Nanoneuroprotection and Nanoneurotoxicology

Nanoneuroprotection and Nanoneurotoxicology PDF

Author:

Publisher: Academic Press

Published: 2019-04-06

Total Pages: 324

ISBN-13: 0444642099

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Nanoneuroprotection and Nanoneurotoxicology, Volume 245, deals with recent developments in the field of neurotoxicity and neuroprotection using nanobiotechnology for the first time. Chapters in this updated release include Sleep deprivation induced brain pathology and concussive head trauma-Neuroprotective effects of nanowired delivery of drugs and hormones, Nanomedicine in Alzheimer’s Disease: amyloid beta targeting strategy, How traumatic brain injury alters amino acids balance in the central nervous system-Neuroprotection by TiO2 nanowired delivery of drugs and antibodies, Nanowired delivery of DL-3-n-butylphthalide and neuroprotection in concussive head injury, Nanodelivery of drugs and antibodies for superior neuroprotection in Alzheimer’s disease, and more. Highlights recent development in nanopharmacetical research with reference to brain disease Provides new insights on the possible role of nanomaterials and their pronounced effects on CNS injury or repair

Neurotoxicity of Nanomaterials and Nanomedicine

Neurotoxicity of Nanomaterials and Nanomedicine PDF

Author: Xinguo Jiang

Publisher: Academic Press

Published: 2016-10-03

Total Pages: 368

ISBN-13: 0128046201

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Neurotoxicity of Nanomaterials and Nanomedicine presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation. This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials. Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials. Presents a thorough discussion of the most common nanoparticles in the brain and their neurotoxicology Includes the most common nanoparticles, their applications, and mechanisms Provides one of the first books to focus on nanomedicine and neurotoxicity

Natural Molecules in Neuroprotection and Neurotoxicity

Natural Molecules in Neuroprotection and Neurotoxicity PDF

Author: Marcos Roberto de Oliveira

Publisher: Elsevier

Published: 2023-11-24

Total Pages: 2202

ISBN-13: 0443237646

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Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease. Covers both neuroprotective and neurotoxic outcomes resulted from the exposure of brain cells to natural molecules Analyzes numerous natural compounds, including animal, vegetal, fungal, bacterial, and marine-derived molecules Discusses the effects of the metabolism of microbiota on the biotransformation of natural molecules and the consequences of these processes on brain cells Contains a section focused on the nanotechnology-related strategies utilized to enhance the bioavailability of natural molecules to brain cells

Drug and Gene Delivery to the Central Nervous System for Neuroprotection

Drug and Gene Delivery to the Central Nervous System for Neuroprotection PDF

Author: Hari S. Sharma

Publisher: Springer

Published: 2017-06-05

Total Pages: 237

ISBN-13: 3319576968

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This book summarizes the latest research on drug and gene delivery to the central nervous system (CNS). The chapters address safety concerns regarding the nanotechnology that is needed to develop nanomedicine for clinical practice. Particular focus is given to new technologies that have emerged in recent years to deliver therapeutic materials, such as genes, drugs, and other agents using nanotechnologies of diverse origin. This is an ideal book for students, teachers, researchers, and clinicians interested in a deeper understanding of nanotechnological advances in therapeutic medicine. This book also: Broadens readers’ understanding of viral vector gene delivery to the brain for treating neurogenetic diseases as well as targeted gene delivery into the brain using microbubble-facilitated focused ultrasound Covers in detail the latest developments in delivering therapeutic materials, such as siRNA delivery to the brain for treating neurological diseases, neuroprotective effects of gelatin nanoparticles in stroke, and nanowired drug delivery for brain diseases, heat stroke, and CNS injury Enriches understanding of new technologies for delivering therapeutic materials treating Alzheimer’s Disease, including targeted nanodrug delivery through the blood-brain barrier and the superior neuroprotective effects of nanowired drug delivery in Alzheimer’s Disease

Nanomedicine and Neuroprotection in Brain Diseases

Nanomedicine and Neuroprotection in Brain Diseases PDF

Author: Hari Shanker Sharma

Publisher: Elsevier

Published: 2021-09-22

Total Pages: 444

ISBN-13: 0323901638

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Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Brain Research series Updated release includes the latest information on the Neuropharmacology of Neuroprotection

Brain Targeted Drug Delivery Systems

Brain Targeted Drug Delivery Systems PDF

Author: Huile Gao

Publisher: Academic Press

Published: 2018-09-20

Total Pages: 499

ISBN-13: 012814002X

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Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain. Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers Discusses key points in developing brain targeting drug delivery systems Summarizes and presents currently available strategies for brain targeting drug delivery Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research

Nanoneuroscience and Nanoneuropharmacology

Nanoneuroscience and Nanoneuropharmacology PDF

Author: Hari S. Sharma

Publisher: Elsevier

Published: 2009-12-03

Total Pages: 261

ISBN-13: 0080962246

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This volume presents articles from the leading experts in the field in nanobiotechnology, providing students and researchers with a comprehensive review of the newly emerging area of neuroscience. All aspects of nanomaterials induced alteration in brain function are considered. Basic chapters on methods and ways to enhance nano-drug delivery into the brain are presented as well as chapters on functional and structural changes in the CNS, including gene expression and related issues. Particular attention is given to possible therapeutic advancement regarding nano-drug formulation and their role in neuroprotection.

Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors Part A

Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors Part A PDF

Author:

Publisher: Elsevier

Published: 2023-10

Total Pages: 362

ISBN-13: 0323997775

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Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors, Volume 171 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on Neurodegenerative diseases, Stress induced exacerbation of Alzheimer's disease brain pathology is thwarted by co-administration of nanowired cerebrolysin and amyloid beta peptide antibodies with serotonin 5-HT6 receptor antagonist SB-39988, Nanowired delivery of dl-3-n-butylphthalide with antibodies to alpha synuclein potentiated neuroprotection in Parkinson's disease with emotional stress, Efficacy of invasive and non-invasive methods for the treatment of Parkinson ́s disease: nanodelivery and enriched environment, and much more. Other sections cover Sleep deprivation induced exacerbation of Parkinson's disease pathophysiology is attenuated by co-administration of nanowired cerebrolysin and serotonin-3 receptor antagonist ondansetron, Co-administration of DL-3-n-butylphthalide and neprilysin is neuroprotective in Alzheimer disease associated with brain injury, Stress and brain diseases, Pathophysiology of sleep deprivation enhances amyloid beta peptide and p-tau in the CSF and brain, Neuroprotective effects of nanowired delivery of multimodal drug cerebrolysin and monoclonal 5-HT antibodies, Prior heat exposure exacerbates brain blast injury, Neuroprotection by nanodelivery of cerebrolysin with serotonin 6 receptor antagonist SB-399885, the Effects of curcumin nanodelivery on several brain pathologies, and more.

Inorganic Nanoparticles

Inorganic Nanoparticles PDF

Author: Claudia Altavilla

Publisher: CRC Press

Published: 2017-12-19

Total Pages: 885

ISBN-13: 1351833960

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Among the various nanomaterials, inorganic nanoparticles are extremely important in modern technologies. They can be easily and cheaply synthesized and mass produced, and for this reason, they can also be more readily integrated into applications. Inorganic Nanoparticles: Synthesis, Applications, and Perspectives presents an overview of these special materials and explores the myriad ways in which they are used. It addresses a wide range of topics, including: Application of nanoparticles in magnetic storage media Use of metal and oxide nanoparticles to improve performance of oxide thin films as conducting media in commercial gas and vapor sensors Advances in semiconductors for light-emitting devices and other areas related to the energy sector, such as solar energy and energy storage devices (fuel cells, rechargeable batteries, etc.) The expanding role of nanosized particles in the field of catalysis, art conservation, and biomedicine The book’s contributors address the growing global interest in the application of inorganic nanoparticles in various technological sectors. Discussing advances in materials, device fabrication, and large-scale production—all of which are urgently required to reduce global energy demands—they cover innovations in areas such as solid-state lighting, detailing how it still offers higher efficiency but higher costs, compared to conventional lighting. They also address the impact of nanotechnology in the biomedical field, focusing on topics such as quantum dots for bioimaging, nanoparticle-based cancer therapy, drug delivery, antibacterial agents, and more. Fills the informational gap on the wide range of applications for inorganic nanoparticles in areas including biomedicine, electronics, storage media, conservation of cultural heritage, optics, textiles, and cosmetics Assembling work from an array of experts at the top of their respective fields, this book delivers a useful analysis of the vast scope of existing and potential applications for inorganic nanoparticles. Versatile as either a professional research resource or textbook, this effective tool elucidates fundamentals and current advances associated with design, characterization, and application development of this promising and ever-evolving device.

Cardiovascular Effects of Inhaled Ultrafine and Nano-Sized Particles

Cardiovascular Effects of Inhaled Ultrafine and Nano-Sized Particles PDF

Author: Flemming R. Cassee

Publisher: John Wiley & Sons

Published: 2011-03-29

Total Pages: 490

ISBN-13: 047092277X

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This book assists scientists, toxicologists, clinicians, and public health regulators to understand the complex issues that determine the impact of air pollution on the cardiovascular system. It covers a range of relevant topics including particulate matter (PM) sources and characterization, methods of exposure, impact of PM on cells and systems, role of particles in the pathophysiology of cardiovascular disease, risk assessment, and potential environmental and therapeutic interventions.