Nematode Models of Development and Disease

Nematode Models of Development and Disease PDF

Author:

Publisher: Academic Press

Published: 2021-05-13

Total Pages: 452

ISBN-13: 0128161787

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Nematode Models of Development and Disease, Volume 144 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters surrounding Transgenerational inheritance, Oscillatory expression and function, Concepts and functions of small RNA pathways in C. elegans, Exploring the nuclear lamina in health and pathology using C. elegans, Cellular Plasticity, Morphogenesis, Tubulogenesis, Organogenesis forces, Programmed cell fusion in development and homeostasis, One template, two outcomes: how does the sex-shared nervous system generate sex-specific behaviors?, Metabolic Cellular Coordination of Gene-Environment Interactions, and much more. Other chapters cover Chemical and physical cues and micro-evolution in early embryogenesis, Innate immunity, Sex and Death, Dendrites maturation, axonal growth and extracellular glycoproteins, Autophagocytosis, Spermatogenesis, and the developmental and physiological roles of phagocytosis in Caenorhabditis elegans. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology

C. Elegans II

C. Elegans II PDF

Author: Donald L. Riddle

Publisher: Firefly Books

Published: 1997

Total Pages: 1252

ISBN-13: 9780879695323

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Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR

Nematodes as Model Organisms

Nematodes as Model Organisms PDF

Author: Itamar Glazer

Publisher: Cab International

Published: 2022

Total Pages: 0

ISBN-13: 9781789248814

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"Nematodes, especially Caenorhabditis elegans have been used as a model for research in molecular biology since the 1960's. This is a much-needed update on research on fundamental processes in areas such as genetics, developmental biology, nutrition, toxicology, ecology, pharmacology and medicine"--

Methods of Behavior Analysis in Neuroscience

Methods of Behavior Analysis in Neuroscience PDF

Author: Jerry J. Buccafusco

Publisher: CRC Press

Published: 2000-08-29

Total Pages: 341

ISBN-13: 1420041819

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Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Scientific Frontiers in Developmental Toxicology and Risk Assessment PDF

Author: National Research Council

Publisher: National Academies Press

Published: 2000-12-21

Total Pages: 348

ISBN-13: 0309070864

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Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

The Biology of Nematodes

The Biology of Nematodes PDF

Author: Donald L Lee

Publisher: CRC Press

Published: 2002-01-10

Total Pages: 648

ISBN-13: 0203166434

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The Biology of Nematodes synthesizes knowledge of the biology of free-living, plant-parasitic, and animal-parasitic nematodes. Contributed works by recognized researchers apply groundbreaking molecular techniques, many of which resulted from work on Caenorhabditis elegans, toward new approaches to the study of nematode worms. Topics covered include: ̈ Systematics and phylogeny ̈ Neuromuscular physiology ̈ Locomotion ̈ Sense organs ̈ Behavior ̈ Aging ̈ The nematode genome ̈ Survival strategies ̈ Immunology ̈ Epidemiology ̈ Structure and organization ̈ Gametes and fertilization ̈ Development ̈ Feeding, digestion, and metabolism

Inborn Errors of Development

Inborn Errors of Development PDF

Author: Charles J. Epstein

Publisher: Oxford University Press, USA

Published: 2004

Total Pages: 1110

ISBN-13: 019514502X

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In this book, the clinical chapters are organized into sections by defined developmental pathways or gene families, and each section is preceded by a general overview. For each disorder the authors cover the disease-causing genes, the role of these genes in development as elucidated in model organisms, the human mutations that have been identified, and the developmental pathogenesis of the condition. Clinical descriptions, along with discussions of therapy and counseling, are provided. This book will be an invaluable resource for physicians, dentists, and other health professionals and for basic scientists interested in developmental processes and genetic perturbations that affect them.

Caenorhabditis Elegans

Caenorhabditis Elegans PDF

Author: Daiana S. Avila

Publisher:

Published: 2019

Total Pages: 0

ISBN-13: 9781536149463

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Caenorhabditis elegans - An Overview and Emerging Roles in Studying Disease explores different disease models that have been successfully validated in this nematode, either to unravel disease mechanisms or to perform drug screenings. This nonpathogenic organism has helped to firstly identify genetic mechanisms important in cancer (Ras and Bcl oncogene signaling), aging (insulin signaling), and nervous system development (UNC-6/Netrin signaling). Human conditions such as aging/frailty (Chapter One), metabolic syndrome (Chapter Two), neurodegenerative diseases (Chapters Three and Four) and neurodegeneration induced by chemicals (Chapters Three and Five) are recapitulated in C. elegans. The construction of transgenic animals that mimic the diseases, the advances in understanding molecularly these conditions, potential new treatments and limitations of the models are reviewed in these chapters. Notably, the authors that contributed to this book are from different parts of the world due to the widespread use of this nematode in research.

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