-PDF Download- Mass Spectrometry Imaging Of Small Molecules EBOOK

Mass Spectrometry Imaging of Small Molecules

Author: Lin He

Publisher: Humana

Published: 2016-09-22

Total Pages: 0

ISBN-13: 9781493954087

This volume presents new developments in the field of mass spectrometry imaging, covering imaging, software, data analysis, new instrumentations, and new methodological approaches. Chapters provide detailed operational instructions from sample preparation to method selection, from comparative quantification to structural identification and from data collection to visualization of small molecule mapping in complex samples. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mass Spectrometry Imaging of Small Molecules aims to to bring the rapidly maturing methods of metabolic imaging to life science researchers and to minimize technical intimidation in adapting new technological platforms in biological research.

Mass Spectrometry Imaging of Small Molecules

Author: Young-Jin Lee

Publisher: Humana

Published: 2022-12-28

Total Pages: 0

ISBN-13: 9781071620328

DOWNLOAD EBOOK →

This volume presents updated methods and new developments in the field of mass spectrometry imaging. Chapters guide readers through four parts covering imaging, software, data analysis, new instrumentation, and new methodological approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mass Spectrometry Imaging of Small Molecules aims to be a useful practical guide to researchers to help further their study in this field.

MALDI Mass Spectrometry Imaging

Author: Tiffany Siegel Porta

Publisher: Royal Society of Chemistry

Published: 2021-12-03

Total Pages: 541

ISBN-13: 1839162414

DOWNLOAD EBOOK →

This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.

Mass Spectrometry Imaging in Food Analysis

Author: Leo M.L. Nollet

Publisher: CRC Press

Published: 2020-04-29

Total Pages: 215

ISBN-13: 0429765304

DOWNLOAD EBOOK →

Food contains various compounds and many technologies exist to analyze those molecules of interest. However, the analysis of the spatial distribution of those compounds using conventional technology, such as liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry is difficult. Mass spectrometry imaging (MSI) is a mass spectrometry technique to visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses. Despite the fact that MSI has been generally considered a qualitative method, the signal generated by this technique is proportional to the relative abundance of the analyte and so quantification is possible. Mass Spectrometry Imaging in Food Analysis, a volume in the Food Analysis and Properties Series, explains how the novel use of matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) will be an ideal complementary approach. MALDI-MSI is a two-dimensional MALDI-MS technology that can detect compounds in a tissue section without extraction, purification, separation, or labeling. It can be used to visualize the spatial distribution of biomolecules in foods. Features: Explains the novel use of matrix-assisted laser desorption/ionization mass spectrometry imaging in food analysis Describes how MALDI-MSI will be a useful technique for optical quality assurance. Shows how MALDI-MSI detects food contaminants and residues Covers the historical development of the technology While there are a multitude of books on mass spectrometry, none focus on food applications and thus this book is ideally suited to food scientists, food industry personnel engaged in product development, research institutions, and universities active in food analysis or chemical analysis. Also available in the Food Analysis and Properties Series: Food Aroma Evolution: During Food Processing, Cooking, and Aging, edited by Matteo Bordiga and Leo M.L. Nollet (ISBN: 9781138338241) Ambient Mass Spectroscopy Techniques in Food and the Environment, edited by Leo M.L. Nollet and Basil K. Munjanja (ISBN: 9781138505568) Hyperspectral Imaging Analysis and Applications for Food Quality, edited by N.C. Basantia, Leo M.L. Nollet, and Mohammed Kamruzzaman (ISBN: 9781138630796) For a complete list of books in this series, please visit our website at: www.crcpress.com/Food-Analysis--Properties/book-series/CRCFOODANPRO

Principles and Applications of Clinical Mass Spectrometry

Author: Nader Rifai

Publisher: Elsevier

Published: 2018-06-26

Total Pages: 216

ISBN-13: 0128160640

DOWNLOAD EBOOK →

Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field

Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry

Author: Bindesh Shrestha

Publisher: Elsevier

Published: 2021-04-23

Total Pages: 272

ISBN-13: 0128189991

DOWNLOAD EBOOK →

Imaging mass spectrometry (MS) techniques are often utilized without an understanding of their underlying principles, making it difficult for scientists to determine when and how they can exploit MS to visualize their biomolecules of interest. Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry is an essential reference to help scientists determine the status and strategies of biomolecule analysis, describing its many applications for diverse classes of biomolecules. The book builds a foundation of imaging MS knowledge by introducing ionization sources, sample preparation, visualization guidelines, molecule identification, quantification, data analysis, etc. The second section contains chapters focused on case studies on analyzing a biomolecule class of molecules. Case studies include an introduction/background, and a summary of successful imaging MS studies with illustrative figures and future directions. Provides the introductory foundations of imaging mass spectrometry for those new to the technique Organized by topic to facilitate a quick deep dive, allowing researchers to immediately apply the imaging MS techniques to their work Includes case studies summarizing the imaging MS techniques developed for the class of molecules

Mass Spectrometry of Natural Products

Author: B. Sklarz

Publisher: Elsevier

Published: 2013-09-11

Total Pages: 103

ISBN-13: 1483158748

DOWNLOAD EBOOK →

Mass Spectrometry of Natural Products covers the plenary lectures presented at the International Mass Spectrometry Symposium on Natural Products, held in Rehovot, Israel from August 28 to September 2, 1977. The book focuses on the sequencing, spectroscopy, chromatography, and spectrometry of natural products. The selection first discusses mass spectrometric sequencing of peptides and proteins and mass spectroscopic investigation of nucleic acid degradation products. The book then examines advances in the mass spectrometry of steroids, including sterols with unsaturated side chains and ring D fragmentation of saturated sterols and steranes. The text evaluates the mass spectrometry and language of biological fluids. Topics include separation by glass capillary chromatography and structure of determination of unknown compounds. The book also focuses on structural and sequencing studies on peptides, proteins, and glycopeptide by mass spectrometry and directed fragmentation in mass spectrometry by the introduction of functional groups. The selection is a dependable reference for readers interested in mass spectrometry of natural products.

Imaging Mass Spectrometry

Author: Mitsutoshi Setou

Publisher: Springer

Published: 2011-08-27

Total Pages: 272

ISBN-13: 9784431800774

DOWNLOAD EBOOK →

Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening are experiencing greater use of this technology, with a concurrent increase in the number of researchers in academia and industry interested in wider applications of IMS. Intended for beginners or those with limited experience with IMS technology, this book provides practical details and instructions needed for immediate know-how, including the preparation of animal tissue samples, the application of a matrix, instrumental operations, and data analysis, among others. By describing the foundations of IMS, this volume contributes to the ongoing development of the field and to progress in human health.

Proteomics for Biological Discovery

Author: Timothy D. Veenstra

Publisher: John Wiley & Sons

Published: 2006-06-12

Total Pages: 361

ISBN-13: 0470007737

DOWNLOAD EBOOK →

Written by recognized experts in the study of proteins, Proteomics for Biological Discovery begins by discussing the emergence of proteomics from genome sequencing projects and a summary of potential answers to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are then dealt with in terms of underlying concepts, limitations and future directions. An invaluable source of information, this title also provides a thorough overview of the current developments in post-translational modification studies, structural proteomics, biochemical proteomics, microfabrication, applied proteomics, and bioinformatics relevant to proteomics. Presents a comprehensive and coherent review of the major issues faced in terms of technology development, bioinformatics, strategic approaches, and applications Chapters offer a rigorous overview with summary of limitations, emerging approaches, questions, and realistic future industry and basic science applications Discusses higher level integrative aspects, including technical challenges and applications for drug discovery Accessible to the novice while providing experienced investigators essential information Proteomics for Biological Discovery is an essential resource for students, postdoctoral fellows, and researchers across all fields of biomedical research, including biochemistry, protein chemistry, molecular genetics, cell/developmental biology, and bioinformatics.

Imaging Mass Spectrometry

Author: Mitsutoshi Setou

Publisher: Springer Science & Business Media

Published: 2010-01-29

Total Pages: 252

ISBN-13: 4431094253

DOWNLOAD EBOOK →