Molecular Imaging in Multiple Myeloma

Molecular Imaging in Multiple Myeloma PDF

Author: Cristina Nanni

Publisher: Springer

Published: 2019-07-02

Total Pages: 136

ISBN-13: 3030190196

DOWNLOAD EBOOK →

This book provides a comprehensive overview of the importance of molecular imaging in multiple myeloma, with detailed explanation of its clinical impact. Other important features are the definition of criteria that will aid PET/CT interpretation; identification and explanation of the most frequent pitfalls; a brief overview of the advantages and limitations of DWI MR imaging, still an experimental technique in multiple myeloma; and examination of the possible role of emerging PET tracers. When appropriate, clinical cases are used to illustrate key teaching points. All physicians involved in oncological imaging should regularly reassess and update their routine practice in the evaluation of multiple myeloma patients. This is especially true now, given the recent clarification by the International Myeloma Working Group (IMWG) of the criteria for bone damage requiring therapy and the emerging data supporting the role of the newer functional imaging techniques in predicting outcome and/or evaluating response to therapy. In this challenging context, Molecular Imaging in Multiple Myeloma will be of high value for nuclear medicine physicians, radiologists, and hematologists.

Magnetic Resonance Imaging of the Bone Marrow

Magnetic Resonance Imaging of the Bone Marrow PDF

Author: Andrea Baur-Melnyk

Publisher: Springer Science & Business Media

Published: 2012-12-13

Total Pages: 375

ISBN-13: 364217860X

DOWNLOAD EBOOK →

On account of its unrivalled imaging capabilities and sensitivity, magnetic resonance imaging (MRI) is considered the modality of choice for the investigation of physiologic and pathologic processes affecting the bone marrow. This book describes the MRI appearances of both the normal bone marrow, including variants, and the full range of bone marrow disorders. Detailed discussion is devoted to malignancies, including multiple myeloma, lymphoma, chronic myeloproliferative disorders, leukemia, and bone metastases. Among the other conditions covered are benign and malignant compression fractures, osteonecrosis, hemolytic anemia, Gaucher’s disease, bone marrow edema syndrome, trauma, and infective and non-infective inflammatory disease. Further chapters address the role of MRI in assessing treatment response, the use of contrast media, and advanced MRI techniques. Magnetic Resonance Imaging of the Bone Marrow represents an ideal reference for both novice and experienced practitioners.

Multiple Myeloma

Multiple Myeloma PDF

Author: Morie A. Gertz

Publisher: Springer Science & Business Media

Published: 2013-10-01

Total Pages: 311

ISBN-13: 1461485207

DOWNLOAD EBOOK →

This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.

Nuclear Oncology

Nuclear Oncology PDF

Author: H. William Strauss

Publisher: Springer Science & Business Media

Published: 2012-11-27

Total Pages: 873

ISBN-13: 0387488944

DOWNLOAD EBOOK →

This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.

Update on Multiple Myeloma

Update on Multiple Myeloma PDF

Author: Khalid Ahmed Al-Anazi

Publisher:

Published: 2019-02

Total Pages: 236

ISBN-13: 178985217X

DOWNLOAD EBOOK →

This book is a comprehensive overview of the recent developments in the clinical and research fields of multiple myeloma. It is divided into three main sections that cover a wide range of topics, including: epidemiology and pathogenesis of the disease, genetic targets and pathways, resistance to novel therapies, angiogenesis and anti-angiogenesis, hematopoietic stem cell transplantation, role of radiology and radiotherapy in myeloma, infectious complications, and management of multiple myeloma in resource-poor countries.

Musculoskeletal Imaging: The Requisites

Musculoskeletal Imaging: The Requisites PDF

Author: B. J. Manaster

Publisher: Elsevier Health Sciences

Published: 2013-03-15

Total Pages: 603

ISBN-13: 0323081770

DOWNLOAD EBOOK →

Musculoskeletal Imaging: The Requisites, 4th Edition delivers the conceptual, factual, and interpretive information you need for effective clinical practice in musculoskeletal imaging, as well as for certification and recertification review. Master core knowledge the easy and affordable way with clear, concise text enhanced by at-a-glance illustrations, boxes, and tables - all completely rewritten to bring you up to date. Find key information easily with numerous outlines, tables, "pearls," and boxed material for easy reading and reference. Access the fully searchable text and downloadable images online at www.expertconsult.com. Get the best results from today's most technologically advanced approaches, including new uses of MR and ultrasound for early diagnosis and monitoring of inflammatory arthritis. Prepare for the written board exam and for clinical practice with critical information on femoroacetabular impingement, arthrography, hip replacement, cartilage tumors, bone marrow imaging (including focal and diffuse replacement), and sports medicine (including athletic pubalgia/sports hernia). Stay up to date on soft tissue tumors with significantly expanded content, illustrated tumor-specific findings, and new AJCC staging and diagnostic information. Clearly visualize the findings you're likely to see in practice and on exams with 300 new MRI, CT, ultrasound, and x-ray images throughout.

Boron-Based Compounds

Boron-Based Compounds PDF

Author: Evamarie Hey-Hawkins

Publisher: John Wiley & Sons

Published: 2018-07-23

Total Pages: 490

ISBN-13: 1119275555

DOWNLOAD EBOOK →

Noted experts review the current status of boron-containing drugs and materials for molecular medical diagnostics Boron-Based Compounds offers a summary of the present status and promotes the further development of new boron-containing drugs and advanced materials, mostly boron clusters, for molecular medical diagnostics. The knowledge accumulated during the past decades on the chemistry and biology of bioorganic and organometallic boron compounds laid the foundation for the emergence of a new area of study and application of boron compounds as lipophilic pharmacophores and modulators of biologically active molecules.This important text brings together in one comprehensive volume contributions from renowned experts in the field of medicinal chemistry of boron compounds. The authors cover a range of the most relevant topics including boron compounds as modulators of the bioactivity of biomolecules, boron clusters as pharmacophores or for drug delivery, boron compounds for boron neutron capture therapy (BNCT) and for diagnostics, as well as in silico molecular modeling of boron- and carborane-containing compounds in drug design. Authoritative and accessible, Boron-Based Compounds: Contains contributions from a panel of internationally renowned experts in the field Offers a concise summary of the current status of boron-containing drugs and materials used for molecular diagnostics Highlights the range and capacity of boron-based compounds in medical applications Includes information on boron neutron capture therapy and diagnostics Designed for academic and industrial scientists, this important resource offers the cutting-edge information needed to understand the current state of boron-containing drugs and materials for molecular medical diagnostics.

Bone Marrow MRI

Bone Marrow MRI PDF

Author: Lia Angela Moulopoulos

Publisher: Springer

Published: 2014-11-17

Total Pages: 183

ISBN-13: 8847053161

DOWNLOAD EBOOK →

MRI provides the best means of imaging the bone marrow directly and of non-invasively assessing its composition. Normal age-related bone marrow changes, alterations related to red marrow reconversion, and pathological bone marrow processes generally conform to certain patterns that reflect the underlying marrow changes and can be clearly recognized on MR images. In addition to conventional pulse sequences, advanced MRI techniques such as Dynamic Contrast-Enhanced MRI and Diffusion-Weighted Imaging depict marrow changes at the microvascular and cellular level respectively. This book provides radiologists with in-depth information on the MRI appearances of normal, abnormal and treated marrow following a structured, pattern-based approach. MRI findings for various diseases that affect the bone marrow, particularly those of a malignant nature, are presented in detail. MRI pattern recognition not only offers a systematic approach to image interpretation and diagnosis but also has prognostic implications with regard to some disease entities. Each chapter includes a wealth of high-quality images, together with Key Points summarizing the most important information. In addition to radiologists, practitioners with an interest in hematology and oncology will find this textbook-atlas to be a valuable resource for the latest, clinically relevant advances in bone marrow imaging.

Multiple Myeloma

Multiple Myeloma PDF

Author: Thomas Moehler

Publisher: Springer Science & Business Media

Published: 2011-04-21

Total Pages: 349

ISBN-13: 3540857729

DOWNLOAD EBOOK →

Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.

Diffusion-Weighted MR Imaging

Diffusion-Weighted MR Imaging PDF

Author: Dow-Mu Koh

Publisher: Springer

Published: 2012-05-04

Total Pages: 0

ISBN-13: 9783642261442

DOWNLOAD EBOOK →

It is a great privilege to introduce this book devoted to the current and future roles in research and clinical practice of another exciting new development in MRI: Diffusi- weighted MR imaging. This new, quick and non-invasive technique, which requires no contrast media or i- izing radiation, offers great potential for the detection and characterization of disease in the body as well as for the assessment of tumour response to therapy. Indeed, whereas DW-MRI is already ? rmly established for the study of the brain, progress in MR techn- ogy has only recently enabled its successful application in the body. Although the main focus of this book is on the role of DW-MRI in patients with malignant tumours, n- oncological emerging applications in other conditions are also discussed. The editors of this volume, Dr. D. M. Koh and Prof. H. Thoeny, are internationally well known for their pioneering work in the ? eld and their original contributions to the l- erature on DW-MRI of the body. I am very much indebted to them for the enthusiasm and engagement with which they prepared and edited this splendid volume in a record short time for our series Medical Radiology – Diagnostic section.