Ion Beam Therapy

Ion Beam Therapy PDF

Author: Ute Linz

Publisher: Springer Science & Business Media

Published: 2011-12-09

Total Pages: 728

ISBN-13: 3642214142

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The book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated by the leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-side collection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and accelerator physics, radiobiology, computer science, engineering, and health economics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter the field of ion beam therapy as a researcher. However, it is also written for the interested public and for patients who might want to learn about this treatment option.

Carbon-Ion Radiotherapy

Carbon-Ion Radiotherapy PDF

Author: Hirohiko Tsujii

Publisher: Springer Science & Business Media

Published: 2013-12-25

Total Pages: 284

ISBN-13: 4431544577

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This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.

Proton and Carbon Ion Therapy

Proton and Carbon Ion Therapy PDF

Author: C-M Charlie Ma

Publisher: CRC Press

Published: 2012-10-09

Total Pages: 258

ISBN-13: 1439816077

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Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings.

Proton and Carbon Ion Therapy

Proton and Carbon Ion Therapy PDF

Author: C-M Charlie Ma

Publisher: CRC Press

Published: 2012-10-09

Total Pages: 254

ISBN-13: 1439816085

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Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and trea

Relative Biological Effectiveness in Ion Beam Therapy

Relative Biological Effectiveness in Ion Beam Therapy PDF

Author: International Atomic Energy Agency

Publisher:

Published: 2008

Total Pages: 0

ISBN-13: 9789201078070

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This publication covers all the aspects of the relative biological effectiveness (RBE) of ion beams, including laboratory measurements of RBE and the important variables that influence it, dose related quantities and units, and approaches to the clinical use of the concept of RBE based on experimental findings, theoretical models, and previous clinical experience with fast neutrons and ions. This publication is the result of a joint initiative of the IAEA and ICRU (International Commission on Radiation Units and Measurements). It is the only current extensive review of ion beam RBE, and it is expected to be a reference volume for existing and future centres employing ion beams for therapeutic use.

Protontherapy Versus Carbon Ion Therapy

Protontherapy Versus Carbon Ion Therapy PDF

Author: Marcos d’Ávila Nunes

Publisher: Springer

Published: 2016-10-22

Total Pages: 110

ISBN-13: 9783319367187

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This book presents a comparison analysis of two cancer treatment therapies: carbon ion therapy and protontherapy. It is divided in 5 sections. The first ones gives the reader a brief history of Radiotherapy and types of radiation. In the second section, the techniques and equipments, including new ones in development such as Cyclinac , Laser and DWA, are described. The third section describes biophysical (such as stopping power and LET) and biological (such as RBE and OER) properties, the fundamental experiments and clinical area. The fourth section presents models and the fifth section compares both techniques, showing advantages and disadvantages of each, and their similarities.

Nanoscale Insights into Ion-Beam Cancer Therapy

Nanoscale Insights into Ion-Beam Cancer Therapy PDF

Author: Andrey V. Solov’yov

Publisher: Springer

Published: 2016-12-07

Total Pages: 508

ISBN-13: 3319430300

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This book provides a unique and comprehensive overview of state-of-the-art understanding of the molecular and nano-scale processes that play significant roles in ion-beam cancer therapy. It covers experimental design and methodology, and reviews the theoretical understanding of the processes involved. It offers the reader an opportunity to learn from a coherent approach about the physics, chemistry and biology relevant to ion-beam cancer therapy, a growing field of important medical application worldwide. The book describes phenomena occurring on different time and energy scales relevant to the radiation damage of biological targets and ion-beam cancer therapy from the molecular (nano) scale up to the macroscopic level. It illustrates how ion-beam therapy offers the possibility of excellent dose localization for treatment of malignant tumours, minimizing radiation damage in normal tissue whilst maximizing cell-killing within the tumour, offering a significant development in cancer therapy. The full potential of such therapy can only be realized by better understanding the physical, chemical and biological mechanisms, on a range of time and space scales that lead to cell death under ion irradiation. This book describes how, using a multiscale approach, experimental and theoretical expertise available can lead to greater insight at the nanoscopic and molecular level into radiation damage of biological targets induced by ion impact. The book is intended for advanced students and specialists in the areas of physics, chemistry, biology and medicine related to ion-beam therapy, radiation protection, biophysics, radiation nanophysics and chemistry, atomic and molecular physics, condensed matter physics, and the physics of interaction of charged particles with matter. One of the most important features of the book is the inclusive multiscale approach to the understanding of complex and highly interdisciplinary processes behind ion-beam cancer therapy, which stretches from the atomistic level up to the biological scale and is demonstrated to be in excellent agreement with experimental observations.

Practical Implementation of Light in Ion Beam Treatments

Practical Implementation of Light in Ion Beam Treatments PDF

Author: Michael Farley Moyers

Publisher:

Published: 2013-03-01

Total Pages: 580

ISBN-13: 9781930524552

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This book is indexed and includes a DVD with color images and tables. The number of light ion beam (including proton beam) treatment programs is rapidly increasing worldwide; however, there are currently no practical guides to support the acceptance testing, commissioning, planning, and continuing quality assurance of these programs. This book is aimed at those individuals who participate in the delivery and planning aspects of light ion beam treatments. Typically these individuals are medical physicists with responsibilities for calibration and verification of beam delivery, quality assurance, and computerized treatment planning; however other individuals may also find the book useful. This book provides practical recommendations and guides the reader through the steps of the treatment process, focusing on practical details.

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