Logic Synthesis for Genetic Diseases

Logic Synthesis for Genetic Diseases PDF

Author: Pey-Chang Kent Lin

Publisher: Springer Science & Business Media

Published: 2013-10-31

Total Pages: 112

ISBN-13: 146149429X

DOWNLOAD EBOOK →

This book brings to bear a body of logic synthesis techniques, in order to contribute to the analysis and control of Boolean Networks (BN) for modeling genetic diseases such as cancer. The authors provide several VLSI logic techniques to model the genetic disease behavior as a BN, with powerful implicit enumeration techniques. Coverage also includes techniques from VLSI testing to control a faulty BN, transforming its behavior to a healthy BN, potentially aiding in efforts to find the best candidates for treatment of genetic diseases.

Genetic Medicine

Genetic Medicine PDF

Author: Barton Childs

Publisher: JHU Press

Published: 1999-08-03

Total Pages: 345

ISBN-13: 0801861306

DOWNLOAD EBOOK →

"Highly recommended for a wide variety of audiences in addition to physicians and medical students... Fortunately, some of Childs's concepts are being applied to medical teaching already, but I know of no better synthesis in one book." -- Perspectives in Biology and Medicine

Simulation and Modeling Methodologies, Technologies and Applications

Simulation and Modeling Methodologies, Technologies and Applications PDF

Author: Mohammad S. Obaidat

Publisher: Springer

Published: 2017-10-26

Total Pages: 316

ISBN-13: 331969832X

DOWNLOAD EBOOK →

This Proceedings book reports on new and innovative solutions regarding methodologies and applications of modeling and simulation. It includes a set of selected, extended papers from the 6th International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2016), held in Lisbon, Portugal, from 29 to 31 July, 2016. The conference brought together researchers, engineers and practitioners interested in methodologies and applications of modeling and simulation. SIMULTECH 2016 received 76 submissions from 35 countries and all continents. After a double-blind paper review performed by the Program Committee, 18% were accepted as full papers and thus selected for oral presentations. Additional papers were accepted as short papers and posters. A further selection was made after the Conference, based also on the assessment of presentation quality and audience interest, so that this book includes the extended and revised versions of the very best papers from SIMULTECH 2016.

Perspectives on Genetic Discrimination

Perspectives on Genetic Discrimination PDF

Author: Thomas Lemke

Publisher: Routledge

Published: 2013-07-18

Total Pages: 172

ISBN-13: 1134056915

DOWNLOAD EBOOK →

Over the past 15 years, a series of empirical studies in different countries have shown that our increasing genetic knowledge leads to new forms of exclusion, disadvantaging and stigmatization. The spectrum of this "genetic discrimination" ranges from disadvantages at work, via problems with insurance policies, to difficulties with adoption agencies. The empirical studies on the problem of genetic discrimination have not gone unnoticed. Since the beginning of the 1990s, a series of legislative initiatives and statements, both on the national level and on the part of international and supranational organizations and commissions, have been put forward as ways of protecting people from genetic discrimination. This is the first book to critically evaluate the empirical evidence and the theoretical usefulness of the concept of "genetic discrimination." It discusses the advantages and limitations of adopting the concept, and offers a more complex account distinguishing between several dimensions and forms of genetic discrimination.

Liver Disease in Children

Liver Disease in Children PDF

Author: Frederick J. Suchy

Publisher: Cambridge University Press

Published: 2007-05-07

Total Pages: 995

ISBN-13: 1139464035

DOWNLOAD EBOOK →

Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Logic Synthesis and Verification

Logic Synthesis and Verification PDF

Author: Soha Hassoun

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 458

ISBN-13: 1461508177

DOWNLOAD EBOOK →

Research and development of logic synthesis and verification have matured considerably over the past two decades. Many commercial products are available, and they have been critical in harnessing advances in fabrication technology to produce today's plethora of electronic components. While this maturity is assuring, the advances in fabrication continue to seemingly present unwieldy challenges. Logic Synthesis and Verification provides a state-of-the-art view of logic synthesis and verification. It consists of fifteen chapters, each focusing on a distinct aspect. Each chapter presents key developments, outlines future challenges, and lists essential references. Two unique features of this book are technical strength and comprehensiveness. The book chapters are written by twenty-eight recognized leaders in the field and reviewed by equally qualified experts. The topics collectively span the field. Logic Synthesis and Verification fills a current gap in the existing CAD literature. Each chapter contains essential information to study a topic at a great depth, and to understand further developments in the field. The book is intended for seniors, graduate students, researchers, and developers of related Computer-Aided Design (CAD) tools. From the foreword: "The commercial success of logic synthesis and verification is due in large part to the ideas of many of the authors of this book. Their innovative work contributed to design automation tools that permanently changed the course of electronic design." by Aart J. de Geus, Chairman and CEO, Synopsys, Inc.

Genetic Design Automation

Genetic Design Automation PDF

Author: Hasan Baig

Publisher: Springer Nature

Published: 2020-09-25

Total Pages: 171

ISBN-13: 3030523551

DOWNLOAD EBOOK →

This textbook introduces readers to the recent advances in the emerging field of genetic design automation (GDA). Starting with an introduction and the basic concepts of molecular biology, the authors provide an overview of various genetic design automation tools. The authors then present the DVASim tool (Dynamic Virtual Analyzer and Simulator) which is used for the analysis and verification of genetic logic circuits. This includes methods and algorithms for the timing and threshold value analyses of genetic logic circuits. Next, the book presents the GeneTech tool (A technology mapping tool for genetic circuits) and the methods developed for optimization, synthesis, and technology mapping of genetic circuits. Chapters are followed by exercises which give readers hands-on practice with the tools presented. The concepts and algorithms are thoroughly described, enabling readers to improve the tools or use them as a starting point to develop new tools. Both DVASim and GeneTech are available from the developer’s website, free of charge. This book is intended for a multidisciplinary audience of computer scientists, engineers and biologists. It provides enough background knowledge for computer scientists and engineers, who usually do not have any background in biology but are interested to get involved in this domain. This book not only presents an accessible basic introduction to molecular biology, it also includes software tools which allow users to perform laboratory experiments in a virtual in-silico environment. This helps newbies to get a quick start in understanding and developing genetic design automation tools. The third part of this book is particular useful for biologists who usually find it difficult to grasp programming and are reluctant to developing computer software. They are introduced to the graphical programming language, LabVIEW, from which they can start developing computer programs rapidly. Readers are further provided with small projects which will help them to start developing GDA tools.

The Anatomy of an English Paragraph

The Anatomy of an English Paragraph PDF

Author: Mahmoud Elsayess

Publisher: AuthorHouse

Published: 2023-06-25

Total Pages: 509

ISBN-13:

DOWNLOAD EBOOK →

The intent of my book is to assist writers of all ages and levels of expertise in improving their skills in discovering the attributes of successful paragraph construction with an in-depth understanding of the dynamics of writing award-winning essays. The most critical component of competitive success is the ability to translate an idea into a comprehensive written report. The MEALS (Main point, Evidence, Analysis, Logic, and synonym), an acronym, is a tool designed to act as a guide to promote ease and excellence in writing endeavors. During his graduate work, Dr. Elsayess developed a new tool with the acronym MEALS. The MEALS method could assist while creating written works to earn a degree. In addition, using this method could allow students to move ahead with a good competency level for writing. Dr. Elsayess utilized the MEALS tool for assessing his students and developing his book. Not only did Lovitts (2007) report a high rate of unacceptable dissertations would lead to university dropout, but also, Lovitts (2007) reported that the Council of Graduate Schools indicated that “a 50% student dropout rate, writing the dissertation reported as the major stumbling block.” Reference: Lovitts, B. E. (2007). Making the implicit explicit: Creating performance expectations for the dissertation. Stylus Publishing, LLC

Disorders of Hemoglobin

Disorders of Hemoglobin PDF

Author: Martin H. Steinberg

Publisher: Cambridge University Press

Published: 2001

Total Pages: 1254

ISBN-13: 9780521632669

DOWNLOAD EBOOK →

Disorders of Hemoglobin stands tall as the definitive work on the genetics, pathophysiology, and clinical management of hemoglobinopathies and thalassemia. Drs. Steinberg, Forget, Higgs, and Nagel have gathered the world authorities on the science and clinical management of these disorders and created the authoritative textbook for researchers and clinicians alike.Authors describe the scientific basis of clinical features and provide clinicians with a clear background of disorders they treat and scientists with an essential link between their research and its clinical manifestation. Disorders of Hemoglobin is the only single-source reference on hemoglobinopathies for hematologists, pediatricians, clinical investigators, and geneticists worldwide.