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Investigations of Cellular and Molecular Biophysical Properties by Atomic Force Microscopy Nanorobotics

Author: Mi Li

Publisher: Springer

Published: 2017-10-06

Total Pages: 135

ISBN-13: 9811068291

This book presents methodological and application research in detecting cellular and molecular biophysical properties based on atomic force microscopy (AFM) nanorobotics. Series methods for in situ label-free visualizing and quantifying the multiple physical properties of single cells and single molecules were developed, including immobilization strategies for observing fine structures of living cells, measurements of single-cell mechanics, force recognition of molecular interactions, and mapping protein organizations on cell surface. The biomedical applications of these methods in clinical lymphoma treatments were explored in detail, including primary sample preparation, cancer cell recognition, AFM detection and data analysis. Future directions about the biomedical applications of AFM are also given.

Atomic Force Microscopy for Nanoscale Biophysics

Author: Mi Li

Publisher: Elsevier

Published: 2023-02-15

Total Pages: 338

ISBN-13: 0323958338

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Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution. Summarizes the recent progress of atomic force microscopy in biomedical applications Presents the methods and skills of applying atomic force microscopy Aids researchers in investigating the nanoscale biophysics of diverse biological systems

Microscopic Techniques for the Non-Expert

Author: Sathish-Kumar Kamaraj

Publisher: Springer Nature

Published: 2022-06-27

Total Pages: 251

ISBN-13: 3030995429

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This book covers fundamental microscopic techniques for Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), and other microscopic tools. It provides step-by-step instructions and explanations of the basic fundamental concepts and mechanisms and guides the reader on resolving queries related to taking and analyzing microscopy images. The latest advancements and developments in microscopic equipment are described. Theoretical background on microscopy is also provided to enhance the reader’s understanding of microscopy techniques and tools. Microscopic Techniques for the Non-Expert is an ideal book for undergraduate and postgraduate students, as well as researchers with a background in environmental science, materials science, biomedicine, engineering, or bio-nanotechnology.

Selected Topics in Micro/Nano-robotics for Biomedical Applications

Author: Yi Guo

Publisher: Springer Science & Business Media

Published: 2012-09-25

Total Pages: 201

ISBN-13: 1441984119

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Micro/Nano-robotics for Biomedical Applications features a system approach and incorporates modern methodologies in autonomous mobile robots for programmable and controllable micro/nano-robots aiming at biomedical applications. The book provides chapters of instructional materials in micro/nanorobotics for biomedical applications. The book features lecture units on micro/nanorobot components and techniques, including sensors, actuator, power supply, and micro/nano-fabrication and assembly. It also contains case studies on using micro/nano-robots in biomedical environments and in biomedicine, as well as a design example to conceptually develop a Vitamin-pill sized robot to enter human’s gastrointestinal tract. Laboratory modules to teach robot navigation and cooperation methods suitable to biomedical applications will be also provided based on existing simulation and robot platforms.

Molecular Manipulation with Atomic Force Microscopy

Author: Anne-Sophie Duwez

Publisher: CRC Press

Published: 2011-12-07

Total Pages: 285

ISBN-13: 1439809674

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With the invention of scanning probe techniques in the early 1980s, scientists can now play with single atoms, single molecules, and even single bonds. Force, dynamics, and function can now be probed at the single-molecule level. Molecular Manipulation with Atomic Force Microscopy (AFM) presents a series of topics that discuss concepts and methodol

Nanotechnology in the Food, Beverage and Nutraceutical Industries

Author: Qingrong Huang

Publisher: Elsevier

Published: 2012-04-19

Total Pages: 475

ISBN-13: 085709565X

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Nanotechnology has the potential to impact on food processing significantly. This important book summarises current research in this area and provides an overview of both current and possible future applications of nanotechnologies in the food industry. Issues such as safety and regulation are also addressed. After an introductory overview, the first part discusses general issues such as risk assessment, the regulatory framework, detection and characterisation of nanoparticles in food. Part two summarises the wide range of applications of nanotechnology in food processing, including nanoscale nutraceutical delivery systems, nanoemulsions and colloids, nanoscale rapid detection devices for contaminants, nanofiltration and nanocomposite packaging materials. With its distinguished editor and international team of contributors, Nanotechnology in the food, beverage and nutraceutical industries is a valuable reference work for both food processors and those researching this expanding field. Discusses issues such as risk assessment, regulatory framework, detection and characterisation of nanoparticles in food Summarises the wide range of applications of nanotechnology in food processing, including nutraceutical delivery and packaging materials Written by a distinguished team of international contributors, this book is an invaluable reference for industry professionals and academics alike

21st Century Nanoscience

Author: Klaus D. Sattler

Publisher: CRC Press

Published: 2022-01-18

Total Pages: 4153

ISBN-13: 1351260553

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This 21st Century Nanoscience Handbook will be the most comprehensive, up-to-date large reference work for the field of nanoscience. Handbook of Nanophysics, by the same editor, published in the fall of 2010, was embraced as the first comprehensive reference to consider both fundamental and applied aspects of nanophysics. This follow-up project has been conceived as a necessary expansion and full update that considers the significant advances made in the field since 2010. It goes well beyond the physics as warranted by recent developments in the field. Key Features: Provides the most comprehensive, up-to-date large reference work for the field. Chapters written by international experts in the field. Emphasises presentation and real results and applications. This handbook distinguishes itself from other works by its breadth of coverage, readability and timely topics. The intended readership is very broad, from students and instructors to engineers, physicists, chemists, biologists, biomedical researchers, industry professionals, governmental scientists, and others whose work is impacted by nanotechnology. It will be an indispensable resource in academic, government, and industry libraries worldwide. The fields impacted by nanoscience extend from materials science and engineering to biotechnology, biomedical engineering, medicine, electrical engineering, pharmaceutical science, computer technology, aerospace engineering, mechanical engineering, food science, and beyond.

Nanoscale Biophysics of the Cell

Author: Mohammad Ashrafuzzaman

Publisher: Springer

Published: 2018-04-12

Total Pages: 386

ISBN-13: 3319774654

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Macroscopic cellular structures and functions are generally investigated using biological and biochemical approaches. But these methods are no longer adequate when one needs to penetrate deep into the small-scale structures and understand their functions. The cell is found to hold various physical structures, molecular machines, and processes that require physical and mathematical approaches to understand and indeed manipulate them. Disorders in general cellular compartments, perturbations in single molecular structures, drug distribution therein, and target specific drug-binding, etc. are mostly physical phenomena. This book will show how biophysics has revolutionized our way of addressing the science and technology of nanoscale structures of cells, and also describes the potential for manipulating the events that occur in them.

Life at the Nanoscale

Author: Yves Dufrene

Publisher: CRC Press

Published: 2019-03-28

Total Pages: 460

ISBN-13: 981426797X

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Proceeding from basic fundamentals to applications, this volume provides a comprehensive overview of the use of AFM and related scanning probe microscopies for cell surface analysis. It covers all cell types, from viruses and protoplasts to bacteria and animal cells. It also discusses a range of advanced AFM modalities, including high-resolution imaging, nanoindentation measurements, recognition imaging, and single-molecule and single-cell force spectroscopy. The book covers methodologies for preparing and analyzing cells and membranes of all kinds and highlights recent examples to illustrate the power of AFM techniques in life sciences and nanomedicine.

Forensic Microscopy

Author: Ritesh K Shukla

Publisher: CRC Press

Published: 2022-07-12

Total Pages: 367

ISBN-13: 1000600149

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Forensic Microscopy: Truth Under the Lenses provides an overview and understanding of the various types of microscopes and their techniques employed in forensic science. The book emphasizes both the theoretical and practical aspects of microscopy to enrich the reader’s understanding of the various tools, techniques, and utility—including strengths and weaknesses—of types of microscopes in analyzing certain forms of evidence. The book begins with the history of microscopes, the basic optics for microscopy, then moves to advanced microscopies such as electron microscopes and atomic force microscopes. In addition to the various types of microscopes and how to use and best utilize them, the book looks at the analysis of specific types of evidence, including hair, fiber, fingerprint, body fluids, tool marks, ink, pollen grains, spores, diatoms, bullets, cartridges, among other evidence types. Since forensic science is an applied, hands-on discipline, the book includes both a theoretical and a practical approach to the topic. Key Features: Addresses simple to advanced microscopy techniques for the effective analyses of trace evidence Pairs chapters on a particular type of microscopy, explaining it thoroughly, before delving into specific usage for forensic applications Presents theories and as well as real-world application of concepts Provides abundant micro-photographs, including graphical representations and flow charts, to illustrate concepts clearly Forensic Microscopy serves as a helpful reference for undergraduate and postgraduate students in forensic science, forensic biology, forensic chemistry and related programs. It is also recommended for research students, academicians, technicians, industry and laboratory professionals working on trace evidence analysis.