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Author: Mark Wheelis
Publisher: Jones & Bartlett Learning
Published: 2008
Total Pages: 525
ISBN-13: 076371075X
DOWNLOAD EBOOK →This text balances brevity and clarity in a condensed introduction to microbiology. It contains a manageable amount of detail and yet covers the full range and diversity of the microbial world.
Author: Wheelis
Publisher: Jones & Bartlett Learning
Published: 2007-12
Total Pages:
ISBN-13: 9780763756642
DOWNLOAD EBOOK →Author: Daniel D. Chiras
Publisher: Jones & Bartlett Publishers
Published: 2008-03-14
Total Pages:
ISBN-13: 9780763759384
DOWNLOAD EBOOK →Author: National Library of Medicine (U.S.)
Publisher:
Published: 1982
Total Pages: 64
ISBN-13:
DOWNLOAD EBOOK →Author: Vishal Jain
Publisher: Springer Nature
Published: 2020-03-09
Total Pages: 418
ISBN-13: 3030408507
DOWNLOAD EBOOK →This unique book introduces a variety of techniques designed to represent, enhance and empower multi-disciplinary and multi-institutional machine learning research in healthcare informatics. Providing a unique compendium of current and emerging machine learning paradigms for healthcare informatics, it reflects the diversity, complexity, and the depth and breadth of this multi-disciplinary area. Further, it describes techniques for applying machine learning within organizations and explains how to evaluate the efficacy, suitability, and efficiency of such applications. Featuring illustrative case studies, including how chronic disease is being redefined through patient-led data learning, the book offers a guided tour of machine learning algorithms, architecture design, and applications of learning in healthcare challenges.
Author: Ute Roessner
Publisher: Humana
Published: 2016-08-23
Total Pages: 0
ISBN-13: 9781493963010
DOWNLOAD EBOOK →Classical natural product chemistry is transitioning to modern day metabolomics as a result of the advent of comprehensive analytical platforms and sensitive analytical instrumentation. Therefore, it is worthwhile to summarize recent developments with current analytical platforms and highlight how metabolomics is being integrated into this classical field to dereplicate and profile natural product extracts. Metabolomics Tools for Natural Product Discoveries: Methods and Protocols aims to unite diverse and recently developed methodologies and protocols in order to identify bioactive secondary metabolites for the purpose of drug discovery. Some topics covered in this volume include applications for the extraction of selected natural products from less common sources such as bryophytes and hard corals, various biological assays, comprehensive applications and strategies for GC-MS, LC-MS, and NMR, as well as protocols and strategies for the structure elucidation of isolated natural products. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible Metabolomics Tools for Natural Product Discoveries: Methods and Protocols seeks to serve both professionals and research students with its well-honed methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses.
Author: Dev Bukhsh Singh
Publisher: Springer Nature
Published: 2020-07-02
Total Pages: 458
ISBN-13: 9811555303
DOWNLOAD EBOOK →This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances. Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecular motors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.
Author: Robert M. Rydzewski
Publisher: Elsevier
Published: 2010-07-07
Total Pages: 600
ISBN-13: 9780080914886
DOWNLOAD EBOOK →Drug discovery increasingly requires a common understanding by researchers of the many and diverse factors that go into the making of new medicines. The scientist entering the field will immediately face important issues for which his education may not have prepared him: project teams, patent law, consultants, target product profiles, industry trends, Gantt charts, target validation, pharmacokinetics, proteomics, phenotype assays, biomarkers, and many other unfamiliar topics for which a basic understanding must somehow be obtained. Even the more experienced scientist can find it frustratingly difficult to get an overview of the many factors involved in modern drug discovery and often only after years of exploring does a whole and integrated picture emerge in the mind of the researcher. Real World Drug Discovery: A Chemist’s Guide to Biotech and Pharmaceutical Research presents this kind of map of the landscape of drug discovery. In a single, readable volume it outlines processes and explains essential concepts and terms for the recent science graduate wondering what to expect in pharma or biotech, the medicinal chemist seeking a broader and more timely understanding of the industry, or the contractor or collaborator whose understanding of the commercial drug discovery process could increase the value of his contribution to it. Interviews with well-known experts in many of the fields involved, giving insightful comments from authorities on many of the sub-disciplines important to cutting edge drug discovery. Helpful suggestions gleaned from years of experience in biotech and pharma, which represents a repository drug discovery "lore" not previously available in any book. "Periodic Table of Drugs" listing current top-selling drugs arranged by target and laid out so that structural similarities and differences are plain and clear. Extensive use of diagrams to illustrate concepts like biotech startup models, preteomic profiling for target identification, Gantt charts for project planning, etc.
Author: C.Yan Cheng
Publisher: Springer
Published: 2022-08-30
Total Pages: 0
ISBN-13: 9783030777814
DOWNLOAD EBOOK →This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.
Author: Manoj Kumar Jhariya
Publisher: Springer Nature
Published: 2021-10-21
Total Pages: 873
ISBN-13: 9811632073
DOWNLOAD EBOOK →This edited book provides a comprehensive account of the sustainable intensification process through various forms of case studies and scientific approaches studied across the globe. It also focuses on the agroecosystem services and their subsequent management for ecological integrity. The book helps to understand the interconnection of food, nutrition, economic growth, and environmental security on the planet. It provides comprehensive information with photographic illustration and various other forms of scientific databases on sustainable intensification of agroecosystems. The book also supports decision-making, strategies, and policy formulation for effective implementation of sustainable intensification towards higher productivity along with maintenance and management of agroecosystem services. Proper sustainable intensification of agroecosystem services and their management by maintaining ecological harmony is the future prospect for sustainable development. High input agriculture gives rise to a high-energy footprint, agricultural pollution, resource depletion, loss of agro-biodiversity, and decline of human health. Through this connection, the sustainable intensification approach addresses the advanced food security, sustainability, and overall prosperity of humankind. The book is helpful for both undergraduate and postgraduate students, policymakers, the farming community, as well as the scientific community across the globe to understand the concept of sustainable intensification and its application in relevant fields for proper management of agroecosystems services.
