Trafficking Inside Cells

Trafficking Inside Cells PDF

Author: Nava Segev

Publisher: Springer Science & Business Media

Published: 2010-05-30

Total Pages: 459

ISBN-13: 038793877X

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This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

ARF Family GTPases

ARF Family GTPases PDF

Author: Richard A. Kahn

Publisher: Springer Science & Business Media

Published: 2004-02-29

Total Pages: 368

ISBN-13: 1402017197

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For the first time experts in the area of signalling research with a focus on the ARF family have contributed to the production of a title devoted to ARF biology. A comprehensive phylogenetic analysis of the ARF family, tables of the ARF GEFs and ARF GAPs, and more than a dozen chapters describing them in detail are provided. The impact of the ARF proteins on widely diverse aspects of cell biology and cell signalling can be clearly seen from the activities described; including membrane traffic, lipid metabolism, receptor desensitization, mouse development, microtubule dynamics, and bacterial pathogenesis. Anyone interested in understanding the complexities of cell signalling and the integration of signalling networks will benefit from this volume.

Rab GTPases and Membrane Trafficking

Rab GTPases and Membrane Trafficking PDF

Author: Guangpu Li

Publisher: Bentham Science Publishers

Published: 2012-05-21

Total Pages: 180

ISBN-13: 1608053652

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"Ypt/Rab GTPases form the largest branch of the Ras-related small GTPase superfamily and regulate intracellular membrane trafficking in all eukaryotes. Since their discovery over two decades ago, a wealth of information has accumulated about the roles that"

Membrane Trafficking

Membrane Trafficking PDF

Author: Ales Vancura

Publisher: Springer Science & Business Media

Published: 2008-08-28

Total Pages: 430

ISBN-13: 9781588299253

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As membrane trafficking research has expanded over the past thirty years, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells. This book reflects these advances by devoting one section of the book to yeast cells and the other to mammalian cells, with each section providing both classic and cutting-edge techniques to study macromolecular transport across the membranes.

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades PDF

Author: Wolfgang B. Liedtke, MD, PH.D.

Publisher: CRC Press

Published: 2006-09-29

Total Pages: 502

ISBN-13: 1420005847

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Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Trafficking of Intracellular Membranes:

Trafficking of Intracellular Membranes: PDF

Author: Maria C. Pedroso De Lima

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 366

ISBN-13: 3642795471

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This volume contains the lectures presented at the NATO Advanced Study Institute (ASI) on "Trafficking of Intracellular Membranes: From Molecular Sorting to Membrane Fusion", held in Espinho, Portugal, from June 19 to June 30,1994. The objective of this Institute was to survey recent developments and to discuss future directions in the rapidly advancing field of membrane cell biology, with particular emphasis on the dynamical properties and intracellular flow of membranes. A wide range of interrelated topics around the central theme of intracellular trafficking of membranes was covered, including lipid flow, membrane fusion, dynamics of membrane components, protein folding and assembly, vesicular transport in membrane biogenesis, exocytosis and endocytosis. A large variety of experimental techniques and systems, including the application of viruses and model systems, to study these processes was also considered. Membrane cell biology is a broad discipline which encompasses many scientific areas including cell biology, biochemistry, biophysics, virology, immunonology and genetics. Indeed, recent advances in the cell biology of membranes could not have been made without this multidisciplinary approach. Significant progress achieved during the last few years in understanding how newly synthesized lipids and proteins find their way to the cell organelles, how molecular sorting and the continuous flow of membranes allow each cellular membrane to maintain its own distinct molecular composition, and, thereby, the individuality of the various intracellular compartments, was discussed in considerable detail in this Institute.

Cell Movement

Cell Movement PDF

Author: Magdalena Stolarska

Publisher: Springer

Published: 2018-11-22

Total Pages: 301

ISBN-13: 3319968424

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This book contains a collection of original research articles and review articles that describe novel mathematical modeling techniques and the application of those techniques to models of cell motility in a variety of contexts. The aim is to highlight some of the recent mathematical work geared at understanding the coordination of intracellular processes involved in the movement of cells. This collection will benefit researchers interested in cell motility as well graduate students taking a topics course in this area.

Endocytosis and Signaling

Endocytosis and Signaling PDF

Author: Christophe Lamaze

Publisher: Springer

Published: 2018-08-10

Total Pages: 329

ISBN-13: 3319967045

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This book focuses on the context dependency of cell signaling by showing how the endosomal system helps to structure and regulate signaling pathways. The location and concentration of signaling nodes regulate their activation cycles and engagement with distinct effector pathways. Whilst many cell signaling pathways are initiated from the cell surface, endocytosis provides an opportunity for modulating signaling networks’ output. In this book, first a series of reviews describe the endocytic and endosomal system and show how these subcellular platforms sort and regulate a wide range of signaling pathway components and phenotypic outputs. The book then reviews the latest scientific insights into how endocytic trafficking and subcellular location modulate a set of major pathways that are essential to normal cellular function and organisms’ development.