Introduction to Molecular Biophysics

Introduction to Molecular Biophysics PDF

Author: Jack A. Tuszynski

Publisher: CRC Press

Published: 2003-02-26

Total Pages: 579

ISBN-13: 0203009967

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Molecular biophysics is a rapidly growing field of research that plays an important role in elucidating the mysteries of life's molecules and their assemblies, as well as the relationship between their structure and function. Introduction to Molecular Biophysics fills an existing gap in the literature on this subject by providing the reader with th

Methods in Molecular Biophysics

Methods in Molecular Biophysics PDF

Author: Nathan R. Zaccai

Publisher: Cambridge University Press

Published: 2017-05-18

Total Pages: 710

ISBN-13: 1108508804

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Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.

Molecular Biophysics

Molecular Biophysics PDF

Author: Michel Daune

Publisher: Oxford University Press, USA

Published: 1999

Total Pages: 499

ISBN-13: 9780198577836

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This new textbook offers a comprehensive introduction to the molecular physics of biological systems: it seeks to explain how the laws and concepts of physics apply to the living world at the molecular and subcellular level, with an emphasis on electrical and dynamical behaviour. The book is organized into five parts: * conformation of biopolymers * dynamics of biopolymers * hydration of biopolymers * biopolymers as polyelectrolytes *association between molecules The author adopts a multi-disciplinary approach and limits mathematics only to what is strictly necessary for the development of the subject. The text should be suitable for students from a wide range of backgrounds in biology, physics or chemistry taking advanced courses in molecular biophysics or biophysical chemistry.

The Physics of Proteins

The Physics of Proteins PDF

Author: Hans Frauenfelder

Publisher: Springer Science & Business Media

Published: 2010-05-30

Total Pages: 423

ISBN-13: 1441910441

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Provides an introduction to the structure and function of biomolecules --- especially proteins --- and the physical tools used to investigate them The discussion concentrates on physical tools and properties, emphasizing techniques that are contributing to new developments and avoiding those that are already well established and whose results have already been exploited fully New tools appear regularly - synchrotron radiation, proton radiology, holography, optical tweezers, and muon radiography, for example, have all been used to open new areas of understanding

Computer Simulation and Data Analysis in Molecular Biology and Biophysics

Computer Simulation and Data Analysis in Molecular Biology and Biophysics PDF

Author: Victor Bloomfield

Publisher: Springer Science & Business Media

Published: 2009-06-05

Total Pages: 325

ISBN-13: 1441900837

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This book provides an introduction to two important aspects of modern bioch- istry, molecular biology, and biophysics: computer simulation and data analysis. My aim is to introduce the tools that will enable students to learn and use some f- damental methods to construct quantitative models of biological mechanisms, both deterministicandwithsomeelementsofrandomness;tolearnhowconceptsofpr- ability can help to understand important features of DNA sequences; and to apply a useful set of statistical methods to analysis of experimental data. The availability of very capable but inexpensive personal computers and software makes it possible to do such work at a much higher level, but in a much easier way, than ever before. TheExecutiveSummaryofthein?uential2003reportfromtheNationalAcademy of Sciences, “BIO 2010: Transforming Undergraduate Education for Future - search Biologists” [12], begins The interplay of the recombinant DNA, instrumentation, and digital revolutions has p- foundly transformed biological research. The con?uence of these three innovations has led to important discoveries, such as the mapping of the human genome. How biologists design, perform, and analyze experiments is changing swiftly. Biological concepts and models are becoming more quantitative, and biological research has become critically dependent on concepts and methods drawn from other scienti?c disciplines. The connections between the biological sciences and the physical sciences, mathematics, and computer science are rapidly becoming deeper and more extensive.

Biophysics

Biophysics PDF

Author: Rodney Cotterill

Publisher: John Wiley & Sons

Published: 2003-07-07

Total Pages: 408

ISBN-13: 0470854561

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Biophysics is an evolving, multidisciplinary subject which applies physics to biological systems and promotes an understanding of their physical properties and behaviour. Biophysics: An Introduction, is a concise balanced introduction to this subject. Written in an accessible and readable style, the book takes a fresh, modern approach with the author successfully combining key concepts and theory with relevant applications and examples drawn from the field as a whole. Beginning with a brief introduction to the origins of biophysics, the book takes the reader through successive levels of complexity, from atoms to molecules, structures, systems and ultimately to the behaviour of organisms. The book also includes extensive coverage of biopolymers, biomembranes, biological energy, and nervous systems. The text not only explores basic ideas, but also discusses recent developments, such as protein folding, DNA/RNA conformations, molecular motors, optical tweezers and the biological origins of consciousness and intelligence. Biophysics: An Introduction * Is a carefully structured introduction to biological and medical physics * Provides exercises at the end of each chapter to encourage student understanding Assuming little biological or medical knowledge, this book is invaluable to undergraduate students in physics, biophysics and medical physics. The book is also useful for graduate students and researchers looking for a broad introduction to the subject.

Biophysics

Biophysics PDF

Author: Roland Glaser

Publisher: Springer Science & Business Media

Published: 2004-10-22

Total Pages: 388

ISBN-13: 9783540670889

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Biophysics is the science of physical principles underlying the "phenomenon of life" on all levels of organization. This book begins by explaining molecular and ionic interactions, movements, excitation and energy transfer, and the self-organization of supramolecular structures. Then the biological organism is introduced as a non-equilibrium system. Finally, system analyses are discussed as well as environmental biophysics, ecological interactions, growth, differentiation, and evolution. A growing number of applications in biotechnology are based on these biophysical concepts.

Introduction to Experimental Biophysics

Introduction to Experimental Biophysics PDF

Author: Jay L. Nadeau

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 658

ISBN-13: 1439897409

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Increasing numbers of physicists, chemists, and mathematicians are moving into biology, reading literature across disciplines, and mastering novel biochemical concepts. To succeed in this transition, researchers must understand on a practical level what is experimentally feasible. The number of experimental techniques in biology is vast and often s

The Physical Basis of Biochemistry

The Physical Basis of Biochemistry PDF

Author: Peter R. Bergethon

Publisher: Springer Science & Business Media

Published: 2010-09-10

Total Pages: 950

ISBN-13: 1441963243

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Biological chemistry has changed since the completion of the human genome project. There is a renewed interest and market for individuals trained in biophysical chemistry and molecular biophysics. The Physical Basis of Biochemistry, Second Edition, emphasizes the interdisciplinary nature of biophysical chemistry by incorporating the quantitative perspective of the physical sciences without sacrificing the complexity and diversity of the biological systems, applies physical and chemical principles to the understanding of the biology of cells and explores the explosive developments in the area of genomics, and in turn, proteomics, bioinformatics, and computational and visualization technologies that have occurred in the past seven years. The book features problem sets and examples, clear illustrations, and extensive appendixes that provide additional information on related topics in mathematics, physics and chemistry.

Introductory Biophysics

Introductory Biophysics PDF

Author: James R. Claycomb

Publisher: Jones & Bartlett Learning

Published: 2011

Total Pages: 375

ISBN-13: 0763779989

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Designed for biology, physics, and medical students, Introductory Biophysics: Perspectives on the Living State, provides a comprehensive overview of the complex subject of biological physics. The companion CD-ROM, with MATLAB examples and the student version of QuickFieldTM, allows the student to perform biophysical simulations and modify the textbook example files. Included in the text are computer simulations of thermodynamics, astrobiology, the response of living cells to external fields, chaos in population dynamics, numerical models of evolution, electrical circuit models of cell suspension, gap junctions, and neuronal action potentials. With this text students will be able to perform biophysical simulations within hours. MATLAB examples include; the Hodgkin Huxley equations; the FitzHugh-Nagumo model of action potentials; fractal structures in biology; chaos in population dynamics; the cellular automaton model (the game of life); pattern formation in reaction-diffusion systems. QuickFieldTM tutorials and examples include; calculation of currents in biological tissue; cells under electrical stimulation; induced membrane potentials; heat transfer and analysis of stress in biomaterials.