Molecular and Cellular Therapies for Motor Neuron Diseases

Molecular and Cellular Therapies for Motor Neuron Diseases PDF

Author: Nicholas M Boulis

Publisher: Academic Press

Published: 2017-01-18

Total Pages: 337

ISBN-13: 0128025247

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Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials. Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy

Motor Neuron Disease in Adults

Motor Neuron Disease in Adults PDF

Author: Mark B. Bromberg

Publisher: Contemporary Neurology

Published: 2014-10-28

Total Pages: 369

ISBN-13: 019978311X

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'Motor Neuron Disease in Adults' reviews new information from 1998 as it applies to all aspects of motor neuron disease. Articles included use evidence-based methods to ensure that the new information is solid and advances the topic. The book can be used by anyone who provides any type of care to ALS patients.

Living with Motor Neurone Disease

Living with Motor Neurone Disease PDF

Author: Marie Murray Marie

Publisher: Atrium

Published: 2021-10

Total Pages:

ISBN-13: 9781782054832

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Living with Motor Neurone Disease: A complete guide is designed to guide the reader through this complex progressive neurological condition that attacks the motor neurones, or nerves, in the brain and spinal cord. This means that messages gradually stop reaching the muscles, which leads to weakness and wasting. Motor Neurone Disease can affect the everyday things that we take for granted. A diagnosis of MND can be frightening and overwhelming. Good quality information and support from people who understand MND is vital at this time. Living with Motor Neurone Disease is written by many of the most distinguished Irish experts on MND, bringing safe, reliable, practical information and reassurance to everyone affected by Motor Neurone Disease. Having accurate information and timely access to the best available services including doctors, neurologists, MND outreach nurses and local community healthcare professionals makes all the difference when it comes to a person's journey with MND. This is a step-by-step guide for everyone which explains what MND is; how it is diagnosed; how it affects the individual and the family; the psychological dimensions of the condition; the caregiver experience; living with the condition and facing the future; how to talk to children and adolescents; how to tell family and friends; how to adapt working conditions and home life; and it describes all the supports; medical, psychological technological and practical to cope with the daily impact of living with MND. In summary, it is an invaluable resource to inform, educate prepare and signpost people toward practical everyday supports and clinical expertise. Living with Motor Neurone Disease: A complete guide is a must-read for professionals; for doctors, nurses, educationalists, for psychologists, systemic family therapists and psychotherapists, those working in human resources and everyone who needs to understand the condition when they encounter it.

Motor Neuron Disease

Motor Neuron Disease PDF

Author: P.N. Leigh

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 477

ISBN-13: 1447118715

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Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.

Palliative Care in Amyotrophic Lateral Sclerosis

Palliative Care in Amyotrophic Lateral Sclerosis PDF

Author: David Oliver

Publisher: OUP Oxford

Published: 2014-03-20

Total Pages: 353

ISBN-13: 0191509507

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Amytrophic Lateral Sclerosis (ALS or motor neurone disease) is a progressive neurodegenerative disease that can cause profound suffering for both the patient and their family. Whilst new treatments for ALS are being developed, these are not curative and offer only the potential to slow its progression. Palliative care must therefore be integral to the clinical approach to the disease. Palliative Care in Amyotrophic Lateral Sclerosis: From diagnosis to bereavement reflects the wide scope of this care; it must cover not just the terminal phase, but support the patient and their family from the onset of the disease. Both the multidisciplinary palliative care team and the neurology team are essential in providing a high standard of care and allowing quality of life (both patient and carer) to be maintained. Clear guidelines are provided to address care throughout the disease process. Control of symptoms is covered alongside the psychosocial care of patients and their families. Case studies are used to emphasise the complexity of the care needs and involvement of the patient and family, culminating in discussion of bereavement. Different models of care are explored, and this new edition utilizes the increase in both the evidence-base and available literature on the subject. New topics discussed include complementary therapies, personal and family experiences of ALS, new genetics research, and updated guidelines for patient care, to ensure this new edition remains the essential guide to palliative care in ALS.

Motor Neuron Disease

Motor Neuron Disease PDF

Author: Kevin Talbot

Publisher: Oxford University Press

Published: 2010

Total Pages: 228

ISBN-13: 019954736X

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Written and designed to provide comprehensive, easily accessible advice for all healthcare professionals involved in the care of patients with this challenging condition, this book addresses the entire care pathway from presentation to diagnosis to symptom management and end of life issues.

Practical Guide to Neurogenetics E-Book

Practical Guide to Neurogenetics E-Book PDF

Author: Thomas T. Warner

Publisher: Elsevier Health Sciences

Published: 2008-11-04

Total Pages: 343

ISBN-13: 0702038458

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This simple guide to neurogenetics demystifies the overwhelming amount of information on the subject so you can identify key clinical features and understand your management options. Reach relevant differential diagnoses and provide appropriate counseling to your patients using the symptom-based approach. By integrating genetic and neurological approaches to diagnoses, this book ensures that the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis are clear and explicit. Concise and portable, this book is ideal for easy reference in clinical use. Details the underlying basic science and clinical features of genetic disorders by taking a symptom-based approach to provide you with a comprehensive understanding of the field. Focuses on the clinical application of neurogenetics to be of practical use to you in the clinic. Clarifies the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis by integrating genetic and neurological approaches to diagnoses. Discusses and evaluates necessary investigations so you know when to use them and when to refer. Highlights diagnostic and therapeutic tips so you can learn new concepts or refine your skills in practice. Refers to online sources, such as Online Mendelian Inheritance in Man (OMIM) and others, to help you supplement your knowledge.

Electromyography and Neuromuscular Disorders E-Book

Electromyography and Neuromuscular Disorders E-Book PDF

Author: David C. Preston

Publisher: Elsevier Health Sciences

Published: 2012-12-01

Total Pages: 663

ISBN-13: 1455744735

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Diagnose neuromuscular disorders more quickly and accurately with Electromyography and Neuromuscular Disorders: Clinical-Electrophysiologic Correlations, 3rd Edition! State-of-the-art guidance helps you correlate electromyographic and clinical findings and use the latest EMG techniques to their fullest potential. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Successfully correlate electrodiagnostic findings with key clinical findings for more confident diagnoses. Clearly see how to apply what you’ve learned with abundant case studies throughout the book. Obtain relevant clinical guidance quickly and easily with an accessible, easy-to-read writing style that’s both comprehensive and easy to understand. Ensure correct EMG needle placement and avoid neurovascular injuries by referring to more than 65 detailed, cross-sectional anatomy drawings. Diagnose many newly defined genetic neuromuscular conditions based on their electrodiagnostic presentation. Stay up to date with must-know information on iatrogenic complications of electrodiagnostic studies. Visualize key concepts more easily with a brand-new full-color design, new artwork, and new photographs. Access Electromyography and Neuromuscular Disorders online, fully searchable, at www.expertconsult.com, along with more than 70 videos that allow you to see and hear the EMG waveforms discussed in the text, as well as a convenient "test yourself" module.

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