Molecular Genetics Pt 2

Molecular Genetics Pt 2 PDF

Author: Herbert Taylor

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 534

ISBN-13: 0323146848

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Molecular Genetics, Part II covers the significant developments in various areas of molecular genetics. This book is composed of 10 chapters that also consider the gene expression and regulation of some enzymes. The opening chapters deal with the mechanisms of nucleic acid replication and repair, as well as the structural aspects of the genetic apparatus of viruses and cells. The next chapters explore the patterns and mechanisms of genetic recombination, the in vitro and in vivo experiments to delineate the genetic code, and the initiation of peptide chains in Escherichia coli. These topics are followed by discussions of the mechanism of DNA-dependent RNA synthesis, the regulation of enzyme synthesis in microorganisms, and the regulation of viral replication. The final chapters consider the theoretical and practical aspects of the metabolic regulation in metazoan system and the procedures for the study of DNA-DNA and DNA-RNA interactions. This book will be of great value to molecular geneticists, biochemists, and researchers.

Molecular Genetics

Molecular Genetics PDF

Author: J. T. Hancock

Publisher: Hodder Arnold

Published: 1999

Total Pages: 204

ISBN-13:

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The Biomedical Sciences Explained Series has been designed specifically to meet the needs of today's undergraduates studying biomedical sciences. Each volume in the series covers a key biomedical science topic, enabling the student to select the volumes required for their chosen topics, and build up their own 'personal textbook' in biomedical sciences. Using the BMS Explained Series students can build up their own 'personal textbook' in biomedical sciences, written specifically for them, rather than buying an 'all singing, all dancing' textbook which is too detailed when only studying a topic for one or two modules. Each volume provides a core of knowledge from which the student can then go on to more advanced study in their chosen subject.

The Evaluation of Forensic DNA Evidence

The Evaluation of Forensic DNA Evidence PDF

Author: National Research Council

Publisher: National Academies Press

Published: 1997-01-12

Total Pages: 271

ISBN-13: 0309121949

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In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.

Molecular Genetic Pathology

Molecular Genetic Pathology PDF

Author: Liang Cheng

Publisher: Springer

Published: 2013-03-05

Total Pages: 1136

ISBN-13: 9781461447993

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Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.

Introduction to Genetics

Introduction to Genetics PDF

Author: Terry Brown

Publisher: Garland Pub

Published: 2012

Total Pages: 530

ISBN-13: 9780815365099

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Genetics today is inexorably focused on DNA. The theme of Introduction to Genetics: A Molecular Approach is therefore the progression from molecules (DNA and genes) to processes (gene expression and DNA replication) to systems (cells, organisms and populations). This progression reflects both the basic logic of life and the way in which modern biological research is structured. The molecular approach is particularly suitable for the large number of students for whom genetics is a part of a broader program in biology, biochemistry, the biomedical sciences, and biotechnology. Introduction to Genetics presents the basic facts and concepts with enough depth of knowledge to stimulate students to move on to more advanced aspects of the subject. The book is divided into three parts. Part 1 examines the function of the gene as a unit of biological information. Part 2 studies the role of the gene as a unit of inheritance. And Part 3 explores some of the areas of research that are responsible for the high profile that genetics has in our modern world, from agriculture and industry to medicine and forensics, and the ethical challenges that genetic knowledge imparts. Introduction to Genetics is available for purchase as an e-book in its entirety or as individual chapters, and as a 1-year or 6-month rental.

Introduction to Genetics: A Molecular Approach

Introduction to Genetics: A Molecular Approach PDF

Author: T A Brown

Publisher: Garland Science

Published: 2012-03-22

Total Pages: 554

ISBN-13: 1136665358

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Genetics today is inexorably focused on DNA. The theme of Introduction to Genetics: A Molecular Approach is therefore the progression from molecules (DNA and genes) to processes (gene expression and DNA replication) to systems (cells, organisms and populations). This progression reflects both the basic logic of life and the way in which modern biol

Genes VII

Genes VII PDF

Author: Benjamin Lewin

Publisher:

Published: 2000

Total Pages: 990

ISBN-13: 9780198792802

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Genes VII, the latest edition of this well-respected and best-selling textbook covers the material that is at the core of current courses in molecular biology, genetics, cell biology, and related disciplines. It gives an integrated and authoritative account of the structure and function of genes and is thoroughally up-to-date with the latest research and thinking in the field. In a change to the approach of all previous editions, which started with a traditional analysis of formal genetics, this seventh edition has been organised to present the subject in the context of the eukaryotic gene as revealed in the last decade, an analysis based directly on the molecular properties of the gene itself. This new approach has made the book more concise, and the smart new design presents the material refreshingly clearly. Contents Part 1 Genes 1 Genes are DNA 2 From genes to genomes 3 How many genes are there? 4 Clusters and repeats Part 2 Proteins 5 Messenger DNA 6 Protein Synthesis 7 Interpreting the genetic code 8 Protein localization Part 3 mRNA 9 Transcription 10 The operon 11 Phage strategies Part 4 DNA 12 The replicon 13 DNA replication 14 Recombination and repair 15 Transposons 16 Retroviruses and retroposons 17 Rearrangement of DNA Part 5 The nucleus 18 Chromosomes 19 Nucleosomes 20 Initiation of transcription 21 Regualtion of transcription 22 Nuclear splicing 23 Catalytic RNA 24 Immune diversity Part 6 Cells 25 Protein trafficking 26 Signal transduction 27 Cell cycle and growth regualtion 28 Oncogenes and cancer 29 Gradients and cascades

Molecular Imaging and Precision Medicine, Part II, An Issue of PET Clinics, E-Book

Molecular Imaging and Precision Medicine, Part II, An Issue of PET Clinics, E-Book PDF

Author: Rathan Subramaniam

Publisher: Elsevier Health Sciences

Published: 2017-09-14

Total Pages:

ISBN-13: 0323546811

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This issue of PET Clinics focuses on Molecular Imaging and Precision Medicine, Part II, and is edited by Dr. Rathan Subramaniam. Articles will include: Precision Medicine in Esophageal Cancer; Precision Medicine and PET/CT in Melanoma; Precision Medicine and PET/CT in Hepatobilliary and Pancreatic Cancer; Precision Medicine and PET/CT in Gastric Cancer; Precision Medicine and PET/CT in Skeletal and Soft Tissue Sarcomas; Precision Medicine and PET/MRI; Precision Medicine and PET/CT in Uterine and Ovarian Cancers; Precision Medicine and PET/CT in Cardiovascular Disorders, and more!