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Mechanisms of Memory

Author: J. David Sweatt

Publisher: Academic Press

Published: 2009-09-28

Total Pages: 362

ISBN-13: 0080959199

This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding. More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples

Mechanisms of Memory

Author: J. David Sweatt

Publisher: Elsevier

Published: 2003-11-18

Total Pages: 350

ISBN-13: 9780080521961

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This book stands as the first unified overview of the cellular and molecular mechanisms underlying higher-order learning and memory. It integrates modern discoveries concerning learning and memory disorders such as mental retardation syndromes and Alzheimer's Disease, while also emphasizing the results gained from the cutting-edge research methodologies of genetic engineering, complex behavioral characterization, proteomics, and molecular biology. This book provides a foundation of experimental design that will be useful to all students pursuing an interest in laboratory research. This book is an enlightening and invaluable resource for anyone concerned with memory mechanisms. * Presents a unified view of memory mechanisms from behavior to genes and drawing examples from many different brain regions, types of learning, and various animal model systems * Includes numerous practical examples for the new investigator on how to implement research program in the area of learning and memory * Provides a balanced treatment of the strengths and weaknesses in modern experimental design

Mechanisms of Memory

Author: J. David Sweatt

Publisher: Academic Press

Published: 2010

Total Pages: 343

ISBN-13: 9780123749512

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'Sweatt has done a superb and scholarly job of telling the story of this field.' - Howard Eichenbaum, Editor in Chief Hippocampus, Boston University 'It is definitely worth publishing a second edition. David is a leader in the field. the book is well written and has lots of nice figures making it easy to teach from.' - Daniel Johnston, Director, Center for Learning and Memory; Director, Institute for Neuroscience, University of Texas at Austin Sweatt is an outstanding writer and conveyer of complex concepts. He engages readers with lots of examples and detailed explanations for the most diffic

Neuronal Mechanisms of Memory Formation

Author: Christian Hölscher

Publisher: Cambridge University Press

Published: 2001

Total Pages: 509

ISBN-13: 052177067X

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Long-term potentiation (LTP) is by far the most dominant model for neuronal changes that might encode memory. LTP is an elegant concept that meets many criteria set up by theoreticians long before the model's discovery, and it also fits anatomical data of learning-dependent synapse changes. Since the discovery of LTP, the question has remained about how closely LTP produced in vitro by artificial stimulation of neurons actually models putative learning-induced synaptic changes. A number of recent investigations have tried to correlate synaptic changes observed after learning with changes produced by artificial stimulation of neurons. These studies have failed to find a correlation between the two forms of synaptic plasticity. In this book, an international group of neurobiologists and psychologists discuss their latest ideas and data. The results of experiments using electrophysiological techniques in vitro are discussed and compared with the results of in vivo experiments. Learning experiments are also discussed. Theoretical models such as the Hebb theory of synaptic changes during learning are compared to different models that do not predict upregulation of synaptic transmission. A wide approach is taken, and research and models in different brain areas such as the neocortex and the basal brain are discussed.

Neural Plasticity and Memory

Author: Federico Bermudez-Rattoni

Publisher: CRC Press

Published: 2007-04-17

Total Pages: 368

ISBN-13: 1420008412

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A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

Memory Mechanisms in Health and Disease

Author: Karl Peter Giese

Publisher: World Scientific

Published: 2012-06-07

Total Pages: 460

ISBN-13: 9814458147

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Memory Mechanisms is an edited review volume that summarizes state-of-the-art knowledge on memory mechanisms at the molecular, cellular and circuit level. Each review is written by leading experts in the field, presenting not only current knowledge, but also discussing the concepts, providing critical reflections and suggesting an outlook for future studies. The memory mechanisms are also discussed in the context of diseases. Studies of memory deficits in disease models are introduced as well as approaches to restore memory deficits. Finally, the impact of contemporary memory research for psychiatry is illustrated. Contents:Introduction (Karl Peter Giese)Long-term Potentiation and Memory (Karl Peter Giese)Structural Synaptic and Dendritic Spine Plasticity in the Hippocampus (Michael G Stewart and Victor I Popov)Memory Beyond Synaptic Plasticity: The Role of Intrinsic Neuronal Excitability (Athanasia Papoutsi, Kyriaki Sidiropoulou and Panayiota Poirazi)Adult Hippocampal Neurogenesis and Memory (Scellig S D Stone and Paul W Frankland)Memory Consolidation and Its Underlying Mechanisms (Cristina M Alberini, Dhananjay Bambah-Mukku and Dillon Y Chen)The Role of CREB and CREB Co-activators in Memory Formation (Melanie J Sekeres, Derya Sargin, P Joel Ross and Sheena A Josselyn)Sex Differences in Memory Formation (Keiko Mizuno and Karl Peter Giese)Neocortical Learning, Memory and Experience-dependent Plasticity (Giorgia Albieri and Gerald T Finnerty)Mechanisms of Memory Storage (Kimberly Lackenby and Karl Peter Giese)Memory Reconsolidation and Extinction (Satoshi Kida)Memory Circuits in Drosophila (Katsuo Furukubo-Tokunaga, Zoe N Ludlow and Frank Hirth)Memory Circuits in the Hippocampus (Thomas J McHugh)Impaired Memory Mechanisms in Mouse Models of Alzheimer's Disease (Masuo Ohno)Restoring Memory Deficits in Cognitive Diseases (Andre Fischer)The Impact of Studies of Memory Mechanisms for Psychiatry (Shahid H Zaman) Readership: Students and professionals interested in neurology/neuroscience. Keywords:Brain;Learning;Mental Health;Memory;Neuronal Networks;Plasticity;SignallingKey Features:The book provides a comprehensive overview on mechanisms of memoryThe book is useful for organizing undergraduate courses and for the teaching of medical studentsIt complements more basic text books such as “Mechanisms of Memory” by JD Sweatt, Academic Press, 2009, and it provides insights into memory dysfunction in diseases and routes for treating such deficits

Discovering the Brain

Author: National Academy of Sciences

Publisher: National Academies Press

Published: 1992-01-01

Total Pages: 195

ISBN-13: 0309045290

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The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Evolution of Learning and Memory Mechanisms

Author: Mark A. Krause

Publisher: Cambridge University Press

Published: 2022-05-19

Total Pages: 521

ISBN-13: 1108487998

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This book examines how evolution influences learning and memory processes in both human and nonhuman animals.

Cognitive Neuroscience of Memory Consolidation

Author: Nikolai Axmacher

Publisher: Springer

Published: 2017-02-09

Total Pages: 417

ISBN-13: 3319450662

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This edited volume provides an overview the state-of-the-art in the field of cognitive neuroscience of memory consolidation. In a number of sections, the editors collect contributions of leading researchers . The topical focus lies on current issues of interest such as memory consolidation including working and long-term memory. In particular, the role of sleep in relation to memory consolidation will be addressed. The target audience primarily comprises research experts in the field of cognitive neuroscience but the book may also be beneficial for graduate students.

Mechanisms of Sensory Working Memory

Author: Pierre Jolicoeur

Publisher: Elsevier

Published: 2016-06-17

Total Pages: 312

ISBN-13: 0128110430

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Mechanisms of Sensory Working Memory: Attention and Performance XXV provides an update on research surrounding the memory processes that are crucial for many facets of cognitive processing and experience, with new coverage of emerging areas of study, including a new understanding of working memory for features of stimuli devoid of verbal, phonological, or long-term memory content, such as memory for simple visual features (e.g., texture or color), simple auditory features (e.g., pitch), or simple tactile features (e.g., vibration frequency), now called sensory memory to distinguish from verbal memory. This contemporary focus on sensory memory is just beginning, and this collection of original contributions provides a foundational reference for the study mechanisms of sensory memory. Students, scholars, and researchers studying memory mechanisms and processes in cognitive neuroscience, cognitive science, neuroscience, and psychology will find this book of great value to their work. Introduces the study of sensory mechanisms of working memory as distinct from verbal memory Covers visual memory, auditory memory, and tactile memory Includes translational content as the breakdown of working memory is often associated with a disease, disorder, or trauma to the brain