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Author: OECD
Publisher: OECD Publishing
Published: 2018-06-27
Total Pages: 23
ISBN-13: 9264070788
DOWNLOAD EBOOK →This revised Test Guideline 412 (TG 412) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a limited period of time (28 days), and to provide data for quantitative inhalation risk ...
Author: OECD
Publisher: OECD Publishing
Published: 2018-06-27
Total Pages: 23
ISBN-13: 926407080X
DOWNLOAD EBOOK →This revised Test Guideline has been designed to fully characterize test article toxicity by the inhalation route for a subchronic duration (90 days), and to provide robust data for quantitative inhalation risk assessments. Groups of 10 male and 10 ...
Author: OECD
Publisher: OECD Publishing
Published: 2018-06-27
Total Pages: 20
ISBN-13: 9264284168
DOWNLOAD EBOOK →This method provides information on health hazard likely to arise from short-term exposure to a test chemical by inhalation. It is a principle of the method that only moderately toxic concentrations are used so that ‘evident toxicity’, rather than death/moribundity is used as an endpoint, and ...
Author: OECD
Publisher: OECD Publishing
Published: 2009-09-08
Total Pages: 20
ISBN-13: 9264070605
DOWNLOAD EBOOK →This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...
Author: OECD
Publisher: OECD Publishing
Published: 2008-10-16
Total Pages: 13
ISBN-13: 9264070680
DOWNLOAD EBOOK →This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...
Author: OECD
Publisher: OECD Publishing
Published: 2009-09-08
Total Pages: 27
ISBN-13: 9264076034
DOWNLOAD EBOOK →The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according to the Globally Harmonized System of ...
Author: OECD
Publisher: OECD Publishing
Published: 2018-06-27
Total Pages: 18
ISBN-13: 9264071202
DOWNLOAD EBOOK →The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...
Author: OECD
Publisher: OECD Publishing
Published: 1981-05-12
Total Pages: 9
ISBN-13: 9264070761
DOWNLOAD EBOOK →This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...
Author: OECD
Publisher: OECD Publishing
Published: 2002-02-08
Total Pages: 14
ISBN-13: 926407094X
DOWNLOAD EBOOK →A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...
Author: OECD
Publisher: OECD Publishing
Published: 1995-07-27
Total Pages: 7
ISBN-13: 9264070923
DOWNLOAD EBOOK →This Test Guideline is used in the assessment and evaluation of the toxic effects of organophosporus substances. Daily doses of the test substance are administered orally (preferably by gavage or administration of gelatin capsules) to domestic ...
