Diagnosis and Management of Cholangiocarcinoma

Diagnosis and Management of Cholangiocarcinoma PDF

Author: James H. Tabibian

Publisher: Springer Nature

Published: 2021-05-28

Total Pages: 589

ISBN-13: 3030709361

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This book provides a comprehensive, state-of-the-art overview of cholangiocarcinoma (CCA). The text is structured to effectively present a broad yet concise overview of bile duct cancer, its relevant definitions, classification schemata, clinical management tenets, translational (including molecular and cellular) facets, and future directions. The book features numerous high-yield illustrations and is authored by an eclectic range of renowned experts in various areas of CCA, reflecting the multidisciplinary nature of the field. Filling a critical gap in the field, Diagnosis and Management of Cholangiocarcinoma: A Multidisciplinary Approach is a valuable resource for clinicians and practitioners who treat patients with bile duct cancer.

Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma

Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma PDF

Author: Alfredo Guglielmi

Publisher: Springer Science & Business Media

Published: 2007-11-21

Total Pages: 241

ISBN-13: 8847007291

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This book contains an up-to-date review of diagnostic and staging tools of cholangiocarcinoma, a guide to optimal selection of therapeutic modalities and a review of long-term outcome of surgery and liver transplantation. It also provides surgical techniques and principles for curative and palliative surgery. This book will appeal to physicians and hepatobiliary surgeons who want to improve their knowledge about surgical management of intrahepatic and hilar cholangiocarcinomas.

Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma PDF

Author: Timothy M. Pawlik

Publisher: Springer

Published: 2019-07-30

Total Pages: 215

ISBN-13: 3030222586

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This book provides a comprehensive review of the epidemiology, molecular pathogenesis, diagnosis and treatment of intrahepatic cholangiocarcinoma (ICC). It brings together an impressive group of international experts in cholangiocarcinoma research and clinical care. The book was organized and written to aid the clinician’s understanding of emerging research in cholangiocarcinoma and its application to the clinical care of patients with ICC. Each chapter details the scientific evidence to support clinical decisions that are needed to care for these complex patients. Focused chapters detail the epidemiology, diagnostic evaluation, as well as staging and prognosis of this disease. In addition to dedicated chapters on surgical management of ICC, a broad emphasis on locoregional therapies, including percutaneous ablation and transarterial therapies, is included. An up-to-date overview of the molecular pathogenesis and pathological assessment of ICC is detailed prior to chapters focusing on systemic chemotherapy and emerging novel therapy options. Intrahepatic Cholangiocarcinoma is not only an invaluable resource for many as they seek to provide the best multidisciplinary cancer care to patients with ICC, but also an opportunity to identify new avenues of scientific discovery that lead to significant advances in the diagnosis and management of ICC.

Hepatobiliary Cancer

Hepatobiliary Cancer PDF

Author: Paul H. Sugarbaker

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 455

ISBN-13: 1461526043

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When one deals with cancer, the hepatobiliary malignancies present a chal lenge to the oncologists that can be characterized as a series of unsolved clinical and biological dilemmas. Liver metastases from colorectal and other gastrointestinal malignancies, hepatocellular carcinoma, cholangiocar cinoma, and gall bladder cancer present an array of problems but have two features in common. These are high morbidity and mortality with an overall poor result from treatment. Why is it that hepatobiliary cancer carries with it such a dismal prognosis? First of all, these diseases present, for the most part, in an advanced state. To this point in time the oncologist has had no help from early diagnosis or screening. Only the occasional patient followed by ultrasound or a tumor marker has the disease diagnosed in an asymptomatic state. By the time these diseases become symptomatic, curative treatment options have usually disappeared. Evolution has placed the liver in a protected position in order to avoid injury to the soft parenchyma. As with many other internal organs, the nerve supply is extremely limited. These two anatomic features result in a great lack of early warning signs of cancer.

Perspective of tumor heterogeneity for treatments of intrahepatic cholangiocarcinoma with intrahepatic lithiasis

Perspective of tumor heterogeneity for treatments of intrahepatic cholangiocarcinoma with intrahepatic lithiasis PDF

Author: Wenjie Hou

Publisher: OAE Publishing Inc.

Published: 2023-07-31

Total Pages: 5

ISBN-13:

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The heterogeneity of tumors results in significantly distinct biological characteristics of intrahepatic cholangiocarcinoma (ICC) caused by different etiologies. Among them, ICC caused by intrahepatic lithiasis (IHL-ICC) presents challenges in early detection, tumor staging, and surgical treatment, and has the poorest prognosis among all etiologies of ICC patients. Thus, it is essential to focus on early assessment of the possibility of developing ICC, prompt intervention of intrahepatic lithiasis, anatomical resection of hepatic parenchyma corresponding to the branch of the intrahepatic bile duct undergoing cancerous transformation, and enhanced postoperative follow-up of hepatolithiasis and ICC for IHL-ICC patients. These interventions are crucial to improve the clinical outcomes and overall survival of IHL-ICC patients.

Surgical Oncology Manual

Surgical Oncology Manual PDF

Author: Frances C. Wright

Publisher: Springer Nature

Published: 2020-08-27

Total Pages: 526

ISBN-13: 3030483630

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This third edition manual provides a comprehensive, insightful, evidenced-based review of general surgical oncology and serves as a valuable resource for general surgeons in training, practicing general surgeons, and surgical oncologists. The volume describes a multidisciplinary approach that integrates clinical, radiologic, and pathologic data in formulating practical clinical management, and offers a practical approach to the most common situations when treating cancer patients. Each chapter focuses on an individual malignancy and describes the presentation of the malignancy, integrated management based on stage, landmark trials, and suggestions for who to discuss at multidisciplinary cancer conferences. Multiple tables in each chapter provide a concise yet comprehensive summary of the current status of the field. Clinical “pearls” or tips and tricks from high volume surgeons at the University of Toronto are also discussed. The third edition of the Surgical Oncology Manual will serve as a critical resource for general surgeons in training and practicing surgeons dealing with this challenging field.

The South Texas Health Status Review

The South Texas Health Status Review PDF

Author: Amelie G. Ramirez

Publisher: Springer

Published: 2013-06-29

Total Pages: 138

ISBN-13: 3319002333

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This book is a roadmap of the exact health disparities that burden the health of South Texas residents, especially Hispanics, compared to the rest of Texas and nation. This type of knowledge has the potential to fuel and motivate researchers and public health leaders to create and shape interventions to reverse those health disparities. Most notably, focus on obesity and diabetes prevention efforts and modifiable risk factors—such as nutrition, reproductive factors and access to health care—has significant potential to reduce the burden of disease in South Texas communities.South Texas, a 38-county region that spans 45,000 square miles along the Texas-Mexico border northward to the area around metropolitan Bexar County (home to San Antonio), is home to 18% of the state’s population. Yet South Texas residents, who are 68% Hispanic, struggle with lower educational levels, less income and less access to health care—and, as a result, suffer from a wide variety of health disparities. To study the health status and identify the exact health disparities that exist in the region, researchers from The UT Health Science Center at San Antonio teamed with researchers from the Texas Department of State Health Services to develop the South Texas Health Status Review.The Review team analyzed a variety of the latest county, state and national data to compare South Texas’ incidence, prevalence and mortality rates for more than 35 health indicators—from cancers to chronic diseases like diabetes to communicable diseases like HIV/AIDS to maternal health and even environmental health—to the rest of Texas and the nation by age, sex, race/ethnicity and rural/urban location.​

Cholangiocarcinoma

Cholangiocarcinoma PDF

Author: Dario Ribero

Publisher: Nova Science Publishers

Published: 2015

Total Pages: 0

ISBN-13: 9781634834889

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Cholangiocarcinoma is a heterogeneous group of neoplasms, which has a rising worldwide incidence. Therefore, it is now a major cause of cancer mortality. Diagnosis, staging, treatment approaches and outcomes differ significantly based on the location of the tumor. Given the challenges of remaining up-to-date in a rapidly expanding field, the aim of this monograph is to provide a comprehensive, fully referenced presentation of the state-of-the-art medical and surgical aspects relevant to the management of cholangiocarcinoma divided by the site of origin (i.e. intrahepatic, hilar and distal). The division of the book into these sections reflects the biological and clinical differences between these tumor types and will permit the authors to address the diagnostic, interventional or treatment issues specific to each tumor type. By presenting all medical and surgical aspects of cholangiocarcinoma in a systematic manner, this monograph will be a ready-to-use instrument for those interested in cholangiocarcinoma, including practicing physicians, residents, fellows and specialists. A list of 66 world-renowned experts contributed to the book, offering the readers the unique opportunity to have a broad perspective on these diseases, practical indications on patient selection and treatment that can be easily applied to both Eastern and Western clinical settings.

Hepatobiliary Surgery

Hepatobiliary Surgery PDF

Author: Ronald S. Chamberlain

Publisher: CRC Press

Published: 2003-01-01

Total Pages: 286

ISBN-13: 1498712940

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This book is written as a reference and guidebook for practicing surgeons, gastroenterologists, and interventional radiologists with an interest in hepatobiliary diseases. It presents a strategy to enhance surgeons practice and the care of patients.