Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research PDF

Author: P. Michael Conn

Publisher: Springer Science & Business Media

Published: 2008-03-07

Total Pages: 756

ISBN-13: 1597452858

DOWNLOAD EBOOK →

The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research PDF

Author: P. Michael Conn

Publisher: Springer Science & Business Media

Published: 2008

Total Pages: 756

ISBN-13: 1588299333

DOWNLOAD EBOOK →

The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.

Three Dimensional Human Organotypic Models for Biomedical Research

Three Dimensional Human Organotypic Models for Biomedical Research PDF

Author: Fabio Bagnoli

Publisher: Springer Nature

Published: 2021-05-20

Total Pages: 265

ISBN-13: 3030624528

DOWNLOAD EBOOK →

This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.

Biomedical Models and Resources

Biomedical Models and Resources PDF

Author: National Research Council

Publisher: National Academies Press

Published: 1998-02-16

Total Pages: 85

ISBN-13: 0309060354

DOWNLOAD EBOOK →

Printbegrænsninger: Der kan printes 10 sider ad gangen og max. 40 sider pr. session.

Animal Models for the Study of Human Disease

Animal Models for the Study of Human Disease PDF

Author: P. Michael Conn

Publisher: Academic Press

Published: 2013-05-29

Total Pages: 1108

ISBN-13: 0124159125

DOWNLOAD EBOOK →

Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease

The Developing Marsupial

The Developing Marsupial PDF

Author: C.H. Tyndale-Biscoe

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 253

ISBN-13: 3642884024

DOWNLOAD EBOOK →

Marsupials are excellent objects for studies on developmental processes in all mammals including humans. Marsupials are very immature at birth and undergo most of their development in a pouch where they can be manipulated in a variety of ways without affecting the mother. Most of these studies are on systems which largely mature before birth in eutherian mammals and are consequently difficult to investigate. Attention is also drawn to certain features peculiar to adult marsupials: e.g., they continue to grow throughout adult life, valuable for studies on growth mechanisms, and furthermore the composition of marsupial milk changes radically through lactation, most important in studies of hormonal regulation of milk composition and secretion.

Statistical Modeling in Biomedical Research

Statistical Modeling in Biomedical Research PDF

Author: Yichuan Zhao

Publisher: Springer Nature

Published: 2020-03-19

Total Pages: 495

ISBN-13: 3030334163

DOWNLOAD EBOOK →

This edited collection discusses the emerging topics in statistical modeling for biomedical research. Leading experts in the frontiers of biostatistics and biomedical research discuss the statistical procedures, useful methods, and their novel applications in biostatistics research. Interdisciplinary in scope, the volume as a whole reflects the latest advances in statistical modeling in biomedical research, identifies impactful new directions, and seeks to drive the field forward. It also fosters the interaction of scholars in the arena, offering great opportunities to stimulate further collaborations. This book will appeal to industry data scientists and statisticians, researchers, and graduate students in biostatistics and biomedical science. It covers topics in: Next generation sequence data analysis Deep learning, precision medicine, and their applications Large scale data analysis and its applications Biomedical research and modeling Survival analysis with complex data structure and its applications.

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research PDF

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2019-08-26

Total Pages: 123

ISBN-13: 0309488516

DOWNLOAD EBOOK →

The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.