Mathematical Modeling and Simulation in Enteric Neurobiology

Mathematical Modeling and Simulation in Enteric Neurobiology PDF

Author: Roustem Miftahof

Publisher: World Scientific

Published: 2009

Total Pages: 350

ISBN-13: 981283480X

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The lack of scientists equally trained and prepared to understand both mathematics and biology/medicine hampers the development and application of computer simulation methods in biology and neurogastrobiology. Currently, there are no texts for navigating the extensive and intricate field of mathematical and computational modeling in neurogastrobiology. This book bridges the gap between mathematicians, computer scientists and biologists, and thus assists in the study and analysis of complex biological phenomena that cannot be done through traditional in vivo and in vitro experimental approaches.The book recognizes the complexity of biological phenomena under investigation and treats the subject matter with a degree of mathematical rigor. Special attention is given to computer simulations for interpolation and extrapolation of electromechanical and chemoelectrical phenomena, nonlinear self-sustained electromechanical wave activity, pharmacological effects including co-localization and co-transmission by multiple neurotransmitters, receptor polymodality, and drug interactions.Mathematical Modeling and Simulation in Enteric Neurobiology is an interdisciplinary book and is an essential source of information for biologists and doctors who are interested in knowing about the role and advantages of numerical experimentation in their subjects, as well as for mathematicians who are interested in exploring new areas of applications.

Mathematical Foundations and Biomechanics of the Digestive System

Mathematical Foundations and Biomechanics of the Digestive System PDF

Author: Roustem N. Miftahof

Publisher: Cambridge University Press

Published: 2010-05-06

Total Pages: 241

ISBN-13: 1139485776

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Mathematical modelling of physiological systems promises to advance our understanding of complex biological phenomena and pathophysiology of diseases. In this book, the authors adopt a mathematical approach to characterize and explain the functioning of the gastrointestinal system. Using the mathematical foundations of thin shell theory, the authors patiently and comprehensively guide the reader through the fundamental theoretical concepts, via step-by-step derivations and mathematical exercises, from basic theory to complex physiological models. Applications to nonlinear problems related to the biomechanics of abdominal viscera and the theoretical limitations are discussed. Special attention is given to questions of complex geometry of organs, effects of boundary conditions on pellet propulsion, as well as to clinical conditions, e.g. functional dyspepsia, intestinal dysrhythmias and the effect of drugs to treat motility disorders. With end of chapter problems, this book is ideal for bioengineers and applied mathematicians.

Modelling in Medicine and Biology

Modelling in Medicine and Biology PDF

Author: C. A. Brebbia

Publisher: WIT Press

Published: 2011

Total Pages: 221

ISBN-13: 1845645723

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The idea of preparing this volume originated from the ever increasing importance of computational modelling of complex problems in medicine. Considerable advances have been made in this area as demonstrated by the continued success of the International Conference on Modelling in Medicine and Biology organised by the Wessex Institute of Technology.The work reported at those meetings and the research carried out at the Wessex Institute of Technology indicated the increasing interaction and collaboration between medical and engineering scientists. Advances presented at these conferences are now being used in practice for a wide range of medical and surgical applications.The considerable improvements and evolution of the field has led to some of the best scientists, who have participated in our conferences, to write an article on their most recent research. This has led to thirteen outstanding articles published in this volume which encompass important areas of biomedical modelling.

Modelling in Medicine and Biology VIII

Modelling in Medicine and Biology VIII PDF

Author: C. A. Brebbia

Publisher: WIT Press

Published: 2009

Total Pages: 353

ISBN-13: 1845641833

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Featuring contributions from the eighth International Conference on Modelling in Medicine and Biology, this volume covers a broad spectrum of topics including the application of computers to simulate biomedical phenomena. It will be of interest to medical and physical scientists and engineers.

Modelling in Medicine and Biology X

Modelling in Medicine and Biology X PDF

Author: R. Kiss

Publisher: WIT Press

Published: 2013-04-01

Total Pages: 301

ISBN-13: 1845647076

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This book contains contributions from the tenth International Conference on Modelling in Medicine and Biology. The advances covered in the computer modelling, and computational methods and measurements, and their integration, have applications in the study of orthopaedics, cardiovascular systems biomechanics and electrical simulation, amongst others, and are leading to progress in medical care and treatment.

Mathematical and Theoretical Neuroscience

Mathematical and Theoretical Neuroscience PDF

Author: Giovanni Naldi

Publisher: Springer

Published: 2018-03-20

Total Pages: 253

ISBN-13: 3319682970

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This volume gathers contributions from theoretical, experimental and computational researchers who are working on various topics in theoretical/computational/mathematical neuroscience. The focus is on mathematical modeling, analytical and numerical topics, and statistical analysis in neuroscience with applications. The following subjects are considered: mathematical modelling in Neuroscience, analytical and numerical topics; statistical analysis in Neuroscience; Neural Networks; Theoretical Neuroscience. The book is addressed to researchers involved in mathematical models applied to neuroscience.

Computational Neuroscience

Computational Neuroscience PDF

Author: Erik De Schutter

Publisher: CRC Press

Published: 2000-11-22

Total Pages: 368

ISBN-13: 1420039296

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Designed primarily as an introduction to realistic modeling methods, Computational Neuroscience: Realistic Modeling for Experimentalists focuses on methodological approaches, selecting appropriate methods, and identifying potential pitfalls. The author addresses varying levels of complexity, from molecular interactions within single neurons to the

Introduction to Mathematical Biology

Introduction to Mathematical Biology PDF

Author: Ching Shan Chou

Publisher: Springer

Published: 2016-04-27

Total Pages: 172

ISBN-13: 3319296388

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This book is based on a one semester course that the authors have been teaching for several years, and includes two sets of case studies. The first includes chemostat models, predator-prey interaction, competition among species, the spread of infectious diseases, and oscillations arising from bifurcations. In developing these topics, readers will also be introduced to the basic theory of ordinary differential equations, and how to work with MATLAB without having any prior programming experience. The second set of case studies were adapted from recent and current research papers to the level of the students. Topics have been selected based on public health interest. This includes the risk of atherosclerosis associated with high cholesterol levels, cancer and immune interactions, cancer therapy, and tuberculosis. Readers will experience how mathematical models and their numerical simulations can provide explanations that guide biological and biomedical research. Considered to be the undergraduate companion to the more advanced book "Mathematical Modeling of Biological Processes" (A. Friedman, C.-Y. Kao, Springer – 2014), this book is geared towards undergraduate students with little background in mathematics and no biological background.

Cellular Biophysics and Modeling

Cellular Biophysics and Modeling PDF

Author: Greg Conradi Smith

Publisher: Cambridge University Press

Published: 2019-03-14

Total Pages: 395

ISBN-13: 1108686613

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What every neuroscientist should know about the mathematical modeling of excitable cells. Combining empirical physiology and nonlinear dynamics, this text provides an introduction to the simulation and modeling of dynamic phenomena in cell biology and neuroscience. It introduces mathematical modeling techniques alongside cellular electrophysiology. Topics include membrane transport and diffusion, the biophysics of excitable membranes, the gating of voltage and ligand-gated ion channels, intracellular calcium signalling, and electrical bursting in neurons and other excitable cell types. It introduces mathematical modeling techniques such as ordinary differential equations, phase plane, and bifurcation analysis of single-compartment neuron models. With analytical and computational problem sets, this book is suitable for life sciences majors, in biology to neuroscience, with one year of calculus, as well as graduate students looking for a primer on membrane excitability and calcium signalling.