Test No. 443: Extended One-Generation Reproductive Toxicity Study

Test No. 443: Extended One-Generation Reproductive Toxicity Study PDF

Author: OECD

Publisher: OECD Publishing

Published: 2011-07-28

Total Pages: 25

ISBN-13: 9264122559

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This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...

Test No. 421: Reproduction/Developmental Toxicity Screening Test

Test No. 421: Reproduction/Developmental Toxicity Screening Test PDF

Author: OECD

Publisher: OECD Publishing

Published: 2015-07-28

Total Pages: 14

ISBN-13: 9264242694

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This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance. It has been updated with endocrine disruptor endpoints, in particular measure of anogenital distance and male nipple retention in pups and thyroid examination.

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 240: Medaka Extended One Generation Reproduction Test (MEOGRT)

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 240: Medaka Extended One Generation Reproduction Test (MEOGRT) PDF

Author: OECD

Publisher: OECD Publishing

Published: 2023-07-04

Total Pages: 53

ISBN-13: 9264242252

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This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting chemicals (EDCs). Exposure in the MEOGRT starts with ...