Neuroendocrine Molecular Biology
Author: G. Fink
Publisher:
Published: 2014-09-01
Total Pages: 516
ISBN-13: 9781468451320
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Neuroendocrine Molecular Biology
Author: G. Fink
Publisher: Springer Science & Business Media
Published: 2013-03-09
Total Pages: 488
ISBN-13: 1468451316
DOWNLOAD EBOOK →The 13th Annual Meeting of the Foundation was held in Edinburgh during September 1985. The subject was neuroendocrine molecular biology which brought together leading scientists in the fields of molecular genetics, neuroendocrinology and developmental neuro biology. The conference was most stimulating and as the Proceedings show, novel data presented was of the highest quality. The topics presented were grouped under the headings;, "Molecular Biology of the Nervous System", ''IlIRH - New Perspectives', ''Neuropeptides'', "Oxytocin and Vasopressin", "Transcriptional and Post-Translational Regulation of Neuropeptide Synthesis", "Neuroendocrine Mechanisms at the Cellular Level", "Receptors - Cellular and Molecular Biology" and "Clinical Applications". The
Neuroendocrine Tumours
Author: Suayib Yalcin
Publisher: Springer
Published: 2015-05-27
Total Pages: 569
ISBN-13: 3662452154
DOWNLOAD EBOOK →This book is a timely textbook that covers all aspects of neuroendocrine tumors (NET) from epidemiology, pathological classification and evaluation and molecular biology through to diagnostic imaging methods and therapeutic options, including the latest targeted therapies. The various types of NET are individually discussed, including carcinoid tumors, insulinomas, gastrinomas, glucagonomas, VIPomas, somatostatinomas, PPomas, medullary thyroid carcinomas, adrenocortical cancer, pheochromocytomas, paragangliomas and non-functioning pancreatic NETs. The contributing authors are internationally recognized experts who bring a wealth of experience to the subject. This book will be an invaluable source of information for practicing medical oncologists, surgeons, endocrinologists, gastroenterologists and pathologists and also trainees.
Neuroendocrine Molecular Biology
Author: G. Fink
Publisher: Springer
Published: 2012-06-14
Total Pages: 498
ISBN-13: 9781468451337
DOWNLOAD EBOOK →The 13th Annual Meeting of the Foundation was held in Edinburgh during September 1985. The subject was neuroendocrine molecular biology which brought together leading scientists in the fields of molecular genetics, neuroendocrinology and developmental neuro biology. The conference was most stimulating and as the Proceedings show, novel data presented was of the highest quality. The topics presented were grouped under the headings;, "Molecular Biology of the Nervous System", ''IlIRH - New Perspectives', ''Neuropeptides'', "Oxytocin and Vasopressin", "Transcriptional and Post-Translational Regulation of Neuropeptide Synthesis", "Neuroendocrine Mechanisms at the Cellular Level", "Receptors - Cellular and Molecular Biology" and "Clinical Applications". The
Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances
Author: Aejaz Nasir
Publisher: Springer
Published: 2016-08-31
Total Pages: 536
ISBN-13: 1493934260
DOWNLOAD EBOOK →This comprehensive subspecialty reference book on NeuroEndocrine Tumor (NET) pathology brings together the diagnostic and clinical expertise of an outstanding team of practicing neuroendocrine pathologists and oncologists. In addition to in-depth coverage of clinico-pathologic aspects of NETs of the various organ systems, the recent histological grading and staging schemes proposed by the North American and European NeuroEndocrine Tumor Societies (NANETS, ENETS), the World Health Organization (WHO) and the American Joint Committee on Cancer (AJCC), this book also focuses on the recent molecular and therapeutic advances in the field of NET pathology and oncology. Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances will be an essential reference book for anatomic pathology (histopathology) residents, fellows, surgical pathologists, researchers, oncologists, surgeons and other medical professionals practicing advanced NET Pathology and Oncology in academia, community, private practice and research settings.
Neuroendocrine Tumors
Author: James C. Yao
Publisher: Springer Science & Business Media
Published: 2011-07-12
Total Pages: 274
ISBN-13: 1603279970
DOWNLOAD EBOOK →New research has shown that neuroendocrine tumors are more common than previously thought. Progress in our understanding of the molecular pathogenesis of these not-so-rare cancers has resulted in renewed interest in developing innovative therapeutic options. In particular, novel molecular targeted agents have been shown to have significant anti-tumor activity, and integration of these therapies has led to critical advances in management. In this volume, an outstanding group of the world’s leaders in the field have assembled to convey their knowledge of the epidemiology, biology, and management of all the major types of neuroendocrine tumors. The book takes a multi-modality approach to understanding disease processes and therapeutics, including chapters on medical and surgical treatment as well as a chapter devoted to imaging. Throughout, the authors emphasize recent advances in our understanding of molecular biology and the subsequent emerging therapeutic options.
Molecular Neuroendocrinology
Author: David Murphy
Publisher: John Wiley & Sons
Published: 2016-03-07
Total Pages: 481
ISBN-13: 1118760379
DOWNLOAD EBOOK →Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. The 19 chapters are divided into four sectors: A) describes and explores the genome, its evolution, expression and the mechanisms that contribute to protein, and hence biological, diversity. B) discusses the mechanisms that enhance peptide and protein diversity beyond what is encoded in the genome through post-translational modification. C) considers the molecular tools that today’s neuroendocrinologists can use to study the regulation and function of neuroendocrine genes within the context of the intact organism. D) presents a range of case studies that exemplify the state-of-the-art application of genomic technologies in physiological and behavioural experiments that seek to better understand complex biological processes. • Written by a team of internationally renowned researchers • Both print and enhanced e-book versions are available • Illustrated in full colour throughout This is the third volume in a new Series ‘Masterclass in Neuroendocrinology’ , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA
Neuroendocrinology
Author: David A. Lovejoy
Publisher: John Wiley & Sons
Published: 2005-11-01
Total Pages: 416
ISBN-13: 0470015683
DOWNLOAD EBOOK →There has been an explosion of interest in the field of neuroendocrinology over the last twenty years with the discovery of neurohormones regulating virtually everything from growth and development to sexual and aggressive behavior. This book provides a much-needed introduction to neuroendocrinology from a zoological and evolutionary perspective. It covers the evolution, development and description of the neuroendocrine system throughout the animal kingdom. Specific topics covered include: The Evolution of early neuroendocrine systems in primitive animals Structural characterisation, molecular biology and biochemistry of neuroendocrine agents A profiles section on unusual aspects of neuroendocrine physiology written by leaders in the field A unique section on the actions of environmental chemicals effect neuroendocrine systems in various species
Neuroendocrine Neoplasia Management
Author: Giordano Beretta
Publisher: Springer Nature
Published: 2021-07-16
Total Pages: 331
ISBN-13: 3030728307
DOWNLOAD EBOOK →This book provides the most recent update on the management of neuroendocrine neoplasia (NEN), a term covering all tumors of various organs and/or with a particular histology, including MEN (multiple endocrine neoplasia) related tumors, MiNEN (mixed neuroendocrine-non-neuroendocrine neoplasms), NEC (neuroendocrine carcinoma) and Merkel’s carcinoma. NENs are heterogeneous in their biology, clinical presentation and prognosis, showing a great variability in aggressiveness and therapy response. As a result, their treatment is based on a large spectrum of options. The standard therapies are surgery in early disease, various loco-regional procedures in certain conditions and mostly of a palliative nature in metastatic disease. At present, thanks to our increased understanding of molecular signaling pathways, several pharmacological approaches can be used in patients with advanced NENs. Somatostatin analogs display both anti-tumor effects and symptom control. Novel peptide-radio-receptor treatment (PRRT) is used in patients with well differentiated tumors. The agents targeting angiogenesis and/or PI3K/AKT/mTOR pathway, alone or in combination with analogues, have provided encouraging results in advanced disease. The first part of the book focuses on the history, epidemiology and the most relevant scientific achievements, covering the discoveries in genetic and molecular biology, the endoscopic techniques with guided biopsy, and the metabolic imaging with hybrid PET/CT and MRI/CT. It particularly highlights the emerging strategies in therapy, surgery and mini-invasive surgery as well as loco-regional and systemic treatments, including targeted therapy and/or biological therapies. The second part then explores the management of NENs of various anatomical origins and/or with peculiar biology. It describes the range of the current options and the most relevant results from the clinical trials. This informative book provides valuable insights for all those interested in the management of neuroendocrine neoplasia.
Gastroenteropancreatic Neuroendocrine Tumor Disease
Author: Bertram Wiedenmann
Publisher:
Published: 2004
Total Pages: 320
ISBN-13:
DOWNLOAD EBOOK →At the beginning of the last century, the development of the Neuroendocrine Concept sparked intensive and worldwide research efforts leading to fascinating insights into the complex and diverse system of neuroendocrine cells and its importance in human physiology and disease. Recent developments in new and expanding research areas, including developmental biology, regulation of angiogenesis, cellular signaling and transcription, and impressive results obtained by application of genomics and proteomics warranted a reevaluation of the neuroendocrine concept. impact of the current understanding of neuroendocrine biology and pathobiology in these research areas. In particular, new discoveries are presented in neuroendocrine developmental biology with special emphasis on transcription factors controlling neuroendocrine differentiation of endodermal stem cells. controlling formation and proliferation of blood and lymphatic vessels and molecular determinants of hematogenous and lymphatic tumor dissemination. Given their central importance for the establishment and maintenance of the neuroendocrine phenotype, signal transduction cascades and their cellular targets related to the regulation of adhesion processes, receptor-mediated endocytosis, and cell cycle events as well as secretory activation and membrane trafficking are discussed in the context of neuroendocrine physiology and neuroendocrine tumor disease. Since many of the recent discoveries made in basic research can be directly linked to clinical applications, this volume summarizes and discusses innovative treatment and/or diagnostic approaches for neuroendocrine tumor disease.
