New Principles in Developmental Processes

New Principles in Developmental Processes PDF

Author: Hisato Kondoh

Publisher: Springer

Published: 2014-07-08

Total Pages: 316

ISBN-13: 4431546340

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During the last decade, modern technologies have made a revolutionary change in developmental biology. The molecular and cellular processes in live embryos can now be visualized thanks to technologies using fluorescent proteins. The whole genome information of a wide range of animal species has now become available, confirming the common principles that operate in every species. These and other advances in our understanding of the developmental processes during embryogenesis and tissue regeneration have put forward new principles. Those new principles will also be important in the stem cell biology, branched from developmental biology, in order to generate a particular tissue by manipulating stem cells. This book is planned to introduce these new principles to readers who are working in developmental biology and/or stem cell biology fields, with an emphasis on genetic and cellular processes.

Principles of Developmental Genetics

Principles of Developmental Genetics PDF

Author: Sally A. Moody

Publisher: Elsevier

Published: 2007-07-19

Total Pages: 1080

ISBN-13: 0080550711

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Unlike anything currently available in the market, Dr. Sally A. Moody and a team of world-renowned experts provide a groundbreaking view of developmental genetics that will influence scientific approaches in embryology, comparative biology, as well as the newly emerging fields of stem cell biology and regenerative medicine. Principles of Developmental Genetics highlights the intersection of developmental biology with new revolutionary genomic technologies, and details how these advances have accelerated our understanding of the molecular genetic processes that regulates development. This definitive resource provides researchers with the opportunity to gain important insights into the clinical applicability of emerging new technologies and animal model data. This book is a must-have for all researchers in genetics, developmental biology, regenerative medicine, and stem cell biology. • Includes new research not previously published in any other book on the molecular genetic processes that regulates development • Chapters present a broad understanding on the application of animal model systems, allowing researchers to better treat clinical disorders and comprehend human development • Relates the application of new technologies to the manipulation of stem cells, causes of human birth defects, and several human disease conditions • Each chapter includes a bulleted summary highlighting clinical aspects of animal models

Lean Product and Process Development, 2nd Edition

Lean Product and Process Development, 2nd Edition PDF

Author: Allen C. Ward

Publisher: Lean Enterprise Institute

Published: 2014-03-05

Total Pages: 509

ISBN-13: 1934109444

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"The P-51 Mustang—perhaps the finest piston engine fighter ever built—was designed and put into flight in just a few months. Specifications were finalized on March 15, 1940; the airfoil prototype was complete on September 9; and the aircraft made its maiden flight on October 26. Now that is a lean development process!" —Allen Ward and Durward Sobek, commenting on the development of the P-51 Mustang and its exemplary use of trade-off curves. Shingo Research and Professional Publication Award recipient, 2008 Despite attempts to interpret and apply lean product development techniques, companies still struggle with design quality problems, long lead times, and high development costs. To be successful, lean product development must go beyond techniques, technologies, conventional concurrent engineering methods, standardized engineering work, and heavyweight project managers. Allen Ward showed the way. In a truly groundbreaking first edition of Lean Product and Process Development, Ward delivered -- with passion and penetrating insights that cannot be found elsewhere -- a comprehensive view of lean principles for developing and sustaining product and process development. In the second edition, Durward Sobek, professor of Mechanical and Industrial Engineering at Montana State University—and one of Ward’s premier students—edits and reorganizes the original text to make it more accessible and actionable. This new edition builds on the first one by: Adding five in-depth and inspiring case studies. Including insightful new examples and illustrations. Updating concepts and tools based on recent developments in product development. Expanding the discussion around the critical concept of set-based concurrent engineering. Adding a more detailed table of contents and an index to make the book more accessible and user-friendly. The True Purpose of Product Development Ward’s core thesis is that the very aim of the product development process is to create profitable operational value streams, and that the key to doing so predictably, efficiently, and effectively is to create useable knowledge. Creating useable knowledge requires learning, so Ward also creates a basic learning model for development. But Ward not only describes the technical tools needed to make lean product and process development actually work. He also delineates the management system, management behaviors, and mental models needed. In this breakthrough text, Ward: Asks fundamental questions about the purpose and “value added” in product development so you gain a crystal clear understanding of essential issues. Shows you how to find the most common forms of “knowledge waste” that plagues product development. Identifies four “cornerstones” of lean product development gleaned from the practices of successful companies like Toyota and its partners, and explains how they differ from conventional practices. Gives you specific, practical recommendations for establishing your own lean development processes. Melds observations of effective teamwork from his military background, engineering fundamentals from his education and personal experience, design methodology from his research, and theories about management and learning from his study of history and experiences with customers. Changes your thinking forever about product development.

Transforming the Workforce for Children Birth Through Age 8

Transforming the Workforce for Children Birth Through Age 8 PDF

Author: National Research Council

Publisher: National Academies Press

Published: 2015-07-23

Total Pages: 587

ISBN-13: 0309324882

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Children are already learning at birth, and they develop and learn at a rapid pace in their early years. This provides a critical foundation for lifelong progress, and the adults who provide for the care and the education of young children bear a great responsibility for their health, development, and learning. Despite the fact that they share the same objective - to nurture young children and secure their future success - the various practitioners who contribute to the care and the education of children from birth through age 8 are not acknowledged as a workforce unified by the common knowledge and competencies needed to do their jobs well. Transforming the Workforce for Children Birth Through Age 8 explores the science of child development, particularly looking at implications for the professionals who work with children. This report examines the current capacities and practices of the workforce, the settings in which they work, the policies and infrastructure that set qualifications and provide professional learning, and the government agencies and other funders who support and oversee these systems. This book then makes recommendations to improve the quality of professional practice and the practice environment for care and education professionals. These detailed recommendations create a blueprint for action that builds on a unifying foundation of child development and early learning, shared knowledge and competencies for care and education professionals, and principles for effective professional learning. Young children thrive and learn best when they have secure, positive relationships with adults who are knowledgeable about how to support their development and learning and are responsive to their individual progress. Transforming the Workforce for Children Birth Through Age 8 offers guidance on system changes to improve the quality of professional practice, specific actions to improve professional learning systems and workforce development, and research to continue to build the knowledge base in ways that will directly advance and inform future actions. The recommendations of this book provide an opportunity to improve the quality of the care and the education that children receive, and ultimately improve outcomes for children.

Frugal Innovation and the New Product Development Process

Frugal Innovation and the New Product Development Process PDF

Author: Stephanie B.M. Cadeddu

Publisher: Routledge

Published: 2019-01-17

Total Pages: 222

ISBN-13: 0429671180

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This book explores the new product development process of firms developing frugal innovation for the base-of-the-pyramid (BOP) markets in developing countries. Frugal innovations are products characterised by an affordable price-point, durability, usability and core functionalities that are highly adapted to BOP consumers’ needs. Frugal products have the potential to drive the development progress and living standards of low-income consumers. With an innovation framework developed from worldwide frugal case studies, this book provides detailed insights through two in-depth start-up firms in Indonesia that have successfully launched frugal products for the low-income market. These two start-ups have addressed two major development challenges for not just Indonesia, but also the global BOP market – traditional methods of cooking and access to clean drinking water. A detailed roadmap is developed from insights into the processes and management decisions of these two start-ups and combined with previous studies on frugal products. Providing a detailed roadmap across the different phases and stages of the new product development process when developing frugal products, this book will be insightful to not only innovators but also investors and government agencies supporting their activities.

Human-System Integration in the System Development Process

Human-System Integration in the System Development Process PDF

Author: National Research Council

Publisher: National Academies Press

Published: 2007-06-15

Total Pages: 397

ISBN-13: 0309106575

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In April 1991 BusinessWeek ran a cover story entitled, "I Can't Work This ?#!!@ Thing," about the difficulties many people have with consumer products, such as cell phones and VCRs. More than 15 years later, the situation is much the same-but at a very different level of scale. The disconnect between people and technology has had society-wide consequences in the large-scale system accidents from major human error, such as those at Three Mile Island and in Chernobyl. To prevent both the individually annoying and nationally significant consequences, human capabilities and needs must be considered early and throughout system design and development. One challenge for such consideration has been providing the background and data needed for the seamless integration of humans into the design process from various perspectives: human factors engineering, manpower, personnel, training, safety and health, and, in the military, habitability and survivability. This collection of development activities has come to be called human-system integration (HSI). Human-System Integration in the System Development Process reviews in detail more than 20 categories of HSI methods to provide invaluable guidance and information for system designers and developers.

Organization Development

Organization Development PDF

Author: Gary McLean

Publisher: Berrett-Koehler Publishers

Published: 2005-12-02

Total Pages: 481

ISBN-13: 1605093343

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Designed for use in undergraduate and graduate programs in organization development, management, human resource development, and industrial and organizational psychology, Organization Development provides readers with an overview of the field and acquaints them with the basic principles, practices, values, and skills of OD. Covering every aspect of the work of an OD professional and featuring numerous illustrative case studies, it shows how OD professionals actually get work and what the first steps in any OD effort should be. Author Gary McLean surveys different ways to assess an organizational situation—including a comparison of the Action Research and Appreciative Inquiry models—and provides forms for devising an action plan based on that assessment. He then looks at how to choose and implement a range of interventions at different levels, as well as how to evaluate the results of an intervention. Organization Development goes beyond the organizational level to look at the application of OD on community, national, regional, and global levels. And it successfully combines theory and practice; process and outcomes; performance and affective results; effectiveness and efficiency.

Applications of Nonlinear Dynamics To Developmental Process Modeling

Applications of Nonlinear Dynamics To Developmental Process Modeling PDF

Author: Karl M. Newell

Publisher: Psychology Press

Published: 2014-03-05

Total Pages: 330

ISBN-13: 1317779126

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There has been an increasing interest in the application of dynamical systems to the study of development over the last decade. The explosion of the dynamical systems framework in the physical and biological sciences has opened the door to a new Zeitgeist for studying development. This appeal to dynamical systems by developmentalists is natural given the intuitive links between the established fundamental problems of development and the conceptual and operational scope of nonlinear dynamical systems. This promise of a new approach and framework within which to study development has led to some progress in recent years but also a growing appreciation of the difficulty of both fully examining the new metaphor and realizing its potential. Divided into 4 parts, this book is a result of a recent conference on dynamical systems and development held at Pennsylvania State University. The first 3 parts focus on the content domains of development that have given most theoretical and empirical attention to the potential applications of dynamical systems--physical growth and movement, cognition, and communication. These parts show that a range of nonlinear models have been applied to a host of developmental phenomena. Part 4 highlights two particular methodological issues that hold important implications for the modeling of developmental phenomena with dynamical systems techniques.

Urban Design in the Real Estate Development Process

Urban Design in the Real Estate Development Process PDF

Author: Steve Tiesdell

Publisher: John Wiley & Sons

Published: 2011-04-08

Total Pages: 279

ISBN-13: 1444341162

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Urban design enables better places to be created for people and is thus seen in Urban Design in the Real Estate Development Process as a place-making activity, rather than the application of architectural aesthetics. Urban design policy can change the 'decision environment' of developers, financiers, designers and other actors in the real estate development process to make them take place-making more seriously. This book reports diverse international experience from Europe and North America on the role and significance of urban design in the real estate development process and explores how higher quality development and better places can be achieved through public policy. The book is focused on four types of policy tool or instrument that have been deployed to promote better urban design: those that seek to shape, regulate or provide stimulus to real estate markets along with those aim to build capacity to achieve these. Urban design is therefore seen as a form of public policy that seeks to steer real estate development towards policy-shaped rather than market-led outcomes. The editors set the examples, case studies and evidence from international contributors within a substantive discussion of the impact of urban design policy tools and actions in specific development contexts. Contributions from leading urban design theorists and practitioners explore how: Masterplanning and infrastructure provision encourage high quality design Design codes reconcile developers' needs for certainty and flexibility Clear policy combined with firm regulation can transform developer behaviour Intelligent parcelisation can craft the character of successful new urban districts Powerful real estates interests can capture regulatory initiatives Stimulus instruments can encourage good design Development competitions need careful management Design review can foster developer commitment to design excellence Speculative housebuilders respond in varied ways to the brownfield design challenge Physical-financial models could help in assessing the benefits of design investment Urban design can add value to the benefit of developers and cities as a whole.

The Design and Development Process

The Design and Development Process PDF

Author: David C. Wynn

Publisher: Springer Nature

Published: 2023-11-14

Total Pages: 365

ISBN-13: 3031381688

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This book explores a process perspective on design and development, grounded in research in design studies, engineering design and systems design. The design and development process is important---it creates all artificial products and systems and determines how well they address human needs. The process perspective set out in this book has value for design and development practice and education, and is in its own right a fascinating topic of investigation. This book expands on the foundations of a process perspective and discusses its realisation in many process models, theories and approaches that have been developed over the years. The chapters provide connected overviews of key concepts and introduce new conceptual frameworks to clarify relationships between the contributions discussed. Practical considerations and competencies required to realise the tangible benefits of a process perspective are also discussed. A unique aspect of this book is that it brings together many perspectives on the design and development process: those that focus on individual design activity through to those that focus on large-scale development projects; those of research interest and those of practical interest; and those of relevance to design contexts ranging from human-centered design to engineering design and systems design. The chapter bibliographies collect carefully-selected recommendations for further reading on each topic discussed. The book additionally contains many figures presented in colour, visually reflecting each topic's relationship to the new organising frameworks that are introduced.