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Metabolic Engineering of Plant Secondary Metabolism

Author: R. Verpoorte

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 288

ISBN-13: 9401594236

Plant secondary metabolism is an economically important source of fine chemicals, such as drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such as taste, flavour, smell, colour, or resistance against pests and diseases are also related to secondary metabolites. The genetic modification of plants is feasible nowadays. What does the possibility of engineering plant secondary metabolite pathways mean? In this book, firstly a general introduction is given on plant secondary metabolism, followed by an overview of the possible approaches that could be used to alter secondary metabolite pathways. In a series of chapters from various authorities in the field, an overview is given of the state of the art for important groups of secondary metabolites. No books have been published on this topic so far. This book will thus be a unique source of information for all those involved with plants as chemical factories of fine chemicals and those involved with the quality of food and ornamental plants. It will be useful in teaching graduate courses in the field of metabolic engineering in plants.

Plant Secondary Metabolism Engineering

Author: Arthur Germano Fett-Neto

Publisher: Methods in Molecular Biology

Published: 2010-05-06

Total Pages: 360

ISBN-13:

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This book presents detailed practical information on important methods used in the engineering of plant secondary metabolism pathways and the acquisition of essential knowledge in performing this activity, including important advances and emerging strategies.

Applications of Plant Metabolic Engineering

Author: Robert Verpoorte

Publisher: Springer

Published: 2010-10-19

Total Pages: 0

ISBN-13: 9789048175109

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Written by leading international experts in the field of plant metabolic engineering, this book discusses how the technology can be applied. Applications resulting from metabolic engineering are expected to play a very important role in the future of plant breeding: for example, in the fields of improved resistance or improved traits concerning health promoting constituents, as well as in the production of fine chemicals such as medicines, flavors and fragrances.

Plant Secondary Metabolism Engineering

Author: Arthur Germano Fett-Neto

Publisher: Humana

Published: 2022-05-05

Total Pages: 262

ISBN-13: 9781071621844

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This second edition provides detailed practical information on important methods employed in the engineering of plant secondary metabolism pathways. New and updated chapters guide readers through extraction, quantification, purification, localization, characterization, data mining and processing, biosynthesis modulation, and pathway engineering of representative classes of plant specialized metabolites. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, list of necessary materials and reagents, tips on troubleshooting and known pitfalls, and step-by-step descriptions of readily reproducible protocols. Authoritative and cutting-edge, Plant Secondary Metabolism Engineering: Methods and Protocols, Second Edition aims to be a useful practical guide to help researchers working in this exciting field.

Recent Trends and Techniques in Plant Metabolic Engineering

Author: Sudesh Kumar Yadav

Publisher: Springer

Published: 2018-11-23

Total Pages: 179

ISBN-13: 9811322511

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Remarkable research has yielded whole genome data in plants, resulting in the documentation of an ever-increasing number of genes, without establishing their functions. The huge data resources available at the genome, transcriptome, proteome and metabolome levels are of enormous value in the field of functional genomics. This book provides insights into interpreting the sea of data in order to understand basic and practical aspects of plant metabolic engineering. It discusses in detail ways to tap into this enormous pool of data to increase productivity, and offers information that is both interesting and necessary for exploring the manipulation of metabolic pathways. The interdisciplinary approaches presented here also serve as a source of ideas for practical applications.

Plant-Environment Interaction

Author: Mohamed Mahgoub Azooz

Publisher: John Wiley & Sons

Published: 2015-11-30

Total Pages: 368

ISBN-13: 1119081025

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The increase in global population, urbanization and industrialization is resulting in the conversion of cultivated land into wasteland. Providing food from these limited resources to an ever-increasing population is one of the biggest challenges that present agriculturalists and plant scientists are facing. Environmental stresses make this situation even graver. Plants on which mankind is directly or indirectly dependent exhibit various mechanisms for their survival. Adaptability of the plants to changing environment is a matter of concern for plant biologists trying to reach the goal of food security. Despite the induction of several tolerance mechanisms, sensitive plants often fail to withstand these environmental extremes. Using new technological approaches has become essential and imperative. Plant-Environment Interaction: Responses and Approaches to Mitigate Stress throws light on the changing environment and the sustainability of plants under these conditions. It contains the most up-to-date research and comprehensive detailed discussions in plant physiology, climate change, agronomy and forestry, sometimes from a molecular point of view, to convey in-depth understanding of the effects of environmental stress in plants, their responses to the environment, how to mitigate the negative effects and improve yield under stress. This edited volume is written by expert plant biologists from around the world, providing invaluable knowledge to graduate and undergraduate students in plant biochemistry, food chemistry, plant physiology, molecular biology, plant biotechnology, and environmental sciences. This book updates scientists and researchers with the very latest information and sustainable methods used for stress tolerance, which will also be of considerable interest to plant based companies and institutions concerned with the campaign of food security.

Applications of Plant Metabolic Engineering

Author: R. Verpoorte

Publisher: Springer Science & Business Media

Published: 2007-07-28

Total Pages: 342

ISBN-13: 1402060319

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Metabolic Engineering

Author: Sang Yup Lee

Publisher: John Wiley & Sons

Published: 2021-06-02

Total Pages: 1075

ISBN-13: 352782345X

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Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.

Synthetic Biology and Metabolic Engineering in Plants and Microbes Part A: Metabolism in Microbes

Author:

Publisher: Academic Press

Published: 2016-07-11

Total Pages: 396

ISBN-13: 0128046163

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Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A, the new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Contains two volumes covering research methods in synthetic biology and metabolic engineering in plants and microbes Presents sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways

Transgenesis and Secondary Metabolism

Author: Sumita Jha

Publisher: Springer

Published: 2017-05-16

Total Pages: 0

ISBN-13: 9783319286686

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This handbook provides comprehensive reference information on the efficient production of secondary metabolites from plants by transgenesis and other genetic manipulation strategies. It reviews and summarizes selected important case studies in genetic methods applied to enhance the production of a given metabolite or a group of related or derived compounds. Readers will find reference information on a multitude of techniques and methods, including traditional breeding and screening; over-expression of genes encoding key enzymes; functional genomics approaches; metabolic engineering of the relevant biosynthetic pathways; indirect genetic approaches to improve metabolite production, including Agrobacterium mediated transformations. Furthermore, combinatorial biochemistry approaches to engineer secondary metabolic pathways are summarized, which can offer access to new structures or to the design of novel compounds. Since many commercially valuable substances are still extracted from plants, being largely inaccessible to efficient modern laboratory synthesis methods, this book provides a valuable resource of information for biotechnological approaches that can help to find alternative and more efficient methods for the production of natural secondary metabolites. Thus adjusted production methods, with the help of tailored plant systems, can potentially help to release the stress on plants, which are currently suffering from extensive human harvesting, and to conserve global biodiversity. Readers will find comprehensive reference information on plant genetic manipulation toward more efficient synthesis, accumulation and production of target secondary metabolites. The handbook will appeal to researchers and professionals, but also graduate students and scholars working in the fields of biotechnology, genetic engineering, medicinal plant research, pharmacy, and phytochemistry.