Neuroglia in the Aging Brain
Author: Jean de Vellis
Publisher: Springer Science & Business Media
Published: 2001-11-06
Total Pages: 513
ISBN-13: 1592591051
DOWNLOAD EBOOK →A distinguished panel of internationally recognized neuroscientists comprehensively review the involvement of and changes in glial cells both during the normal aging process and in the major disorders of old age. Topics range from the cellular and molecular changes that occur with aging-especially aging-associated activation of astrocytes and microglia and its relation to neuronal injury and repair-to neuron-glia intercommunication. The contributors show how glial signals may be modulated by hormones, growth factors, neurotransmitters, intracellular metabolism, and intercellular exchanges, as well as by aging of the blood-brain barrier.