Insights in autoimmune and autoinflammatory disorders: 2021
Author: Betty Diamond
Publisher: Frontiers Media SA
Published: 2023-03-14
Total Pages: 140
ISBN-13: 283250048X
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Emerging Insights in Controlling Autoimmunity
Author: Zahava Vadasz
Publisher: Frontiers Media SA
Published: 2022-09-19
Total Pages: 308
ISBN-13: 2889769984
DOWNLOAD EBOOK →Inborn Errors of Immunity
Author: Asghar Aghamohammadi
Publisher: Academic Press
Published: 2021-01-22
Total Pages: 396
ISBN-13: 0128231890
DOWNLOAD EBOOK →Awareness among clinicians about PIDs, which consist of more than 400 different entities, plays an important role in ensuring that patients receive a timely diagnosis. Furthermore, clinicians who are educated about PIDs can give their patients access to optimal management of their condition, thus helping the patient achieve a better quality-of-life and long-term prognosis. Inborn Errors of Immunity: A Practical Guide provides the most up-to-date information for busy students, nurses, clinical residents, practicing physicians, and even basic researchers. Readers will benefit from a well-structured breakdown of complicated PID diseases, including approaches to their clinical signs/symptoms and immunologic/laboratory findings. Presents valuable contribution of more than 40 expert chapter authors, from top centers spanning five continents, each in a specific PID field Covers various aspects of PID using updated clinical guidelines and standard stepwise pipelines Focuses on the latest developments in the molecular diagnosis and pathogenesis of diseases, with easy explanation and schematic representation of defective signaling pathways Includes dedicated sections for clinical features and immunological tests with carefully-curated figures of PID manifestations, imaging, and histological/pathological illustrations to create the first PID medial-color atlas Summarizes the updated conventional and specific treatments and follow-up notes for different PID diseases
Textbook of Autoinflammation
Author: Philip J. Hashkes
Publisher: Springer
Published: 2019-02-13
Total Pages: 820
ISBN-13: 3319986058
DOWNLOAD EBOOK →This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development. The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.
Childhood Uveitis
Author: C. Stephen Foster
Publisher:
Published: 2019-08-31
Total Pages:
ISBN-13: 9781733237611
DOWNLOAD EBOOK →The purpose of this book is to provide a concise but precise consensus on the impact of uveitis in children and on the diagnostic and therapeutic approaches. Experts in Ocular Immunology and Rheumatology were convened in an effort to provide guidelines in the diagnosis and treatment of uveitis in children. The result of those efforts are captured in this monograph.
Inflammasomes: Clinical and Therapeutic Implications
Author: Mario D. Cordero
Publisher: Springer
Published: 2018-09-04
Total Pages: 400
ISBN-13: 3319893904
DOWNLOAD EBOOK →The inflammasome is a protein complex composed of an intracellular sensor—typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1β and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1β has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic options. This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications. In this sense, we can find new drugs with inhibitory effects or old drugs with an inhibitory potential effect. There is a need for re-establishing the real benefits of the inflammasome inhibitions in pathological situations and the management of the differents diseases where inflammasomes are implicated.
The EBMT Handbook
Author: Nicolaus Kröger
Publisher:
Published: 2020-10-08
Total Pages: 688
ISBN-13: 9781013273674
DOWNLOAD EBOOK →This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Rheumatic Fever: 21st Century clinical and experimental insights
Author: Roney Orismar Sampaio
Publisher: Frontiers Media SA
Published: 2023-05-16
Total Pages: 194
ISBN-13: 2832523668
DOWNLOAD EBOOK →New Insights into Autoinflammatory Diseases: From Bench to Bedside
Author: Katerina Laskari
Publisher: Frontiers Media SA
Published: 2023-10-18
Total Pages: 137
ISBN-13: 2832536131
DOWNLOAD EBOOK →Systemic autoinflammatory diseases (SAIDs) are a growing group of rare disorders caused by dysregulation of the innate immune system leading to episodes of organ-specific and systemic inflammation. Autoinflammation as a distinct disease category was first reported in 1999 as a group of monogenic disorders with resultant activation of the inflammasome and cytokine excess, presenting as periodic fever and inflammation in serous membranes. Since this original description, the focus has shifted considerably to the inclusion of complex multifactorial conditions, and more than 30 associated genes have been identified. Disease severity varies from mild to life threatening. Advances in the understanding of the pathogenetic role of interleukin-1, have opened new promising horizons in the treatment of these patients, and significantly altered disease outcome.
Innate Immunity in Health and Disease
Author: Shailendra K. Saxena
Publisher: BoD – Books on Demand
Published: 2021-08-25
Total Pages: 416
ISBN-13: 1838807659
DOWNLOAD EBOOK →The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.
