-PDF Download- Oecd Guidelines For The Testing Of Chemicals Oecd Series On Testing And Assessment Detailed Review Paper On Fish Screening Assays For The Detection Of Endocrine Active Substances EBOOK

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances

Author: OECD

Publisher: OECD Publishing

Published: 2004-11-01

Total Pages: 170

ISBN-13: 9264079157

This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances

Author: OECD

Publisher: OECD Publishing

Published: 2004-11-01

Total Pages: 171

ISBN-13: 9264079157

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OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances

Author: OECD

Publisher: OECD Publishing

Published: 2004-11-01

Total Pages: 106

ISBN-13: 9264079149

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This Detailed Review Paper (DRP) provides the current state-of-the-knowledge in the area of amphibian metamorphosis with the view to use amphibian metamorphosis as a model for the detection of chemicals affecting the thyroid axis in vertebrates.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances

Author: OECD

Publisher: OECD Publishing

Published: 2004-11-01

Total Pages: 107

ISBN-13: 9264079149

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This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of amphibian metamorphosis with the view to use amphibian metamorphosis as a model for the detection of chemicals affecting the thyroid axis in vertebrates.

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 230: 21-day Fish Assay A Short-Term Screening for Oestrogenic and Androgenic Activity, and Aromatase Inhibition

Author: OECD

Publisher: OECD Publishing

Published: 2009-09-08

Total Pages: 38

ISBN-13: 9264076220

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This Test Guideline describes an in vivo screening assay for certain endocrine active substances where sexually mature male and spawning female fish are held together and exposed to a chemical during a limited part of their life-cycle (21 days ...

OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals

Author: OECD

Publisher: OECD Publishing

Published: 2014-09-03

Total Pages: 118

ISBN-13: 9264221484

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This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.

OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition

Author: OECD

Publisher: OECD Publishing

Published: 2014-09-03

Total Pages: 156

ISBN-13: 9264221476

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This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.

OECD Series on Testing and Assessment Fish Toxicity Testing Framework

Author: OECD

Publisher: OECD Publishing

Published: 2014-09-03

Total Pages: 174

ISBN-13: 9264221433

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This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant.

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 229: Fish Short Term Reproduction Assay

Author: OECD

Publisher: OECD Publishing

Published: 2012-10-02

Total Pages: 40

ISBN-13: 9264185267

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This Test Guideline describes an in vivo screening assay for fish reproduction where sexually mature male and spawning female fish are held together and exposed to a chemical during a limited part of their life-cycle (21 days). The short term ...

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 250: EASZY assay - Detection of Endocrine Active Substances, acting through estrogen receptors, using transgenic tg(cyp19a1b:GFP) Zebrafish embrYos

Author: OECD

Publisher: OECD Publishing

Published: 2021-06-17

Total Pages: 45

ISBN-13: 9264886109

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The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b promoter. The EASZY assay allows for the detection of estrogenic activity of chemicals on transgenic tg(cyp19a1b:GFP) Zebrafish embryos exposed for 96 hours during the embryonic stages of development.