Medical Genetics of Endometrial Cancer
Author: Garden Grove Garden Grove Press
Publisher:
Published: 2017-03-25
Total Pages: 168
ISBN-13: 9781544932149
DOWNLOAD EBOOK →This article collection reviews the medical genetics of endometrial cancer and includes 20 papers by various authors. Topics include: Genetic variants in MUTYH are not associated with endometrial cancer risk; Lynch syndrome related endometrial cancer: clinical significance beyond the endometrium; Management of ovarian and endometrial cancers in women belonging to HNPCC carrier families: review of the literature and results of cancer risk assessment in Polish HNPCC families; Genetic testing in a gynaecological oncology care in developing countries - knowledge, attitudes and perception of Nepalese clinicians; New classification of endometrial cancers: the development and potential applications of genomic-based classification in research and clinical care; PIpelle Prospective ENDOmetrial carcinoma (PIPENDO) study, pre-operative recognition of high risk endometrial carcinoma: a multicentre prospective cohort study; Toll-Like Receptor (TLR) and Nucleosome-binding Oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk; Genetic variations of MUC17 are associated with endometriosis development and related infertility; Multiplex genetic cancer testing identifies pathogenic mutations in TP53 and CDH1 in a patient with bilateral breast and endometrial adenocarcinoma; Two novel sequence variants in MSH2 gene in a patient who underwent cancer genetic counseling for a very early-onset epithelial ovarian cancer; Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach; Potential contribution of the uterine microbiome in the development of endometrial cancer; The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor; Common mitochondrial polymorphisms as risk factor for endometrial cancer; Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma; Immunotherapy in endometrial cancer - an evolving therapeutic paradigm; HNF1B polymorphism influences the prognosis of endometrial cancer patients: a cohort study; Molecular characteristics of endometrial cancer coexisting with peritoneal malignant mesothelioma in Li-Fraumeni-like syndrome; Tracking the origin of simultaneous endometrial and ovarian cancer by next-generation sequencing - a case report; The impact of microRNA-mediated PI3K/AKT signaling on epithelial-mesenchymal transition and cancer stemness in endometrial cancer. Proceeds from the sale of this book go to the support of an elderly disabled person.