Janet Hope

Publisher: Harvard University Press

Published: 2009-06-30

Total Pages: 441

ISBN-13: 0674033604

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Can the open source approach do for biotechnology what it has done for information technology? Hope's book is the first sustained and systematic inquiry into the application of open source principles to the life sciences. Traversing disciplinary boundaries, she presents a careful analysis of intellectual property-related challenges confronting the biotechnology industry and then paints a detailed picture of "open source biotechnology" as a possible solution.

Open Source Software in Life Science Research

Open Source Software in Life Science Research PDF

Author: L Harland

Publisher:

Published: 2012

Total Pages: 582

ISBN-13:

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The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems. The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an 'omics' platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. Discusses a broad range of applications from a variety of sectors Provides a unique perspective on work normally performed behind closed doors Highlights the criteria used to compare and assess different approaches to solving problems.

Practical Guide to Life Science Databases

Practical Guide to Life Science Databases PDF

Author: Imad Abugessaisa

Publisher: Springer

Published: 2022-01-07

Total Pages: 0

ISBN-13: 9789811658112

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This book provides the latest information of life science databases that center in the life science research and drive the development of the field. It introduces the fundamental principles, rationales and methodologies of creating and updating life science databases. The book brings together expertise and renowned researchers in the field of life science databases and brings their experience and tools at the fingertips of the researcher. The book takes bottom-up approach to explain the structure, content and the usability of life science database. Detailed explanation of the content, structure, query and data retrieval are discussed to provide practical use of life science database and to enable the reader to use database and provided tools in practice. The readers will learn the necessary knowledge about the untapped opportunities available in life science databases and how it could be used so as to advance basic research and applied research findings and transforming them to the benefit of human life. Chapter 2 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Open Source Software for Statistical Analysis of Big Data: Emerging Research and Opportunities

Open Source Software for Statistical Analysis of Big Data: Emerging Research and Opportunities PDF

Author: Segall, Richard S.

Publisher: IGI Global

Published: 2020-02-21

Total Pages: 237

ISBN-13: 1799827704

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With the development of computing technologies in today’s modernized world, software packages have become easily accessible. Open source software, specifically, is a popular method for solving certain issues in the field of computer science. One key challenge is analyzing big data due to the high amounts that organizations are processing. Researchers and professionals need research on the foundations of open source software programs and how they can successfully analyze statistical data. Open Source Software for Statistical Analysis of Big Data: Emerging Research and Opportunities provides emerging research exploring the theoretical and practical aspects of cost-free software possibilities for applications within data analysis and statistics with a specific focus on R and Python. Featuring coverage on a broad range of topics such as cluster analysis, time series forecasting, and machine learning, this book is ideally designed for researchers, developers, practitioners, engineers, academicians, scholars, and students who want to more fully understand in a brief and concise format the realm and technologies of open source software for big data and how it has been used to solve large-scale research problems in a multitude of disciplines.

Open-Source Lab

Open-Source Lab PDF

Author: Joshua M. Pearce

Publisher: Newnes

Published: 2013-10-04

Total Pages: 291

ISBN-13: 012410486X

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Open-Source Lab: How to Build Your Own Hardware and Reduce Scientific Research Costs details the development of the free and open-source hardware revolution. The combination of open-source 3D printing and microcontrollers running on free software enables scientists, engineers, and lab personnel in every discipline to develop powerful research tools at unprecedented low costs.After reading Open-Source Lab, you will be able to: Lower equipment costs by making your own hardware Build open-source hardware for scientific research Actively participate in a community in which scientific results are more easily replicated and cited Numerous examples of technologies and the open-source user and developer communities that support them Instructions on how to take advantage of digital design sharing Explanations of Arduinos and RepRaps for scientific use A detailed guide to open-source hardware licenses and basic principles of intellectual property

Bioinformatics Data Skills

Bioinformatics Data Skills PDF

Author: Vince Buffalo

Publisher: "O'Reilly Media, Inc."

Published: 2015-07-01

Total Pages: 613

ISBN-13: 144936750X

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Learn the data skills necessary for turning large sequencing datasets into reproducible and robust biological findings. With this practical guide, youâ??ll learn how to use freely available open source tools to extract meaning from large complex biological data sets. At no other point in human history has our ability to understand lifeâ??s complexities been so dependent on our skills to work with and analyze data. This intermediate-level book teaches the general computational and data skills you need to analyze biological data. If you have experience with a scripting language like Python, youâ??re ready to get started. Go from handling small problems with messy scripts to tackling large problems with clever methods and tools Process bioinformatics data with powerful Unix pipelines and data tools Learn how to use exploratory data analysis techniques in the R language Use efficient methods to work with genomic range data and range operations Work with common genomics data file formats like FASTA, FASTQ, SAM, and BAM Manage your bioinformatics project with the Git version control system Tackle tedious data processing tasks with with Bash scripts and Makefiles

Implementing Reproducible Research

Implementing Reproducible Research PDF

Author: Victoria Stodden

Publisher: CRC Press

Published: 2018-12-14

Total Pages: 450

ISBN-13: 131536039X

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In computational science, reproducibility requires that researchers make code and data available to others so that the data can be analyzed in a similar manner as in the original publication. Code must be available to be distributed, data must be accessible in a readable format, and a platform must be available for widely distributing the data and code. In addition, both data and code need to be licensed permissively enough so that others can reproduce the work without a substantial legal burden. Implementing Reproducible Research covers many of the elements necessary for conducting and distributing reproducible research. It explains how to accurately reproduce a scientific result. Divided into three parts, the book discusses the tools, practices, and dissemination platforms for ensuring reproducibility in computational science. It describes: Computational tools, such as Sweave, knitr, VisTrails, Sumatra, CDE, and the Declaratron system Open source practices, good programming practices, trends in open science, and the role of cloud computing in reproducible research Software and methodological platforms, including open source software packages, RunMyCode platform, and open access journals Each part presents contributions from leaders who have developed software and other products that have advanced the field. Supplementary material is available at www.ImplementingRR.org.

Python for the Life Sciences

Python for the Life Sciences PDF

Author: Alexander Lancaster

Publisher: Apress

Published: 2019-09-27

Total Pages: 396

ISBN-13: 1484245237

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Treat yourself to a lively, intuitive, and easy-to-follow introduction to computer programming in Python. The book was written specifically for biologists with little or no prior experience of writing code - with the goal of giving them not only a foundation in Python programming, but also the confidence and inspiration to start using Python in their own research. Virtually all of the examples in the book are drawn from across a wide spectrum of life science research, from simple biochemical calculations and sequence analysis, to modeling the dynamic interactions of genes and proteins in cells, or the drift of genes in an evolving population. Best of all, Python for the Life Sciences shows you how to implement all of these projects in Python, one of the most popular programming languages for scientific computing. If you are a life scientist interested in learning Python to jump-start your research, this is the book for you. What You'll Learn Write Python scripts to automate your lab calculations Search for important motifs in genome sequences Use object-oriented programming with Python Study mining interaction network data for patterns Review dynamic modeling of biochemical switches Who This Book Is For Life scientists with little or no programming experience, including undergraduate and graduate students, postdoctoral researchers in academia and industry, medical professionals, and teachers/lecturers. “A comprehensive introduction to using Python for computational biology... A lovely book with humor and perspective” -- John Novembre, Associate Professor of Human Genetics, University of Chicago and MacArthur Fellow “Fun, entertaining, witty and darn useful. A magical portal to the big data revolution” -- Sandro Santagata, Assistant Professor in Pathology, Harvard Medical School “Alex and Gordon’s enthusiasm for Python is contagious” -- Glenys Thomson Professor of Integrative Biology, University of California, Berkeley

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