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MRI-Guided Focused Ultrasound Surgery

Author: Ferenc A. Jolesz

Publisher: CRC Press

Published: 2007-09-26

Total Pages: 217

ISBN-13: 1420019937

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Mri-Guided Focused Ultrasound Surgery

Author: Ferenc A Jolesz

Publisher: CRC Press

Published: 2019-08-30

Total Pages: 216

ISBN-13: 9780367388560

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MRI-Guided Focused Ultrasound Surgery will be the first publication on this new technology, and will present a variety of current and future clinical applications in tumor ablation treatment. This source helps surgeons and specialists evaluate, analyze, and utilize MRI-guided focused ultrasound surgery - bridging the gap between phase 3 clinical trials and the expansion to the clinical practice - by exploring fundamental principles and future clinical applications using this new therapeutic method.

The Tumor

Author: John Grisham

Publisher: Focused Ultrasound Foundation

Published: 2015-03

Total Pages: 66

ISBN-13: 1495179419

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John Grisham says THE TUMOR is the most important book he has ever written. In this short book, he provides readers with a fictional account of how a real, new medical technology could revolutionize the future of medicine by curing with sound. THE TUMOR follows the present day experience of the fictional patient Paul, an otherwise healthy 35-year-old father who is diagnosed with a malignant brain tumor. Grisham takes readers through a detailed account of Paul’s treatment and his family’s experience that doesn’t end as we would hope. Grisham then explores an alternate future, where Paul is diagnosed with the same brain tumor at the same age, but in the year 2025, when a treatment called focused ultrasound is able to extend his life expectancy. Focused ultrasound has the potential to treat not just brain tumors, but many other disorders, including Parkinson’s, Alzheimer’s, hypertension, and prostate, breast and pancreatic cancer. For more information or to order a free hardcopy of the book, please visit The Focused Ultrasound Foundation’s website www.fusfoundation.org. Here you will find a video of Grisham on the TEDx stage with the Foundation’s chairman and a Parkinson’s patient who brings the audience to its feet sharing her incredible story of a focused ultrasound “miracle.” Readers will get a taste of the narrative they expect from Grisham, but this short book will also educate and inspire people to be hopeful about the future of medical innovation.

Image-guided Focused Ultrasound Therapy

Author: Feng Wu

Publisher: CRC Press

Published: 2024-07-31

Total Pages: 503

ISBN-13: 1498711367

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Ultrasound has been widely used in diagnostic imaging for a long time. In the past 10 years, image-guided focused ultrasound therapy has seen rapid growth, in biomedical science and engineering, and in clinical medicine. The purpose of this book is to bring internationally renowned authorities and experts in this field together to provide up-to-date and comprehensive reviews of basic physics, biomedical engineering, and clinical applications of focused ultrasound therapy in a widely accessible fashion. Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of focused ultrasound therapy. It reviews the medical physics and bio-effects of focused ultrasound beams on living tissues, dosimetric methods and measurements, transducer engineering, image guidance and monitoring (including magnetic resonance imaging -- MRI -- and ultrasound), treatment delivery systems, and clinical applications. The book also gives practical guidelines on patient setup, target localisation, treatment planning and image-guided procedures for the treatment in various sites, including the prostate, liver, pancreas, breast, kidney, uterus, bone, and brain. The book discusses major challenges for the use of focused ultrasound energy on living tissues and explores the cellular and physiological responses that can be employed in the fight against cancer from biological, physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumours using image-guided drug delivery, and the exploitation of microbubbles, nanoparticles, and other cutting-edge techniques. Readers who are interested in learning more about the technique and the clinical applications described in each chapter can find more information in the comprehensive bibliographies provided. This book is suitable for anyone involved in, or looking to become involved in, the research and clinical applications of focused ultrasound therapy, including medical professionals, physicists, biomedical engineers, graduate students and others working in this multidisciplinary field. It offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and an outlook on the future of focused ultrasound therapy. It presents a thorough introduction for those new to the field while providing helpful, up-to-date information and guidelines for readers already using this therapy in clinical and pre-clinical settings. Key Features: Brings together a wide range of world-leading experts in this new field, presenting the latest clinical outcomes of using focused ultrasound for the treatment of benign and malignant diseases Covers the fundamental physics of focused ultrasound therapy and ultrasound-mediated drug delivery, including chapters on the mechanism of sonoporation, microbubble and ultrasound interaction, and their potential clinical applications Introduces clinical guidelines for focused ultrasound therapy, including indications and contraindications, treatment goals, the selection of patients, clinical observation during treatment procedure and follow-up, and characteristics of image changes after treatment

Theranostics and Image Guided Drug Delivery

Author: Maya Thanou

Publisher: Royal Society of Chemistry

Published: 2018-01-02

Total Pages: 254

ISBN-13: 178801393X

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Molecular imaging of drugs or drug carriers is a valuable tool that can provide important information on spatiotemporal distribution of drugs, allowing improved drug distribution at target sites. Chemically labelled drugs can be used to both diagnose and treat diseases. This book introduces the topic of image guided drug delivery and covers the latest imaging techniques and developments in theranostics, highlighting the interdisciplinary nature of this field as well as its translational ability. These technologies and techniques hold potential for individualised, safer therapies. The book introduces the chemistry behind labelling drugs or drug carriers for imaging. It then discusses current scientific progress in the discovery and development of theranostic agents as well as the latest advances in triggered drug delivery. Novel imaging techniques that can be combined with therapeutics are presented, as well as results and findings from early clinical trials. This text will provide postgraduates and researchers in various disciplines associated with drug discovery, including chemistry, device engineering, oncology, neurology, cardiology, imaging, and nanoscience, an overview of this important field where several disciplines have been combined to improve treatments. Readers will be introduced to techniques that can be translated to the clinic and be applied widely.

Image-Guided Neurosurgery

Author: Alexandra J. Golby

Publisher: Academic Press

Published: 2015-05-05

Total Pages: 536

ISBN-13: 0128011890

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Image-Guided Neurosurgery provides readers with an update on the revolutionary improvements in imaging and visualization relating to neurosurgery. From the development of the pneumoencephalogram, to the operating microscope, to cross sectional imaging with CT and later MRI, to stereotaxy and neuronavigation, the ability to visualize the pathology and surrounding neural structures has been the driving factor leading surgical innovation and improved outcomes. The book provides a comprehensive reference on the application of contemporary imaging technologies used in neurosurgery. Specific techniques discussed include brain biopsies, brain tumor resection, deep brain stimulation, and more. The book is ideal for neurosurgeons, interventional radiologists, neurologists, psychiatrists, and radiologists, as well as technical experts in imaging, image analysis, computer science, and biomedical engineering. A comprehensive reference on image-guided neurosurgery Includes coverage of neuronavigation in cranial surgery and advanced imaging, including functional imaging, adoption of intra-operative MRI and emerging technologies Covers all image-guided neurosurgery tools, including robotic surgical devices Ideal reference for topics relating to neurosurgery, imaging, stereotaxis, radiosurgery, radiology, epilepsy, MRI, the use of medical robotics, lasers, and more

MR-Guided Interventions, An Issue of Magnetic Resonance Imaging Clinics of North America 23-4,

Author: Clare M. Tempany

Publisher: Elsevier Health Sciences

Published: 2016-01-07

Total Pages:

ISBN-13: 0323413390

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Guest editors Claire Tempany and Tina Kapur review MR-Guided Interventions in this important issue in MRI Clinics of North America. Articles include: MR sequences and rapid acquisition for MR-guided interventions; MR-guided breast interventions: role in biopsy targeting and lumpectomies; MR-guided passive catheter tracking for endovascular therapy; MRgFUS update on clinical applications; MR-guided spine Interventions; MR-guided prostate biopsy; Interventional MRI Clinic: the Emory experience; MR-guided cardiac interventions; MR-guided functional neurosurgery; MR-guided active catheter tracking; MR-guided drug delivery; MR-guided thermal therapy for localized and recurrent prostate cancer; MR neurography for guiding nerve blocks and its role in pain management; MR-guided gynecologic brachytherapy; and more!

Intraoperative Imaging and Image-Guided Therapy

Author: Ferenc A. Jolesz

Publisher: Springer Science & Business Media

Published: 2014-01-14

Total Pages: 870

ISBN-13: 1461476577

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Image-guided therapy (IGT) uses imaging to improve the localization and targeting of diseased tissue and to monitor and control treatments. During the past decade, image-guided surgeries and image-guided minimally invasive interventions have emerged as advances that can be used in place of traditional invasive approaches. Advanced imaging technologies such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) entered into operating rooms and interventional suites to complement already-available routine imaging devices like X-ray and ultrasound. At the same time, navigational tools, computer-assisted surgery devices, and image-guided robots also became part of the revolution in interventional radiology suites and the operating room. Intraoperative Imaging and Image-Guided Therapy explores the fundamental, technical, and clinical aspects of state-of the-art image-guided therapies. It presents the basic concepts of image guidance, the technologies involved in therapy delivery, and the special requirements for the design and construction of image-guided operating rooms and interventional suites. It also covers future developments such as molecular imaging-guided surgeries and novel innovative therapies like MRI-guided focused ultrasound surgery. IGT is a multidisciplinary and multimodality field in which teams of physicians, physicists, engineers, and computer scientists collaborate in performing these interventions, an approach that is reflected in the organization of the book. Contributing authors include members of the National Center of Image-Guided Therapy program at Brigham and Women’s Hospital and international leaders in the field of IGT. The book includes coverage of these topics: - Imaging methods, guidance technologies, and the therapy delivery systems currently used or in development. - Clinical applications for IGT in various specialties such as neurosurgery, ear-nose-and-throat surgery, cardiovascular surgery, endoscopies, and orthopedic procedures. - Review and comparison of the clinical uses for IGT with conventional methods in terms of invasiveness, effectiveness, and outcome. - Requirements for the design and construction of image-guided operating rooms and interventional suites.

Image-Guided Cancer Therapy

Author: Damian E. Dupuy

Publisher: Springer

Published: 2013-08-06

Total Pages: 0

ISBN-13: 9781441907509

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Image-Guided Cancer Therapy: A Multidisciplinary Approach provides clinicians with in-depth coverage of the growing, dynamic field of interventional oncology. Combining the knowledge of expert editors and authors into one powerhouse reference, this book looks at tumor ablation, HIFU, embolic therapies, emerging technologies, and radiation therapy throughout the body (liver, bone, breast, gynecologic and prostate cancers, to name just a few) , and includes discussion of different imaging modalities. In the words of Peter Mueller, MD, author of the book’s Foreword: “... The senior authors are all world renowned experts in interventional oncology, which is another example of the high quality authorship and experience that is brought to this book. The later chapters discuss therapies that are simply not covered in any other source. Everyone who is doing or wants to do ablation therapies and interventional oncology will face a time when they will be asked to use their expertise in less used and less investigated areas. There is nowhere else where the reader can get information on the prostate, breast, and gynecologic areas, and especially pediatrics....This book is an outstanding contribution to the literature and will become a ‘must read’ for all physicians who are interested in Interventional Oncology.”

Surgery for Parkinson's Disease

Author: Robert R. Goodman

Publisher: Springer

Published: 2018-12-28

Total Pages: 178

ISBN-13: 3319236938

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Deep brain stimulation for the treatment of patients with Parkinson’s disease was introduced in the 1990s. Initially performed only at academic centers, over the past decade it has become a widespread surgical procedure. A variety of surgical techniques are employed and innovations are introduced frequently. This book is an ideal source of information for the many practicing neurosurgeons who did not learn this surgery during their training but would now like to add it to their practice, as well as an excellent update on exciting new developments in surgery for Parkinson’s disease. This book is designed to provide practicing neurosurgeons with current knowledge on the practical aspects of surgical treatment of patients with Parkinson’s disease. It explains how to identify surgical candidates and determine the optimal surgery, describes the various surgical techniques that are currently employed, and offers insights into how to optimize deep brain stimulation therapy after implantation. The keys to avoidance of surgical complications are carefully elucidated. In addition, an overview is provided of potential advances on the near-term horizon, including closed-loop deep brain stimulation, gene therapy, and optogenetics. All topics are covered by experienced Parkinson’s disease surgeons, in a concise and digestable format. The book will be an ideal source of information for the many practicing neurosurgeons who would like to add deep brain stimulation to their practice, as well as an excellent update on new developments in surgery for Parkinson’s disease.