Mathematical Grammar of Biology

Mathematical Grammar of Biology PDF

Author: Michel Eduardo Beleza Yamagishi

Publisher: Springer

Published: 2017-08-31

Total Pages: 82

ISBN-13: 3319626892

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This seminal, multidisciplinary book shows how mathematics can be used to study the first principles of DNA. Most importantly, it enriches the so-called “Chargaff’s grammar of biology” by providing the conceptual theoretical framework necessary to generalize Chargaff’s rules. Starting with a simple example of DNA mathematical modeling where human nucleotide frequencies are associated to the Fibonacci sequence and the Golden Ratio through an optimization problem, its breakthrough is showing that the reverse, complement and reverse-complement operators defined over oligonucleotides induce a natural set partition of DNA words of fixed-size. These equivalence classes, when organized into a matrix form, reveal hidden patterns within the DNA sequence of every living organism. Intended for undergraduate and graduate students both in mathematics and in life sciences, it is also a valuable resource for researchers interested in studying invariant genomic properties.

An Introduction to the Mathematics of Biology: with Computer Algebra Models

An Introduction to the Mathematics of Biology: with Computer Algebra Models PDF

Author: Edward K. Yeargers

Publisher: Springer Science & Business Media

Published: 2013-12-01

Total Pages: 426

ISBN-13: 147571095X

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Biology is a source of fascination for most scientists, whether their training is in the life sciences or not. In particular, there is a special satisfaction in discovering an understanding of biology in the context of another science like mathematics. Fortunately there are plenty of interesting (and fun) problems in biology, and virtually all scientific disciplines have become the richer for it. For example, two major journals, Mathematical Biosciences and Journal of Mathematical Biology, have tripled in size since their inceptions 20-25 years ago. The various sciences have a great deal to give to one another, but there are still too many fences separating them. In writing this book we have adopted the philosophy that mathematical biology is not merely the intrusion of one science into another, but has a unity of its own, in which both the biology and the math ematics should be equal and complete, and should flow smoothly into and out of one another. We have taught mathematical biology with this philosophy in mind and have seen profound changes in the outlooks of our science and engineering students: The attitude of "Oh no, another pendulum on a spring problem!," or "Yet one more LCD circuit!" completely disappeared in the face of applications of mathematics in biology. There is a timeliness in calculating a protocol for ad ministering a drug.

Mathematical Models in Biology

Mathematical Models in Biology PDF

Author: Elizabeth Spencer Allman

Publisher: Cambridge University Press

Published: 2004

Total Pages: 388

ISBN-13: 9780521525862

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This introductory textbook on mathematical biology focuses on discrete models across a variety of biological subdisciplines. Biological topics treated include linear and non-linear models of populations, Markov models of molecular evolution, phylogenetic tree construction, genetics, and infectious disease models. The coverage of models of molecular evolution and phylogenetic tree construction from DNA sequence data is unique among books at this level. Computer investigations with MATLAB are incorporated throughout, in both exercises and more extensive projects, to give readers hands-on experience with the mathematical models developed. MATLAB programs accompany the text. Mathematical tools, such as matrix algebra, eigenvector analysis, and basic probability, are motivated by biological models and given self-contained developments, so that mathematical prerequisites are minimal.

A Course in Mathematical Biology

A Course in Mathematical Biology PDF

Author: Gerda de Vries

Publisher: SIAM

Published: 2006-07-01

Total Pages: 307

ISBN-13: 0898716128

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This is the only book that teaches all aspects of modern mathematical modeling and that is specifically designed to introduce undergraduate students to problem solving in the context of biology. Included is an integrated package of theoretical modeling and analysis tools, computational modeling techniques, and parameter estimation and model validation methods, with a focus on integrating analytical and computational tools in the modeling of biological processes. Divided into three parts, it covers basic analytical modeling techniques; introduces computational tools used in the modeling of biological problems; and includes various problems from epidemiology, ecology, and physiology. All chapters include realistic biological examples, including many exercises related to biological questions. In addition, 25 open-ended research projects are provided, suitable for students. An accompanying Web site contains solutions and a tutorial for the implementation of the computational modeling techniques. Calculations can be done in modern computing languages such as Maple, Mathematica, and MATLAB?.

Mathematical Modeling in Biology

Mathematical Modeling in Biology PDF

Author: Shandelle M. Henson

Publisher: CRC Press

Published: 2022-12-29

Total Pages: 285

ISBN-13: 1000806103

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Mathematical Modeling in Biology: A Research Methods Approach is a textbook written primarily for advanced mathematics and science undergraduate students and graduate-level biology students. Although the applications center on ecology, the expertise of the authors, the methodology can be imported to any other science, including social science and economics. The aim of the book, beyond being a useful aid to teaching and learning the core modeling skills needed for mathematical biology, is to encourage students to think deeply and clearly about the meaning of mathematics in science and to learn significant research methods. Most importantly, it is hoped that students will experience some of the excitement of doing research. Features Minimal pre-requisites beyond a solid background in calculus, such as a calculus I course. Suitable for upper division mathematics and sciences students and graduate-level biology students. Provides sample MATLAB codes and instruction in Appendices along with datasets available on https://bit.ly/3fcLF3D

Mathematical Biology

Mathematical Biology PDF

Author: James D. Murray

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 783

ISBN-13: 3662085429

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Mathematics has always benefited from its involvement with developing sciences. Each successive interaction revitalises and enhances the field. Biomedical science is clearly the premier science of the foreseeable future. For the continuing health of their subject mathematicians must become involved with biology. With the example of how mathematics has benefited from and influenced physics, it is clear that if mathematicians do not become involved in the biosciences they will simply not be a part of what are likely to be the most important and exciting scientific discoveries of all time. Mathematical biology is a fast growing, well recognised, albeit not clearly defined, subject and is, to my mind, the most exciting modern application of mathematics. The increasing use of mathematics in biology is inevitable as biol ogy becomes more quantitative. The complexity of the biological sciences makes interdisciplinary involvement essential. For the mathematician, biology opens up new and exciting branches while for the biologist mathematical modelling offers another research tool commmensurate with a new powerful laboratory technique but only if used appropriately and its limitations recognised. However, the use of esoteric mathematics arrogantly applied to biological problems by mathemati cians who know little about the real biology, together with unsubstantiated claims as to how important such theories are, does little to promote the interdisciplinary involvement which is so essential. Mathematical biology research, to be useful and interesting, must be relevant biologically.

Mathematical Biology

Mathematical Biology PDF

Author: James D. Murray

Publisher: Springer Science & Business Media

Published: 2007-06-12

Total Pages: 551

ISBN-13: 0387224378

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Mathematical Biology is a richly illustrated textbook in an exciting and fast growing field. Providing an in-depth look at the practical use of math modeling, it features exercises throughout that are drawn from a variety of bioscientific disciplines - population biology, developmental biology, physiology, epidemiology, and evolution, among others. It maintains a consistent level throughout so that graduate students can use it to gain a foothold into this dynamic research area.

Mathematical Biology II

Mathematical Biology II PDF

Author: James D. Murray

Publisher: Springer Science & Business Media

Published: 2011-02-15

Total Pages: 834

ISBN-13: 0387952284

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This richly illustrated third edition provides a thorough training in practical mathematical biology and shows how exciting mathematical challenges can arise from a genuinely interdisciplinary involvement with the biosciences. It has been extensively updated and extended to cover much of the growth of mathematical biology. From the reviews: ""This book, a classical text in mathematical biology, cleverly combines mathematical tools with subject area sciences."--SHORT BOOK REVIEWS

Grammars and Automata for String Processing

Grammars and Automata for String Processing PDF

Author: Carlos Martin-Vide

Publisher: CRC Press

Published: 2004-11-23

Total Pages: 436

ISBN-13: 9780203009642

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The conventional wisdom was that biology influenced mathematics and computer science. But a new approach has taken hold: that of transferring methods and tools from computer science to biology. The reverse trend is evident in Grammars and Automata for String Processing: From Mathematics and Computer Science to Biology and Back. The contributors address the structural (syntactical) view of the domain. Mathematical linguistics and computer science can offer various tools for modeling complex macromolecules and for analyzing and simulating biological issues. This collection is valuable for students and researchers in biology, computer science, and applied mathematics.