Novel Approaches for Single Molecule Activation and Detection

Novel Approaches for Single Molecule Activation and Detection PDF

Author: Fabio Benfenati

Publisher: Springer

Published: 2014-06-26

Total Pages: 227

ISBN-13: 3662433672

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How can we obtain tools able to process and exchange information at the molecular scale? In order to do this, it is necessary to activate and detect single molecules under controlled conditions. This book focuses on the generation of biologically-inspired molecular devices. These devices are based on the developments of new photonic tools able to activate and stimulate single molecule machines. Additionally, new light sensitive molecules can be selectively activated by photonic tools. These technological innovations will provide a way to control activation of single light-sensitive molecules, allowing the investigation of molecular computation in a biological environment.

New Techniques in Systems Neuroscience

New Techniques in Systems Neuroscience PDF

Author: Adam D. Douglass

Publisher: Springer

Published: 2015-04-13

Total Pages: 309

ISBN-13: 3319129139

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This volume is essential reading for anyone wishing to understand the recent explosion of experimental tools in neuroscience that now make it possible to manipulate, record, and understand neuronal activity within the intact brain, and which are helping us learn how the many neurons that comprise a network act together to control behavior. Leaders in the field discuss the latest developments in optogenetics, functional imaging, circuit mapping, and the application of these tools to complex biological problems.

All-Optical Methods to Study Neuronal Function

All-Optical Methods to Study Neuronal Function PDF

Author: Eirini Papagiakoumou

Publisher: Springer Nature

Published: 2023-02-20

Total Pages: 424

ISBN-13: 1071627643

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This open access volume provides an overview of the latest methods used to study neuronal function with all-optical experimental approaches, where light is used for both stimulation and monitoring of neuronal activity. The chapters in this book cover topics over a broad range, from fundamental background information in both physiology and optics in the context of all-optical neurophysiology experiments, to the design principles and hardware implementation of optical methods used for photoactivation and imaging. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, All-Optical Methods to Study Neuronal Function is a valuable resource for researchers in various disciplines such as physics, engineering, and neuroscience. This book will serve as a guide to establish useful references for groups starting out in this field, and provide insight on the optical systems, actuators, and sensors. This is an open access book.

Super-Resolution Imaging in Biomedicine

Super-Resolution Imaging in Biomedicine PDF

Author: Alberto Diaspro

Publisher: CRC Press

Published: 2016-11-03

Total Pages: 448

ISBN-13: 1482244357

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This book encompasses the full breadth of the super-resolution imaging field, representing modern techniques that exceed the traditional diffraction limit, thereby opening up new applications in biomedicine. It shows readers how to use the new tools to increase resolution in sub-nanometer-scale images of living cells and tissue, which leads to new information about molecules, pathways and dynamics. The book highlights the advantages and disadvantages of the techniques, and gives state-of-the-art examples of applications using microscopes currently available on the market. It covers key techniques such as stimulated emission depletion (STED), structured illumination microscopy (SSIM), photoactivated localization microscopy (PALM), and stochastic optical reconstruction microscopy (STORM). It will be a useful reference for biomedical researchers who want to work with super-resolution imaging, learn the proper technique for their application, and simultaneously obtain a solid footing in other techniques.

Quick Reference NeuroScience for Rehabilitation Professionals

Quick Reference NeuroScience for Rehabilitation Professionals PDF

Author: Sharon A. Gutman

Publisher: Taylor & Francis

Published: 2024-06-01

Total Pages: 771

ISBN-13: 1040137415

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"Quick Reference NeuroScience for Rehabilitation Professionals: The Essential Neurologic Principles Underlying Rehabilitation Practice, Third Edition" is a user-friendly, comprehensive text that specifically addresses the key information needed to understand the neuroscience of clinical rehabilitation. A concise and quick reference for the practitioner and student who are learning or reviewing the most relevant neuroscience principles supporting rehabilitation therapy. The updated third edition continues to meet a need in the rehabilitation profession that has gone unfilled - the ability to break down neuroscience information into the essential principles that can be used to understand neurological conditions and the principles underlying rehabilitation evaluation and practice. This fully-updated third edition provides a quick review of specific neuroscience concepts and principles that support rehabilitation interventions. In this era of information overload, this text rapidly and thoroughly provides condensed information in a user-friendly, easy-to-use format for readers to review and convey relevant information to patients. Sharon Gutman has organised the text into three parts: the first addresses neuroanatomy; the second addresses the function of neurological systems underlying physical, psychiatric, cognitive, and visual perceptual disorders; and the final section addresses clinical neuropathology related to ageing, addiction, memory, and the neurological substrates of sex and gender. A specific section describes the common neurodiagnostic tests that therapists do not administer but must have knowledge of when results are discussed at treatment team meetings. Features of the third edition: Presented in a simple and organised bulleted format. Large-scale colour illustrations to easily visualise neuroanatomical structures and systems. Text boxes to apply key neuroscience concepts to the understanding of common neurological disorders and treatment. Updated clinical test questions and glossary. The third edition bridges a gap by quickly providing the rehabilitation professional with the most salient information needed to understand neurologic principles underlying rehabilitation practice.

Single Molecule Analysis

Single Molecule Analysis PDF

Author: Iddo Heller

Publisher: Humana

Published: 2023-11-09

Total Pages: 0

ISBN-13: 9781071633762

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This third edition volume expands on the previous editions with new discussions on the latest techniques and developments in the field. The chapters in this book are organized into four parts, and cover topics such as optical tweezers; single-molecule fluorescence tools; atomic force microscopy; magnetic tweezers; applications to virus protein shells, unfolding of proteins, nucleic acids, motor proteins, in vivo and in vitro; and protocols to establish specific surface interactions and perform force calibration. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Single Molecule Analysis: Methods and Protocols, Third Edition is a valuable resource for all researchers who want to learn more about this exciting and still expanding field. Chapters 2, 7, 8, 9, 12, 18, and 19 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

An Introduction to Single Molecule Biophysics

An Introduction to Single Molecule Biophysics PDF

Author: Yuri L. Lyubchenko

Publisher:

Published: 2018-06-28

Total Pages: 0

ISBN-13: 9781138615960

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This introductory book broadly covers the foundations, principles, and methodologies of single molecule fluorescence and force probe techniques as applied to the most important and timely biological problems, providing a first introduction to key concepts and highlights the advantages and pitfalls of each of these exciting emerging methods.

Gangliosides in Health and Disease

Gangliosides in Health and Disease PDF

Author:

Publisher: Academic Press

Published: 2018-04-25

Total Pages: 480

ISBN-13: 0128123427

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Gangliosides in Health and Disease, Volume 156, presents the latest information on Gangliosides, a class of glycolipids that are found on all vertebrate cell surfaces, and are particularly abundant in the brain. Individual chapters in this new volume cover Gangliosides as Toxin Receptors, Gangliosides in Cancer Cell Signaling, Gangliosides in inflammation and neurodegeneration, Gangliosides as functional galectin receptors, Gangliosides in signal transduction, Gangliosides in brain tumor immunology, and Gangliosides in axon regeneration and stability, amongst other related topics. This book brings together world experts in ganglioside structure and function who have been assembled to contribute to this thorough update of the field. Contains accessible content that is ideal for students and researchers alike Written by leading authorities in the field

Advances in Molecular Nanotechnology Research and Application: 2013 Edition

Advances in Molecular Nanotechnology Research and Application: 2013 Edition PDF

Author:

Publisher: ScholarlyEditions

Published: 2013-06-21

Total Pages: 903

ISBN-13: 1481683284

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Advances in Molecular Nanotechnology Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Molecular Motors. The editors have built Advances in Molecular Nanotechnology Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Molecular Motors in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Molecular Nanotechnology Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

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