Immunology, Inflammation and Diseases of the Eye

Immunology, Inflammation and Diseases of the Eye PDF

Author: Darlene A. Dartt

Publisher: Academic Press

Published: 2011-05-05

Total Pages: 452

ISBN-13: 0123819741

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This selection of articles from the Encyclopedia of the Eye provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more. The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of ocular immunology Chapters are carefully selected from the Encyclopedia of the Eye by the world's leading vision researchers The best researchers in the field provide their conclusions in the context of the latest experimental results

Ocular Immunology in Health and Disease

Ocular Immunology in Health and Disease PDF

Author: Steven B. Koevary

Publisher:

Published: 1999

Total Pages: 212

ISBN-13:

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Provides detailed information about ocular immunity and the basis of ocular immune privilege, and elaborates on the role of immune effector mechanisms in specific ocular conditions. Offers a detailed overview of immune system function, discusses autoimmune diseases and allergic conditions affecting the eye and their treatment, reviews the immunology of corneal graft rejection, and discusses the immune system's role in ocular tumor elimination and corneal transplant. Annotation copyrighted by Book News, Inc., Portland, OR

Immuno-ophthalmology

Immuno-ophthalmology PDF

Author: Uwe Pleyer

Publisher: Karger Medical and Scientific Publishers

Published: 1999-01-01

Total Pages: 260

ISBN-13: 3805568630

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Although considerable light has been shed on the mechanisms of ocular immunity over the past 20 years, a complete understanding still eludes our grasp. To many ophthalmologists immunology itself is a comparatively new field. This volume will bring the latest findings in immunological research and the resulting new therapy methods to the ophthalmologist in practice. The scope of the topics goes from general principles of immuno-ophthalmology to more specific ones such as immunology of corneal transplantation or immune regulation of uveoretinal inflammation. With its broad scope of contributions, this publication will not only be significant to the ophthalmologist, but also to pediatricians, specialists in internal medicine as well as dermatologists confronted with eye diseases.

Advances in Ocular Immunology

Advances in Ocular Immunology PDF

Author: Robert B. Nussenblatt

Publisher: Elsevier Science & Technology

Published: 1994

Total Pages: 504

ISBN-13:

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This text examines the status of ocular immunology, with a mixture of clinical and basic research information. It should be clear to the reader that ocular immunology's various models for organ specific immune responses are adept at yielding information useful to all in immunology.

Immunology of Eye Diseases

Immunology of Eye Diseases PDF

Author: S. Lightman

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 178

ISBN-13: 9400924909

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The eye can become involved in immune-mediated diseases that affect it alone or as part of a multi-organ disease process. Much immunological attention has been focused on other organs affected by these processes and the subject of the immunology of eye diseases is a relatively new one. Many of these diseases that involve the eye are not life-threatening but can result in devastat ing loss of sight that if bilateral, will have major effects on the patient's life. Systemic immunological investigations are generally unhelpful in these patients and one of the major problems in this field has been the lack of diseased tissue available for examination to determine the pathological processes involved. Our poor understanding of basic mechanisms of disease in the eye has meant that treatment of many of these conditions is often inadequate. It has become possible to apply in the eye many ofthe techniques used to investigate the role of the immune system in other systems. Animal models of many of the disease processes have also allowed dissection of the immune response both within and outside the eye. It is my belief that a greater understanding of the mechanisms by which the structures in the eye become damaged will allow more specific and effective therapeutic strategies to be devised.

Handbook of Ocular Immunology

Handbook of Ocular Immunology PDF

Author: R.J.W de Keizer

Publisher: CRC Press

Published: 1998-01-01

Total Pages: 240

ISBN-13: 9789070430368

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A comprehensive and authoritative survey of ocular immunology written by 21 international specialists. It contains the revised and extended lectures given at the Boerhave Course, 1995, at the University of Leyden, The Netherlands.

Immunology of Ocular Tumors

Immunology of Ocular Tumors PDF

Author: M. Jager

Publisher: CRC Press

Published: 2002-01-01

Total Pages: 284

ISBN-13: 9789026519314

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The eye and the ocular adnexa may give rise to over three hundred histologically different tumors - by far the largest tumor variety of the human body. However, the immunological behavior of these tumors has only been explored in some cases, although it is well established that the eye is an immune-privileged site in which cells that express foreign antigens escape immune-mediated elimination. Human tumors also create an immune-privileged surrounding and thereby escape from anti-tumor immune responses. Highlighting aspects of ocular and general tumor, this text summarizes the role of the immune system and how tumor tissue can influence various parameters (T-cells, NK-cells, HLA-expression, apoptosis), leading to escape mechanisms used by the tumor. New therapeutic regimens urgently required by patients are also reviewed, and the immunological behavior of skin melanoma is compared to choroidal melanoma, whilst basal cell carcinoma of the ocular lid is compared to those of the skin.

Immune Response and the Eye

Immune Response and the Eye PDF

Author: Jerry Y. Niederkorn

Publisher: Karger Medical and Scientific Publishers

Published: 2007-01-01

Total Pages: 357

ISBN-13: 3805581874

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In memory of J. Wayne Streilein, the pioneer in ocular immunology The second edition of Immune Response and the Eye' highlights recent insights into the dangerous compromise' between the immune system and the eye, which protects the eye against pathogens while limiting inflammation and immune-mediated injury to ocular tissues with little or no regenerative potential. It discusses the broad spectrum of physiological, immunological, anatomical, and biochemical adaptations that conspire to closely regulate the tone and tenor of immune responses in the eye. This volume further describes immune-mediated diseases that occur when the compromise between the immune system and the eye is breached. This breakdown in immune privilege threatens the vision of millions each year. Finally, recent advances in ocular immunology are presented, which offer potential therapeutic applications in corneal and retinal transplantation and in the management of blinding autoimmune diseases of the eye. Eye researchers, ophthalmologists and immunologists will appreciate the state-of-the-art and authoritative information presented in Immune Response and the Eye'