Methods in Insect Sensory Neuroscience

Methods in Insect Sensory Neuroscience PDF

Author: Thomas A. Christensen

Publisher: CRC Press

Published: 2004-12-20

Total Pages: 461

ISBN-13: 1420039423

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Insects are among the most diverse and adaptable organisms on Earth. They have long been our chief competitors for food and are responsible for spreading devastating afflictions such as malaria and encephalitis. The insects' ability to thrive is due in large part to their well-developed sensory systems, which present a host of novel physiological,

Methods for Neural Ensemble Recordings

Methods for Neural Ensemble Recordings PDF

Author: Miguel A. L. Nicolelis

Publisher: CRC Press

Published: 2007-12-03

Total Pages: 308

ISBN-13: 142000641X

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Extensively updated and expanded, this second edition of a bestseller distills the current state-of-the-science and provides the nuts and bolts foundation of the methods involved in this rapidly growing science. With contributions from pioneering researchers, it includes microwire array design for chronic neural recordings, new surgical techniques for chronic implantation, microelectrode microstimulation of brain tissue, multielectrode recordings in the somatosensory system and during learning, as well as recordings from the central gustatory-reward pathways. It explores the use of Brain-Machine Interface to restore neurological function and proposes conceptual and technical approaches to human neural ensemble recordings in the future.

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades PDF

Author: Wolfgang B. Liedtke, MD, PH.D.

Publisher: CRC Press

Published: 2006-09-29

Total Pages: 502

ISBN-13: 1420005847

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Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Brain Aging

Brain Aging PDF

Author: David R. Riddle

Publisher: CRC Press

Published: 2007-04-19

Total Pages: 335

ISBN-13: 1000611558

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Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Statistical Techniques for Neuroscientists

Statistical Techniques for Neuroscientists PDF

Author: Young K. Truong

Publisher: CRC Press

Published: 2016-10-04

Total Pages: 446

ISBN-13: 1466566159

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Statistical Techniques for Neuroscientists introduces new and useful methods for data analysis involving simultaneous recording of neuron or large cluster (brain region) neuron activity. The statistical estimation and tests of hypotheses are based on the likelihood principle derived from stationary point processes and time series. Algorithms and software development are given in each chapter to reproduce the computer simulated results described therein. The book examines current statistical methods for solving emerging problems in neuroscience. These methods have been applied to data involving multichannel neural spike train, spike sorting, blind source separation, functional and effective neural connectivity, spatiotemporal modeling, and multimodal neuroimaging techniques. The author provides an overview of various methods being applied to specific research areas of neuroscience, emphasizing statistical principles and their software. The book includes examples and experimental data so that readers can understand the principles and master the methods. The first part of the book deals with the traditional multivariate time series analysis applied to the context of multichannel spike trains and fMRI using respectively the probability structures or likelihood associated with time-to-fire and discrete Fourier transforms (DFT) of point processes. The second part introduces a relatively new form of statistical spatiotemporal modeling for fMRI and EEG data analysis. In addition to neural scientists and statisticians, anyone wishing to employ intense computing methods to extract important features and information directly from data rather than relying heavily on models built on leading cases such as linear regression or Gaussian processes will find this book extremely helpful.

Neurobiology of TRP Channels

Neurobiology of TRP Channels PDF

Author: Tamara Luti Rosenbaum Emir

Publisher: CRC Press

Published: 2017-08-09

Total Pages: 327

ISBN-13: 1498755267

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During the last two decades, there has been an explosion of research pertaining to the molecular mechanisms that allow for organisms to detect different stimuli that is an essential feature for their survival. Among these mechanisms, living beings need to be able to respond to different temperatures as well as chemical and physical stimuli. Thermally activated ion channels were proposed to be present in sensory neurons in the 1980s, but it was not until 1997 that a heat- and capsaicin- activated ion channel, TRPV1, was cloned and its function described in detail. This groundbreaking discovery led to the identification and characterization of several more proteins of the family of Transient Receptor Potential (TRP) ion channels. Intensive research has provided us with the atomic structures of some of these proteins, as well as understanding of their physiological roles, both in normal and pathological conditions. With chapters contributed by renowned experts in the field, Neurobiology of TRP Channels contains a state- of- the- art overview of our knowledge of TRP channels, ranging from structure to their functions in organismal physiology. Features: • Contains chapters on the roles of several TRP ion channels with a diversity of physiological functions, providing a complete picture of the widespread importance of these proteins. • Presents an overview of the structure of TRP channels, including the roles of these proteins in different physiological processes. • Discusses the roles of TRP channels in pathophysiological processes, further highlighting their importance. • Features several full color illustrations to allow the reader better comprehension of TRP channels. A volume in the Frontiers in Neuroscience series

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury PDF

Author: Daniel Laskowitz

Publisher: CRC Press

Published: 2016-04-21

Total Pages: 412

ISBN-13: 1466584920

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Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Spatial Temporal Patterns for Action-Oriented Perception in Roving Robots

Spatial Temporal Patterns for Action-Oriented Perception in Roving Robots PDF

Author: Paolo Arena

Publisher: Springer Science & Business Media

Published: 2008-12-19

Total Pages: 438

ISBN-13: 3540884645

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The basic principles guiding sensing, perception and action in bio systems seem to rely on highly organised spatial-temporal dynamics. In fact, all biological senses, (visual, hearing, tactile, etc.) process signals coming from different parts distributed in space and also show a complex time evolution. As an example, mammalian retina performs a parallel representation of the visual world embodied into layers, each of which r- resents a particular detail of the scene. These results clearly state that visual perception starts at the level of the retina, and is not related uniquely to the higher brain centres. Although vision remains the most useful sense guiding usual actions, the other senses, ?rst of all hearing but also touch, become essential particularly in cluttered conditions, where visual percepts are somehow obscured by environment conditions. Ef?cient use of hearing can be learnt from acoustic perception in animals/insects, like crickets, that use this ancient sense more than all the others, to perform a vital function, like mating.

Sociobiology of Communication

Sociobiology of Communication PDF

Author: Patrizia d'Ettorre

Publisher: OUP Oxford

Published: 2008-08-21

Total Pages: 322

ISBN-13: 019155085X

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Communication is essential for all forms of social interaction, from parental care to mate choice and cooperation. This is evident for human societies but less obvious for bacterial biofilms, ant colonies or flocks of birds. The major disciplines of communication research have tried to identify common core principles, but syntheses have been few because historical barriers have limited interaction between different research fields. Sociobiology of Communication is a timely and novel synthesis. It bridges many of the gaps between proximate and ultimate levels of analysis, between empirical model systems, and between biology and the humanities. The book offers the complementary approaches of a distinguished group of authors spanning a large diversity of research programs, addressing, for example, the genetic basis of bacterial communication, dishonest communication in insect societies, sexual selection and network communication among colonial vertebrates. Other chapters explore the role of communication in genomic conflict and self-organisation, and how linguistics, psychology and philosophy may ultimately contribute to a biological understanding of human mate choice and the evolution of human societies. This highly interdisciplinary book highlights key examples of modern research to explore the genetic, neurobiological, physiological, chemical and behavioural basis of social communication. It identifies where consensus on the general principles is emerging and where the major future challenges are to be found. The book is therefore suitable for both for graduate students and professionals in evolutionary biology and behavioural ecology seeking novel inspiration, and for a wider academic audience, including social and medical scientists who would like to explore what evolutionary approaches can offer to their fields.

Serotonin Receptors in Neurobiology

Serotonin Receptors in Neurobiology PDF

Author: Amitabha Chattopadhyay

Publisher: CRC Press

Published: 2007-05-17

Total Pages: 230

ISBN-13: 1420005758

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A number of developments spanning a multitude of techniques makes this an exciting time for research in serotonin receptors. A comprehensive review of the subject from a multidisciplinary perspective, Serotonin Receptors in Neurobiology is among the first books to include information on serotonin receptor knockout studies. With contributions from l