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Omics Approaches, Technologies And Applications

Author: Preeti Arivaradarajan

Publisher: Springer

Published: 2019-02-04

Total Pages: 148

ISBN-13: 9811329257

This book is a concerted effort to put together the rapidly growing facets of biological data. It provides a platform for the readers to think about integrative approaches to solve complex biological problems. This fundamental book deals with the simplest concepts of omics to recent advancements in the field. The content is divided into seven chapters that provide insight into various omics approaches, omics technologies, and its applications. Each chapter delves into different molecular scales: genomics, transcriptomics, proteomics, and metabolomics. Further to provide a holistic view a chapter detailing microbiome has been included in the book. The sub-sections in the chapters is dedicated to introducing the various analytical tools such as next generation sequencing, chromatin immunoprecipitation, mass spectrometry, peptide mass fingerprinting, RNA Seq and NMR spectroscopy. It entails a chapter focused on the bioinformatics resources for analysis of the omics data. In summary, this comprehensive book emphasizes the recent advancements in the study of biomolecules spanning from DNA to metabolites.

Omics Technologies and Bio-engineering

Author: Debmalya Barh

Publisher: Academic Press

Published: 2017-12-01

Total Pages: 645

ISBN-13: 0128047496

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Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care. Covers various aspects of biotechnology and bio-engineering using omics technologies Focuses on the latest developments in the field, including biofuel technologies Provides key insights into omics approaches in personalized and precision medicine Provides a complete picture on how one can utilize omics data in molecular biology, biotechnology and human health care

OMICs Technologies

Author: Noureddine Benkeblia

Publisher: CRC Press

Published: 2012-01-24

Total Pages: 429

ISBN-13: 1439837074

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Evolution of Translational Omics

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-09-13

Total Pages: 354

ISBN-13: 0309224187

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Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Omics Technologies and Crop Improvement

Author: Noureddine Benkeblia

Publisher: CRC Press

Published: 2014-10-14

Total Pages: 396

ISBN-13: 1466586680

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Increased world population, decreased water supply, and climate change all put stresses on the global food supply. An exploration of the challenges and possible solutions to improve yields of the main crops, such as cereals, roots, tubers, and grasses, Omics Technologies and Crop Improvement reviews data on food sciences and omics. The book covers modern omic technologies such as nutrigenomics and metagenomics. It provides a detailed examination of how omics can help crop science and horticulture and introduces the benefits of using these technologies to increase crop yields and other features such as resistance and nutritional values. The book highlights crop improvements such as increased yield, drought resistance, disease resistance, and value-added performance through a non-transgenic format. It explores how the different omics technologies, especially the most recent ones (proteomics, metabolomics, nutrigenomics, ionomics, and metagenomics) would be used to improve the quantitative and qualitative features of crop plants. Topics covered include: Advances in omics for improved fresh crops Transcriptome analyses on the drought response using drought tolerant near isogenic lines Metabolite profiling that reveals different effects of nitrogen amendments on vegetables Omics technology application to forage crops improvement Secondary metabolites and plant tissue culture RNAi technology and crop improvement Gene expression analysis methods with NGS data Web database resources and crops improvement Gene Expression Networks (GEN) in crops Specific crop improvement (papaya, wheat, coffee, potato, and more) With contributions from pioneering researchers from twelve countries, the book presents a broad view of how omics would help crop science and horticulture meet the challenges of a shrinking global food supply for a burgeoning global population.

Seed Development: OMICS Technologies toward Improvement of Seed Quality and Crop Yield

Author: Ganesh K. Agrawal

Publisher: Springer

Published: 2015-01-29

Total Pages: 0

ISBN-13: 9789400799684

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The book is about the seed development in the model and crop plants. Seed development is a key step of the plant life cycle that determines the nutrient value of seeds – the life for human civilization, growth, and development. The nutrient value of seeds is mainly due to storage reserve products such as carbohydrates, lipids (triacylglycerols), and proteins. The book primarily focuses on application of the 21st century high-throughput technologies transcriptomics, proteomics, metabolomics, and systems biology in near complete understanding of the various processes involved in seed development in different crop plants. The book reveals how such technologies have revolutionized our understanding of the multilayer processes and regulations involved therein by generating large-scale datasets. Accumulated datasets provide basic knowledge to develop integrated strategies to eventually improve the nutritional value of plant seed and crop yield, a critical goal in food security issues around the globe.

Omics Technologies for Sustainable Agriculture and Global Food Security (Vol II)

Author: Anirudh Kumar

Publisher: Springer Nature

Published: 2021-08-05

Total Pages: 354

ISBN-13: 9811629560

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This edited book brings out a comprehensive collection of information on the modern omics-based research. The main focus of this book is to educate researchers about utility of omics-based technologies in rapid crop improvement. In last two decades, omics technologies have been utilized significantly in the area of plant sciences and has shown promising results. Omics technology has potential to address the challenge of food security in the near future. The comprehensive use of omics technology occurred in last two decades and helped greatly in the understanding of complex biological problems, improve crop productivity and ensure sustainable use of ecosystem services. This book is of interest to researchers and students of life sciences, biotechnology, plant biotechnology, agriculture, forestry, and environmental sciences. It is also a useful knowledge resource for national and international agricultural scientists.

Omics Approaches in Breast Cancer

Author: Debmalya Barh

Publisher: Springer

Published: 2014-10-13

Total Pages: 559

ISBN-13: 8132208439

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Breast cancer is the most common cancer in females that accounts for highest cancer specific deaths worldwide. In the last few decades research has proven that breast cancer can be treated if diagnosed at early stages and proper therapeutic strategy is adopted. Omics-based recent approaches have unveiled the molecular mechanism behind the breast tumorigenesis and aid in identification of next-generation molecular markers for early diagnosis, prognosis and even the effective targeted therapy. Significant development has taken place in the field of omics in breast cancer in the last decade. The most promising omics approaches and their outcomes in breast cancer have been presented in this book for the first time. The book covers omics technologies and budding fields such as breast cancer miRNA, lipidomics, epigenomics, proteomics, nutrigenomics, stem cell, pharmacogenomics and personalized medicine and many more along with conventional topics such as breast cancer management etc. It is a research-based reference book useful for clinician-scientists, researchers, geneticists and health care industries involved in various aspects of breast cancer. The book will also be useful for students of biomedicine, pathology and pharmacy.

Molecular Medicine

Author: Sinem Nalbantoglu

Publisher: BoD – Books on Demand

Published: 2019-11-06

Total Pages: 168

ISBN-13: 183962759X

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Molecular medicine is an applied science focused on human genes/transcripts, proteins, metabolites, and metabolic networks that describes molecular and cellular processes of health and disease onset and progression. Molecular medicine-based integrative identification and characterization of biomarker targets and their clinical translations is essential to explain/decipher the mechanism(s) underlying physiological pathways and pathological conditions, and acquire cell-targeted early interventional and therapeutic strategies in the context of precision medicine and public health. Principally, Molecular Medicine provides an overview of the latest headlines/developments of systems and molecular medicine, highlighting the emerging high-throughput technologies, promising potential applications, and progress in biomedical research and development strategies.

OMICs Technologies

Author: Noureddine Benkeblia

Publisher: CRC Press

Published: 2012-01-24

Total Pages: 433

ISBN-13: 1439837066

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Since the completion of the Human Genome Project, food and nutrition sciences have undergone a fundamental molecular transformation. New discoveries in molecular biology, analytical chemistry, and biochemistry have led to the development of new tools that are likely to revolutionize the study of food. OMICS Technologies: Tools for Food Science explores how these tools reveal the fundamental pathways and biochemical processes that drive food and nutrition sciences. In this volume, an international panel of researchers examines the rise of these new technologies—including metabolomics, metagenomics, nutrigenomics, transcriptomics, and proteomics—and describes how they translate to food science research and productive technologies. The book explains how these methods can be used to assess the quality attributes of foods and food production systems. It explores the principles that regulate food production, analyzes processing and ethical issues, and documents the transformation from industrial to sustained foods production using the OMICS tools. Providing comprehensive information on OMICS and food and nutrition science, this volume is a reliable reference for food scientists, nutritionists, and food product developers looking to implement OMIC technologies in product development. It is also a critical resource for food industry personnel, regulators, and government researchers who need to understand the role of these emerging technologies in advancing food science and nutrition.